STRINGSTRING
SLC9A4 SLC9A4 ENSXETP00000000644 ENSXETP00000000644 SLC39A8 SLC39A8 cldn17.3 cldn17.3 prcp prcp ABCC5 ABCC5 kcne3 kcne3 NOD1 NOD1 nt5dc3 nt5dc3 aqp9 aqp9 slc7a7 slc7a7 calhm1 calhm1 calhm3 calhm3 slc29a2 slc29a2 ENSXETP00000006444 ENSXETP00000006444 ldlrap1 ldlrap1 EGFR EGFR LOC100494782 LOC100494782 tmub2-2 tmub2-2 ITGB4 ITGB4 CD34 CD34 pdzd11 pdzd11 LOC100490322 LOC100490322 fam168b fam168b SLC3A2 SLC3A2 kcnq1 kcnq1 slc6a6 slc6a6 mlc1 mlc1 homer3 homer3 LOC100489360 LOC100489360 anxa1.3 anxa1.3 IDE IDE SLC4A11 SLC4A11 itga1 itga1 slc46a1 slc46a1 slc1a3 slc1a3 dlg1 dlg1 pkd1 pkd1 rhbg rhbg cog3 cog3 dhx34-2 dhx34-2 SLC4A5 SLC4A5 ORAI1 ORAI1 slc26a6 slc26a6 cask cask slc26a10 slc26a10 ENSXETP00000016950 ENSXETP00000016950 ceacam8 ceacam8 slc39a14 slc39a14 ENSXETP00000017180 ENSXETP00000017180 LOC101730286 LOC101730286 slc26a1 slc26a1 pianp pianp cul4a-2 cul4a-2 mttp.1 mttp.1 aqp7 aqp7 aqp3 aqp3 abcc10 abcc10 phldb1 phldb1 pdgfb-2 pdgfb-2 vsig1 vsig1 bscl2 bscl2 LOC100485738 LOC100485738 cldn8.1 cldn8.1 lin7b lin7b stxbp3 stxbp3 slc16a3 slc16a3 lin7c lin7c flot1 flot1 mttp.2 mttp.2 msn msn kcnj16 kcnj16 SPEF1 SPEF1 AQP10 AQP10 tgfa tgfa wasf2 wasf2 CA10 CA10 PHLDB3 PHLDB3 slc9a1 slc9a1 cdh17 cdh17 SLC4A9 SLC4A9 dstyk dstyk ezr ezr atg16l1 atg16l1 slc26a7 slc26a7 LOC100489930 LOC100489930 CA11 CA11 SLC51A SLC51A ATP7B ATP7B slc22a6 slc22a6 slc22a8 slc22a8 anxa1.1 anxa1.1 CLDN19 CLDN19 bsg bsg LOC100489522 LOC100489522 ajap1 ajap1 ENSXETP00000034825 ENSXETP00000034825 ENSXETP00000035147 ENSXETP00000035147 slc40a1 slc40a1 pkd2 pkd2 LOC100488346 LOC100488346 PALM PALM flot2 flot2 ENSXETP00000038003 ENSXETP00000038003 hpgd hpgd LOC100487834 LOC100487834 ENSXETP00000038817 ENSXETP00000038817 synj2bp synj2bp slc7a6 slc7a6 cldn11 cldn11 myo1c myo1c ITGA9 ITGA9 lin7a lin7a TEK TEK cldn1 cldn1 erbin erbin erlin2 erlin2 KCNJ4 KCNJ4 ABCC6 ABCC6 epcam epcam ctnnb1 ctnnb1 SLC7A1 SLC7A1 bsnd bsnd LOC100493583 LOC100493583 clrn1 clrn1 slc4a4 slc4a4 slc22a20p.1 slc22a20p.1 slc4a7 slc4a7 LOC100492908 LOC100492908 SLC19A1 SLC19A1 erbb2 erbb2 slc7a5 slc7a5 abcc3 abcc3 ERBB4 ERBB4 gon4l-2 gon4l-2 abcc12 abcc12 lepr lepr shroom4 shroom4 cxadr cxadr plpp3 plpp3 ITGA3 ITGA3 slc23a1 slc23a1 met met SLC10A1 SLC10A1 SLC26A5 SLC26A5 wnk3 wnk3 ABCC1 ABCC1 lrrc7 lrrc7 rhcg rhcg aqp4 aqp4 mst1r-2 mst1r-2 ERBB3 ERBB3 slc4a10 slc4a10 oscp1 oscp1 LOC101733960 LOC101733960 epb41 epb41 LOC100492274 LOC100492274
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (627 aa)
ENSXETP00000000644Uncharacterized protein. (423 aa)
SLC39A8Solute carrier family 39 member 8. (459 aa)
cldn17.3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
prcpUncharacterized protein. (496 aa)
ABCC5ATP binding cassette subfamily C member 5. (1437 aa)
kcne3Nebulin. (99 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (891 aa)
nt5dc35'-nucleotidase domain-containing protein 3; Belongs to the 5'(3')-deoxyribonucleotidase family. (567 aa)
aqp9SUMO specific peptidase 6; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
slc7a7Uncharacterized protein. (524 aa)
calhm1Uncharacterized protein. (337 aa)
calhm3Uncharacterized protein. (320 aa)
slc29a2Uncharacterized protein. (504 aa)
ENSXETP00000006444Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (175 aa)
ldlrap1Zinc finger protein 238, gene 2. (309 aa)
EGFRReceptor protein-tyrosine kinase. (1216 aa)
LOC100494782Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (598 aa)
tmub2-2Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (661 aa)
ITGB4Integrin beta. (1835 aa)
CD34Uncharacterized protein. (329 aa)
pdzd11PDZ domain-containing protein. (158 aa)
LOC100490322Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (297 aa)
fam168bMyelin-associated neurite-outgrowth inhibitor; Inhibitor of neuronal axonal outgrowth. Belongs to the FAM168 family. (226 aa)
SLC3A2Solute carrier family 3 member 2. (534 aa)
kcnq1KRI1 homolog; Belongs to the potassium channel family. (659 aa)
slc6a6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (622 aa)
