STRINGSTRING
HYAL1 HYAL1 anapc5 anapc5 adcy7-2 adcy7-2 ythdc2 ythdc2 ENSXETP00000000702 ENSXETP00000000702 edn1 edn1 atad5 atad5 GLI1 GLI1 dync1li1 dync1li1 ANKRD17 ANKRD17 mad2l1bp mad2l1bp smpd5l smpd5l ndc80 ndc80 CCDC57 CCDC57 cul4a cul4a nsmce2 nsmce2 msx1 msx1 tfdp1 tfdp1 stox1 stox1 med1l med1l KIF14 KIF14 tpr tpr mtbp mtbp mad2l1 mad2l1 mad1l1 mad1l1 cenpv cenpv dbf4b dbf4b npm2 npm2 bcl2l11 bcl2l11 DDR2 DDR2 kif23 kif23 pbk pbk rap1b rap1b arl4a-2 arl4a-2 sass6.2 sass6.2 anxa1.3 anxa1.3 map3k20 map3k20 ncapg ncapg BTC BTC LOC105946289 LOC105946289 plk4 plk4 ttl ttl CSPP1 CSPP1 SMC5 SMC5 anapc7 anapc7 CCPG1 CCPG1 mecp2 mecp2 brca2 brca2 pkd1 pkd1 cdc16 cdc16 cpsf3 cpsf3 pagr1 pagr1 ENSXETP00000015534 ENSXETP00000015534 cit cit rrm2b rrm2b ddr2l ddr2l gipc1 gipc1 racgap1 racgap1 cdca5 cdca5 spdyc spdyc chek2 chek2 cks1b cks1b mepce mepce plrg1 plrg1 lrp5 lrp5 pdgfb-2 pdgfb-2 arhgap26 arhgap26 nup133 nup133 CXCR5 CXCR5 cul3 cul3 fgf8 fgf8 smc2 smc2 macroh2a1 macroh2a1 rgcc rgcc tbx3 tbx3 CCNT2 CCNT2 mapk15 mapk15 ccndx ccndx psmd10 psmd10 numa1 numa1 anapc11 anapc11 LRP6 LRP6 E2F7 E2F7 ATRX ATRX cdc25a cdc25a igf2 igf2 FBXO42 FBXO42 ddx11 ddx11 slf2 slf2 pcid2 pcid2 il10 il10 gpsm2 gpsm2 cdc6 cdc6 dusp3 dusp3 rad51c rad51c DRD2 DRD2 FOSL1 FOSL1 F7ANK9_XENTR F7ANK9_XENTR SIRT2 SIRT2 ccnd1 ccnd1 e2f8 e2f8 cdc25b cdc25b app app rptor rptor LOC101734301 LOC101734301 slf1 slf1 zbed6cl zbed6cl cep295 cep295 slc25a42 slc25a42 ppp1r10 ppp1r10 tgfa tgfa cdc27 cdc27 klhl18 klhl18 LSM11 LSM11 CCNT1 CCNT1 xrcc3 xrcc3 mrpl15-2 mrpl15-2 ccnyl1 ccnyl1 stxbp4 stxbp4 slc6a4 slc6a4 GEN1 GEN1 CCNY CCNY ube2c ube2c CDT1 CDT1 CDC14A CDC14A LOC100488959 LOC100488959 epgn epgn ereg ereg CDK5R1 CDK5R1 wiz wiz spdya spdya anxa1.1 anxa1.1 zpr1 zpr1 LOC100497395 LOC100497395 dbf4 dbf4 cited2 cited2 tent2 tent2 rad51c-2 rad51c-2 RCC2 RCC2 mblac1 mblac1 stil stil ncaph ncaph NR2E1 NR2E1 cdk1 cdk1 cdc42 cdc42 SMC4 SMC4 NCAPG2 NCAPG2 cdc73 cdc73 poldip2 poldip2 pkd2 pkd2 spag5 spag5 Rskr Rskr rb1 rb1 ranbp1 ranbp1 cks2 cks2 cul4b cul4b adam17 adam17 trim32 trim32 FAM83D FAM83D nudt16 nudt16 UBXN2B UBXN2B smpd3 smpd3 svil svil LOC100498128 LOC100498128 rrm2.2 rrm2.2 rrm2.1 rrm2.1 mnat1 mnat1 lgmn lgmn ect2 ect2 aurkb aurkb chek1 chek1 THOC1 THOC1 ENSXETP00000045156 ENSXETP00000045156 rhno1 rhno1 banp banp gipc2 gipc2 rrm1 rrm1 chd7 chd7 thumpd2-2 thumpd2-2 KMT2E KMT2E cep120 cep120 rock2 rock2 meioc meioc bub1-2 bub1-2 cdc23 cdc23 cdc25c cdc25c usp19 usp19 nkx3-1 nkx3-1 ccnk ccnk SLC6A4 SLC6A4 map10 map10 cdc14b cdc14b sass6 sass6 cdc7 cdc7 racgap1.2 racgap1.2 ENSXETP00000052180 ENSXETP00000052180 il1b il1b gipc3 gipc3 lsm10 lsm10 ENSXETP00000052591 ENSXETP00000052591 foxo4 foxo4 amdhd2-2 amdhd2-2 foxg1 foxg1 INO80 INO80
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HYAL1Hyaluronidase. (753 aa)
anapc5ANAPC5 domain-containing protein. (743 aa)
adcy7-2Adenylate cyclase 7. (180 aa)
ythdc2Serine/threonine-protein kinase Sgk1. (1419 aa)
ENSXETP00000000702Uncharacterized protein. (77 aa)
edn1Nidogen 2. (222 aa)
atad5Dipeptidyl-peptidase 6. (1728 aa)
GLI1GLI family zinc finger 1. (1371 aa)
dync1li1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (529 aa)
ANKRD17Ankyrin repeat domain 17. (2605 aa)
mad2l1bpPoly(ADP-ribose) polymerase family member 6. (247 aa)
smpd5lUncharacterized protein. (523 aa)
ndc80Kinetochore protein NDC80 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores t [...] (640 aa)
CCDC57Coiled-coil domain containing 57. (908 aa)
