STRINGSTRING
efhc1 efhc1 pacrgl pacrgl fnta fnta spast spast setd2 setd2 fam110b fam110b tle4-2 tle4-2 tbcel tbcel DLEC1 DLEC1 TBCB TBCB tbce tbce dip2b dip2b LOC100495307 LOC100495307 racgap1.2 racgap1.2 INO80 INO80 OFD1 OFD1 dnal1 dnal1 washc1 washc1 pacrg pacrg fam110d fam110d racgap1 racgap1 efhc2 efhc2 FAM110C FAM110C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
efhc1Alkylglycerol monooxygenase. (544 aa)
pacrglUncharacterized protein. (230 aa)
fntaZinc finger CCHC-type containing 17. (379 aa)
spastSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (603 aa)
setd2H2A histone family member Y. (2971 aa)
fam110bAmyloid beta precursor protein binding family B member 2. (370 aa)
tle4-2Transducin like enhancer of split 4. (912 aa)
tbcelPatched 2. (438 aa)
DLEC1DLEC1 cilia and flagella associated protein. (1596 aa)
TBCBTubulin folding cofactor B. (246 aa)
tbceTubulin-specific chaperone e. (523 aa)
dip2bAnnexin A5. (1600 aa)
LOC100495307CAP-Gly domain-containing protein. (732 aa)
racgap1.2Bruton tyrosine kinase. (591 aa)
INO80INO80 complex ATPase subunit. (1547 aa)
OFD1OFD1 centriole and centriolar satellite protein. (749 aa)
dnal1Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). (201 aa)
washc1WASH complex subunit 1; Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Its assembly in the WASH core complex seems to inhibit its NPF activity and is required for its membrane targeting; Belongs to the WASH1 family. (472 aa)
pacrgIKAROS family zinc finger 3. (240 aa)
fam110dGlycine/arginine rich protein 1. (377 aa)
racgap1Uncharacterized protein. (632 aa)
efhc2Uncharacterized protein. (753 aa)
FAM110CFamily with sequence similarity 110 member C. (284 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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