mlc1Megalencephalic leukoencephalopathy with subcortical cysts 1 gene product. (377 aa)
homer3Rh-associated glycoprotein. (359 aa)
LOC100489360Uncharacterized protein. (328 aa)
anxa1.3Annexin. (350 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1016 aa)
SLC4A11Solute carrier family 4 member 11. (867 aa)
itga1Tetratricopeptide repeat domain 37; Belongs to the integrin alpha chain family. (1132 aa)
slc46a1Uncharacterized protein. (470 aa)
slc1a3Amino acid transporter. (542 aa)
dlg1Disks large homolog 1; Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction and cell proliferation (By similarity). (927 aa)
pkd1L-threonine dehydrogenase (pseudogene). (4091 aa)
rhbgAmmonium transporter Rh type B; Functions as a specific ammonium transporter; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (468 aa)
cog3Kidney mitochondrial carrier protein 1; Probable transporter; Belongs to the mitochondrial carrier (TC 2.A.29) family. (1005 aa)
dhx34-2DEAH-box helicase 34. (1501 aa)
SLC4A5Anion exchange protein. (1098 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (259 aa)
slc26a6STAS domain-containing protein. (737 aa)
caskWW domain binding protein 11; Belongs to the MAGUK family. (926 aa)
slc26a10Uncharacterized protein. (477 aa)
ENSXETP00000016950Uncharacterized protein. (409 aa)
ceacam8Lysophosphatidylcholine acyltransferase 2. (402 aa)
slc39a14Zinc transporter ZIP14; Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron. (470 aa)
ENSXETP00000017180Uncharacterized protein. (605 aa)
LOC101730286Fibroblast growth factor 3. (407 aa)
slc26a1Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (724 aa)
pianpAbhydrolase domain containing 13. (304 aa)
cul4a-2Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (572 aa)
mttp.1Solute carrier family 39 (zinc transporter), member 2. (931 aa)
aqp7Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (201 aa)
aqp3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (294 aa)
abcc10Small nuclear ribonucleoprotein, U5 200kDa subunit. (1501 aa)
phldb1Mdm1 nuclear protein. (1495 aa)
pdgfb-2Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
vsig1Uncharacterized protein. (356 aa)
bscl2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
LOC100485738Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (226 aa)
cldn8.1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (226 aa)
lin7bProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
stxbp3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (589 aa)
slc16a3Solute carrier family 16, member 3 (Monocarboxylic acid transporter 4). (473 aa)
lin7cProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
flot1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (444 aa)
mttp.2Vitellogenin domain-containing protein. (881 aa)
msnHomogentisate 1,2-dioxygenase. (591 aa)
kcnj16RNA binding motif protein X-linked. (412 aa)
SPEF1Sperm flagellar 1. (273 aa)
AQP10Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. (307 aa)
tgfaSolute carrier family 6 (neurotransmitter transporter), member 8 like. (163 aa)
wasf2Forkhead box Q1. (484 aa)
CA10Carbonic anhydrase 10; Belongs to the alpha-carbonic anhydrase family. (339 aa)
PHLDB3Pleckstrin homology like domain family B member 3. (633 aa)
slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (792 aa)
cdh17Retinol binding protein 3. (830 aa)
SLC4A9Anion exchange protein. (1027 aa)
dstykDual serine/threonine and tyrosine protein kinase; May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. May play a role in the embryonic development. (963 aa)
ezrFERM domain-containing protein. (621 aa)
atg16l1Autophagy-related protein 16; Plays an essential role in autophagy: interacts with ATG12- ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane; Belongs to the WD repeat ATG16 family. (622 aa)
slc26a7Anion exchange transporter. (613 aa)
LOC100489930Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (297 aa)
CA11Carbonic anhydrase 11; Belongs to the alpha-carbonic anhydrase family. (343 aa)
SLC51AOrganic solute transporter subunit alpha. (332 aa)
ATP7BATPase copper transporting beta. (1467 aa)