cul4aCULLIN_2 domain-containing protein; Belongs to the cullin family. (769 aa)
nsmce2Ring finger protein 34, E3 ubiquitin protein ligase. (203 aa)
msx1Potassium channel, two pore domain subfamily K, member 18. (275 aa)
tfdp1Transcription factor. (411 aa)
stox1Disks large homolog 1. (977 aa)
med1lMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (678 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1411 aa)
tprSOS Ras/Rho guanine nucleotide exchange factor 2. (2324 aa)
mtbpMdm2-binding protein; May play a role in mdm2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of mdm2, thereby enhancing mdm2 stability. This promotes mdm2-mediated ubiquitination of p53/TP53 and its subsequent degradation (By similarity). (867 aa)
mad2l1PIF1 5'-to-3' DNA helicase. (203 aa)
mad1l1Neutrophil cytosolic factor 4. (605 aa)
cenpvCyclin and CBS domain divalent metal cation transport mediator 2. (232 aa)
dbf4bDBF4-type domain-containing protein. (836 aa)
npm2Nucleoplasmin domain-containing protein. (203 aa)
bcl2l11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (194 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (856 aa)
kif23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (970 aa)
pbkPDZ binding kinase. (325 aa)
rap1bRas-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. (184 aa)
arl4a-2ADP ribosylation factor like GTPase 4A. (296 aa)
sass6.2Uncharacterized protein. (639 aa)
anxa1.3Annexin. (350 aa)
map3k20Uncharacterized protein. (790 aa)
ncapgProtein tyrosine phosphatase non-receptor type 9. (1041 aa)
BTCBetacellulin. (170 aa)
LOC105946289Protein kinase domain-containing protein. (307 aa)
plk4Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as sass6, cenpj/cpap, ccp110, cep135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Its central role in centriole replication suggests a possible role in tumorigenes [...] (946 aa)
ttlTtl protein. (377 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1284 aa)
SMC5Structural maintenance of chromosomes 5. (1069 aa)
anapc7Cyclin E1. (590 aa)
CCPG1Cell cycle progression 1. (873 aa)
mecp2Kruppel-like factor 17. (466 aa)
brca2StAR related lipid transfer domain containing 9. (3138 aa)
pkd1L-threonine dehydrogenase (pseudogene). (4091 aa)
cdc16TPR_REGION domain-containing protein. (612 aa)
cpsf3Uncharacterized protein. (692 aa)
pagr1Uncharacterized protein. (212 aa)
ENSXETP00000015534Uncharacterized protein. (248 aa)
citCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)
rrm2bUncharacterized protein. (416 aa)
ddr2lDiscoidin domain receptor family, member 2. (879 aa)
gipc1GIPC PDZ domain containing family, member 1. (332 aa)
racgap1Uncharacterized protein. (632 aa)
cdca5LOC100145078 protein. (274 aa)
spdycWASH complex subunit 4. (369 aa)
chek2GDNF family receptor alpha-like. (504 aa)
cks1bCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa)
mepceVon Hippel-Lindau binding protein 1. (490 aa)
plrg1Signal transducing adaptor molecule. (543 aa)
lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
pdgfb-2Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
arhgap26Rho GTPase-activating protein 26; GTPase-activating protein for rhoa and cdc42. (771 aa)
nup133Nucleoporin 133kDa. (245 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
cul3Cullin-3; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity). Involved in ER- Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division (By similarity). May play a role in the regulation of mittotic entry via ubiquitinati [...] (770 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
