STRINGSTRING
ddit3 ddit3 WNT1 WNT1 zfpm2 zfpm2 sav1 sav1 RREB1 RREB1 zfp36 zfp36 asxl2 asxl2 ptgs2 ptgs2 zbtb7c zbtb7c adipoq adipoq creb1 creb1 cmklr1 cmklr1 zadh2 zadh2 pparg pparg e2f1 e2f1 BBS12 BBS12 wif1 wif1 tph1 tph1 xbp1 xbp1 jag1 jag1 cep112 cep112 kalrn kalrn sirt6 sirt6 sfrp2 sfrp2 lrp5 lrp5 axin1 axin1 zfp36l2 zfp36l2 tgfb1 tgfb1 wwtr1 wwtr1 ENSXETP00000021848 ENSXETP00000021848 CARM1 CARM1 rorc rorc zbtb16 zbtb16 crebl2 crebl2 LOC734009 LOC734009 ccdc85b ccdc85b SIRT2 SIRT2 nr1d1 nr1d1 zbtb7b zbtb7b syap1 syap1 KLF5 KLF5 arntl arntl rarres2 rarres2 metrnl metrnl flcn flcn stk3 stk3 trio trio MMP11 MMP11 rora rora znf534 znf534 lep lep dusp10.2 dusp10.2 zfp36l1 zfp36l1 noct noct SORT1 SORT1 WDFY2 WDFY2 yap1 yap1 cebpb cebpb dusp10 dusp10 htr2a htr2a ptprq ptprq MEDAG MEDAG LOC733544 LOC733544 fndc3b fndc3b gper1 gper1 gata3 gata3 phkg2-2 phkg2-2 ccdc71l ccdc71l zfpm1 zfpm1 sirt1 sirt1 NAPEPLD NAPEPLD idi1-2 idi1-2 Zc3h12a Zc3h12a carm1p1 carm1p1 TMEM64 TMEM64
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ddit3Potassium channel, voltage gated subfamily E regulatory beta subunit 3. (209 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
zfpm2GPI mannosyltransferase 1. (1151 aa)
sav1Salvador homolog 1 (Drosophila). (388 aa)
RREB1Ras responsive element binding protein 1. (1688 aa)
zfp36Zfp36 protein. (313 aa)
asxl2NIPA-like domain containing 1. (1455 aa)
ptgs2EGF-like domain-containing protein. (619 aa)
zbtb7cATPase, Na+/K+ transporting, alpha 2 polypeptide. (585 aa)
adipoqCollagen, type VII, alpha 1 (Epidermolysis bullosa, dystrophic, dominant and recessive). (235 aa)
creb1DET1, COP1 ubiquitin ligase partner. (341 aa)
cmklr1UDP-N-acetylhexosamine pyrophosphorylase-like protein 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
zadh2Zinc binding alcohol dehydrogenase, domain containing 2. (399 aa)
ppargPeroxisome proliferator activated receptor gamma. (327 aa)
e2f1TEA domain family member 1 (SV40 transcriptional enhancer factor). (428 aa)
BBS12Bardet-Biedl syndrome 12. (676 aa)
wif1Hypoxia inducible factor 1 subunit alpha inhibitor. (393 aa)
tph1Trace amine associated receptor 2 (gene/pseudogene). (494 aa)
xbp1Destrin, actin depolymerizing factor. (349 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
cep112Adenosine monophosphate deaminase 2. (310 aa)
kalrnSolute carrier family 7 member 11. (2463 aa)
sirt6Sirtuin (Silent mating type information regulation 2 homolog) 6. (331 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
axin1P21 protein (Cdc42/Rac)-activated kinase 3. (877 aa)
zfp36l2mRNA decay activator protein ZFP36L2; Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis (By similarity). Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery (By similarity). Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-con [...] (362 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
wwtr1WW domain containing transcription regulator 1. (390 aa)
ENSXETP00000021848Uncharacterized protein. (59 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (602 aa)
rorcNR LBD domain-containing protein. (397 aa)
zbtb16Collagen, type IX, alpha 3. (660 aa)
crebl2cAMP-responsive element-binding protein-like 2; Probable regulator of creb1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle (By similarity); Belongs to the bZIP family. ATF subfamily. (128 aa)
LOC734009Uncharacterized protein. (347 aa)
ccdc85bUncharacterized protein. (201 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (414 aa)
nr1d1Heparan sulfate 6-O-sulfotransferase 3. (529 aa)
zbtb7bMonoacylglycerol O-acyltransferase 2, gene 1. (476 aa)
syap1Synapse associated protein 1, SAP47 homolog. (364 aa)
KLF5Kruppel like factor 5. (434 aa)
arntlSin3A associated protein 18kDa. (513 aa)
rarres2Uncharacterized protein. (165 aa)
metrnlUncharacterized protein. (291 aa)
flcnFolliculin; Belongs to the folliculin family. (579 aa)
stk3Elongator acetyltransferase complex subunit 4. (498 aa)
trioNotochord homeobox. (3081 aa)
MMP11Matrix metallopeptidase 11. (478 aa)
roraPotassium channel, two pore domain subfamily K, member 4. (518 aa)
znf534Uncharacterized protein. (423 aa)
lepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
dusp10.2Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
zfp36l1Uncharacterized protein. (345 aa)
noctCCR4 carbon catabolite repression 4-like (S. cerevisiae). (458 aa)
SORT1Sortilin. (801 aa)
WDFY2WD repeat and FYVE domain containing 2. (404 aa)
yap1Uncharacterized protein. (487 aa)
cebpbCCAAT/enhancer binding protein (C/EBP), beta. (145 aa)
dusp10NPC1 like 1. (464 aa)
htr2aSolute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29. (483 aa)
ptprqAsparaginyl-tRNA synthetase 2, mitochondrial. (2205 aa)
MEDAGMesenteric estrogen dependent adipogenesis. (307 aa)
LOC733544BCL11A, BAF complex component. (254 aa)
fndc3bDermatopontin. (1205 aa)
gper1Tripartite motif containing 55; Belongs to the G-protein coupled receptor 1 family. (361 aa)
gata3Uncharacterized protein. (454 aa)
phkg2-2Lines homolog 1. (358 aa)
ccdc71lATPase, class VI, type 11C. (214 aa)
zfpm1C-terminal Src kinase. (1214 aa)
sirt1Thrombospondin-type laminin G domain and EAR repeats. (707 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (440 aa)
idi1-2Isopentenyl-diphosphate delta isomerase 1. (290 aa)
Zc3h12aC3H1-type domain-containing protein. (349 aa)
carm1p1CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (479 aa)
TMEM64Transmembrane protein 64. (315 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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