(37 nodes) Regulation of tyrosine phosphorylation of STAT protein network (Xenopus tropicalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	socs3	Suppressor of cytokine signaling 3. (199 aa)
	socs1	Novel protein similar to suppressor of cytokine signaling 1. (211 aa)
	fgfr3	Fibroblast growth factor receptor. (829 aa)
	arl2bp	ADP-ribosylation factor-like protein 2-binding protein; Plays a role as an effector of the ADP-ribosylation factor- like protein 2, ARL2; Belongs to the ARL2BP family. (157 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	cav3.1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
	lyn	Tyrosine-protein kinase. (524 aa)
	cav3.2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
	IL6ST	Interleukin 6 signal transducer. (948 aa)
	LOC100496716	Uncharacterized protein. (195 aa)
	tnfrsf1a	Uncharacterized protein. (413 aa)
	hpx	MORC family CW-type zinc finger 2. (320 aa)
	crlf1	Mitochondrial E3 ubiquitin protein ligase 1. (387 aa)
	kit	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (966 aa)
	epo	Estrogen related receptor alpha. (183 aa)
	abca4-3	ATP binding cassette subfamily A member 4. (174 aa)
	nf2	FERM domain-containing protein. (635 aa)
	Cntf	Uncharacterized protein. (171 aa)
	Il6	Uncharacterized protein. (150 aa)
	LOC100485144	Poly [ADP-ribose] polymerase. (1540 aa)
	ENSXETP00000022548	IL12p40_C domain-containing protein. (249 aa)
	slc25a21-2	Poly [ADP-ribose] polymerase. (1541 aa)
	ENSXETP00000020553	Poly [ADP-ribose] polymerase. (412 aa)
	LOC101732564	Poly [ADP-ribose] polymerase. (1848 aa)
	LOC733765	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
	npas4-2	Neuronal PAS domain protein 4. (181 aa)
	LOC100485014	FERM domain-containing protein. (507 aa)
	sh2b3	Uncharacterized protein. (617 aa)
	cd40	CD40. (279 aa)
	parp9	Uncharacterized protein. (834 aa)
	socs3l	Suppressor of cytokine signaling 3. (211 aa)
	csf1r	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (935 aa)
	inpp5f	Spermatogenesis associated 13. (1077 aa)
	pibf1	Uncharacterized protein. (755 aa)
	clcf1	Cardiotrophin-like cytokine factor 1. (223 aa)
	parp14.2	Poly [ADP-ribose] polymerase. (1751 aa)
	ptpn2	Proteasome 26S subunit, non-ATPase 8. (498 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cntf	IL6ST	ENSXETP00000024819	ENSXETP00000038203	Uncharacterized protein.	Interleukin 6 signal transducer.	0.946
Cntf	Il6	ENSXETP00000024819	ENSXETP00000024453	Uncharacterized protein.	Uncharacterized protein.	0.578
Cntf	abca4-3	ENSXETP00000024819	ENSXETP00000028683	Uncharacterized protein.	ATP binding cassette subfamily A member 4.	0.604
Cntf	clcf1	ENSXETP00000024819	ENSXETP00000001596	Uncharacterized protein.	Cardiotrophin-like cytokine factor 1.	0.561
Cntf	npas4-2	ENSXETP00000024819	ENSXETP00000015873	Uncharacterized protein.	Neuronal PAS domain protein 4.	0.568
ENSXETP00000020553	parp9	ENSXETP00000020553	ENSXETP00000012055	Poly [ADP-ribose] polymerase.	Uncharacterized protein.	0.449
ENSXETP00000022548	Il6	ENSXETP00000022548	ENSXETP00000024453	IL12p40_C domain-containing protein.	Uncharacterized protein.	0.495
ENSXETP00000022548	LOC100496716	ENSXETP00000022548	ENSXETP00000036069	IL12p40_C domain-containing protein.	Uncharacterized protein.	0.471
IL6ST	Cntf	ENSXETP00000038203	ENSXETP00000024819	Interleukin 6 signal transducer.	Uncharacterized protein.	0.946
IL6ST	Il6	ENSXETP00000038203	ENSXETP00000024453	Interleukin 6 signal transducer.	Uncharacterized protein.	0.996
IL6ST	abca4-3	ENSXETP00000038203	ENSXETP00000028683	Interleukin 6 signal transducer.	ATP binding cassette subfamily A member 4.	0.993
IL6ST	clcf1	ENSXETP00000038203	ENSXETP00000001596	Interleukin 6 signal transducer.	Cardiotrophin-like cytokine factor 1.	0.922
IL6ST	npas4-2	ENSXETP00000038203	ENSXETP00000015873	Interleukin 6 signal transducer.	Neuronal PAS domain protein 4.	0.939
IL6ST	socs1	ENSXETP00000038203	ENSXETP00000053531	Interleukin 6 signal transducer.	Novel protein similar to suppressor of cytokine signaling 1.	0.425
IL6ST	socs3	ENSXETP00000038203	ENSXETP00000025441	Interleukin 6 signal transducer.	Suppressor of cytokine signaling 3.	0.578
IL6ST	socs3l	ENSXETP00000038203	ENSXETP00000009301	Interleukin 6 signal transducer.	Suppressor of cytokine signaling 3.	0.578
Il6	Cntf	ENSXETP00000024453	ENSXETP00000024819	Uncharacterized protein.	Uncharacterized protein.	0.578
Il6	ENSXETP00000022548	ENSXETP00000024453	ENSXETP00000022548	Uncharacterized protein.	IL12p40_C domain-containing protein.	0.495
Il6	IL6ST	ENSXETP00000024453	ENSXETP00000038203	Uncharacterized protein.	Interleukin 6 signal transducer.	0.996
Il6	LOC100496716	ENSXETP00000024453	ENSXETP00000036069	Uncharacterized protein.	Uncharacterized protein.	0.727

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