smc2Structural maintenance of chromosomes protein. (1225 aa)
macroh2a1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
rgccDual specificity phosphatase 11 (RNA/RNP complex 1-interacting), gene 2. (128 aa)
tbx3T-box 3. (701 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (771 aa)
mapk15Mitogen-activated protein kinase. (590 aa)
ccndxNovel cyclin; Belongs to the cyclin family. (290 aa)
psmd10Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10. (227 aa)
numa1Kynurenine aminotransferase 3. (2351 aa)
anapc11Guanine nucleotide binding protein (G protein), beta polypeptide 1-like. (84 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1622 aa)
E2F7Transcription factor E2F7; Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells. Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'. Directly represses transcription of classical E2F transcription factors such as e2f1. Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC- 3' and mediating repression of G1/S-regulated genes. Acts as a promoter of sprouting angiogenes [...] (872 aa)
ATRXATRX chromatin remodeler. (2268 aa)
cdc25aMannosidase, alpha, class 2B, member 1. (527 aa)
igf2IlGF domain-containing protein. (217 aa)
FBXO42F-box protein 42. (672 aa)
ddx11Carnitine O-acetyltransferase b. (899 aa)
slf2Olfactory receptor family 2 subfamily B member 2. (845 aa)
pcid2Novel protein, containing PCI domain. (399 aa)
il10Activating transcription factor 6. (172 aa)
gpsm2Ribonucleotide reductase M1. (663 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (595 aa)
dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
rad51cMalignant T-cell-amplified sequence 1. (369 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (440 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (298 aa)
F7ANK9_XENTRN-acetyltransferase domain-containing protein. (241 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (414 aa)
ccnd1Uncharacterized protein; Belongs to the cyclin family. (267 aa)
e2f8Transcription factor E2F8; Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells. Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'. Directly represses transcription of classical E2F transcription factors such as e2f1. Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC- 3' and mediating repression of G1/S-regulated genes. Acts as a promoter of sprouting angiogenes [...] (744 aa)
cdc25bRhodanese domain-containing protein. (560 aa)
appGeneral transcription factor IIE subunit 2. (769 aa)
rptorWD_REPEATS_REGION domain-containing protein. (1356 aa)
LOC101734301STAM binding protein like 1. (365 aa)
slf1Teratocarcinoma-derived growth factor 1, member 3. (910 aa)
zbed6clFatty acyl-CoA reductase 1. (993 aa)
cep295ALMS_motif domain-containing protein. (1783 aa)
slc25a42Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate. (332 aa)
ppp1r10Proteasome 26S subunit, ATPase 6. (844 aa)
tgfaSolute carrier family 6 (neurotransmitter transporter), member 8 like. (163 aa)
cdc27Phosphodiesterase 11A. (845 aa)
klhl18BTB domain-containing protein. (583 aa)
LSM11LSM11, U7 small nuclear RNA associated. (267 aa)
CCNT1CYCLIN domain-containing protein; Belongs to the cyclin family. (631 aa)
xrcc3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (348 aa)
mrpl15-2Mitochondrial ribosomal protein L15. (290 aa)
ccnyl1Cyclin-Y-like protein 1; Belongs to the cyclin family. Cyclin Y subfamily. (347 aa)