slc22a6RNA exonuclease 5. (554 aa)
slc22a8MFS domain-containing protein. (556 aa)
anxa1.1Annexin. (675 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
bsgSolute carrier family 25 member 13. (410 aa)
LOC100489522Uncharacterized protein. (309 aa)
ajap1Adherens junction-associated protein 1; May play a role in cell adhesion and cell migration. (390 aa)
ENSXETP00000034825Uncharacterized protein. (666 aa)
ENSXETP00000035147Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (533 aa)
slc40a1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (576 aa)
pkd2Ubiquitin carboxyl-terminal hydrolase 33. (951 aa)
LOC100488346Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1239 aa)
PALMParalemmin. (369 aa)
flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (479 aa)
ENSXETP00000038003Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (309 aa)
hpgdArmadillo repeat containing 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
LOC100487834Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (319 aa)
ENSXETP00000038817L27_1 domain-containing protein. (59 aa)
synj2bpSynj2bp protein. (145 aa)
slc7a6Y+L amino acid transporter 2; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family. (514 aa)
cldn11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (208 aa)
myo1cNucleolar protein 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1075 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1045 aa)
lin7aUncharacterized protein. (287 aa)
TEKTEK receptor tyrosine kinase. (1114 aa)
cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
erbinProline rich coiled-coil 2A. (1445 aa)
erlin2Erlin-2; Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Promotes sterol-accelerated ERAD of HMGCR. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway (By similarity); Belongs to the band 7/mec-2 family. (357 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (442 aa)
ABCC6Uncharacterized protein. (1505 aa)
epcamEpithelial cell adhesion molecule. (312 aa)
ctnnb1Dynactin subunit 5. (788 aa)
SLC7A1Solute carrier family 7 member 1. (654 aa)
bsndDistal membrane arm assembly complex 2. (307 aa)
LOC100493583Uncharacterized protein. (1286 aa)
clrn1Kelch like family member 17. (232 aa)
slc4a4Anion exchange protein. (1096 aa)
slc22a20p.1MFS domain-containing protein. (576 aa)
slc4a7Anion exchange protein. (1232 aa)
LOC100492908Uncharacterized protein; Belongs to the potassium channel family. (687 aa)
SLC19A1Solute carrier family 19 member 1. (538 aa)
erbb2Receptor protein-tyrosine kinase. (1316 aa)
slc7a5Dolichyl-phosphate mannosyltransferase polypeptide 3. (511 aa)
abcc3Septin 9. (1544 aa)
ERBB4Receptor protein-tyrosine kinase. (1291 aa)
gon4l-2Uncharacterized protein. (676 aa)
abcc12Uncharacterized protein. (1298 aa)
leprLeucine-rich repeat-containing protein 42. (1138 aa)
shroom4Splicing factor 3b subunit 5. (1721 aa)
cxadrUncharacterized protein. (362 aa)
plpp3Ppap2b protein. (307 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1046 aa)
slc23a1Radial spoke head protein 6 homolog A. (584 aa)
metUTP6 small subunit processome component. (1402 aa)
SLC10A1Solute carrier family 10 member 1. (346 aa)
SLC26A5Solute carrier family 26 member 5. (803 aa)
wnk3Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
ABCC1ATP binding cassette subfamily C member 1. (1516 aa)
lrrc7Densin-180. (1388 aa)
rhcgAmmonium transporter Rh type C; Functions as an ammonia transporter. (488 aa)
aqp4Peptidylprolyl isomerase like 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (318 aa)
mst1r-2Fasciculation and elongation protein zeta 1. (1368 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1347 aa)
slc4a10Anion exchange protein. (1187 aa)
oscp1Uncharacterized protein. (380 aa)
LOC101733960Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (285 aa)
epb41Membrane associated guanylate kinase, WW and PDZ domain containing 2. (854 aa)
LOC100492274Uncharacterized protein. (521 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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