stxbp4Uncharacterized protein. (516 aa)
slc6a4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (592 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (927 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
ube2cMyotubularin related protein 2; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
CDT1Chromatin licensing and DNA replication factor 1. (617 aa)
CDC14ACell division cycle 14A. (575 aa)
LOC100488959Pumilio RNA binding family member 3. (856 aa)
epgnLeucine-rich repeats and calponin homology (CH) domain containing 1. (138 aa)
eregNIMA-related kinase 6. (156 aa)
CDK5R1Cyclin dependent kinase 5 regulatory subunit 1. (292 aa)
wizUncharacterized protein. (1823 aa)
spdyaLOC100127607 protein. (309 aa)
anxa1.1Annexin. (675 aa)
zpr1Uncharacterized protein. (446 aa)
LOC100497395Rhodanese domain-containing protein. (413 aa)
dbf4Protein DBF4 homolog A; Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Not required during the initiation of DNA replication in egg and during early embryonic development but is required later throughout development. The complex cdc7-dbf4a phosphorylates mcm2 subunit (By similarity). (663 aa)
cited2Cbp/p300-interacting transactivator 2; Transcriptional coactivator or corepressor of the p300/CBP- mediated transcription complex. May be involved in sex determination, early gonad development, left-right patterning during embryogenesis and differentiation of the adrenal cortex (By similarity); Belongs to the CITED family. (281 aa)
tent2Poly(A) RNA polymerase GLD2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs during oocyte maturation. Plays a central role during oocyte maturation by mediating polyadenylation of dormant mRNAs, which contain 5'AAUAAA-3' sequence in their 3'-UTR. In immature oocytes, polyadenylation of poly(A) tails is counteracted by the ribonuclease parn. During maturation parn is excluded from the ribonucleoprote [...] (492 aa)
rad51c-2RECA_2 domain-containing protein. (121 aa)
RCC2Regulator of chromosome condensation 2. (447 aa)
mblac1Transglutaminase 1. (226 aa)
stilUncharacterized protein. (1282 aa)
ncaphCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (704 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (397 aa)
cdk1Cell division cycle 2, G1 to S and G2 to M; Belongs to the protein kinase superfamily. (302 aa)
cdc42Uncharacterized protein. (212 aa)
SMC4Structural maintenance of chromosomes protein. (1305 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1152 aa)
cdc73Hyperparathyroidism 2 (With jaw tumor). (531 aa)
poldip2Serine hydrolase-like (pseudogene). (403 aa)
pkd2Ubiquitin carboxyl-terminal hydrolase 33. (951 aa)
spag5Interferon induced, with helicase C domain 1. (1498 aa)
RskrProtein kinase domain-containing protein. (180 aa)
rb1Uncharacterized protein. (914 aa)
ranbp1RAN binding protein 1. (209 aa)
cks2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
cul4bDNL-type zinc finger; Belongs to the cullin family. (872 aa)
adam17Monooxygenase, DBH-like 2, pseudogene. (834 aa)
trim32LOC100124994 protein. (649 aa)
FAM83DFamily with sequence similarity 83 member D. (560 aa)
nudt16Solute carrier family 45 member 2. (213 aa)
UBXN2BUBX domain protein 2B. (351 aa)
smpd3Barttin CLCNK-type chloride channel accessory beta subunit. (659 aa)
svilCoiled-coil domain containing 181. (2279 aa)
LOC100498128Gamma-aminobutyric acid (GABA) A receptor, alpha 6. (293 aa)
rrm2.2Collagen, type VI, alpha 6. (447 aa)
rrm2.1Uncharacterized protein. (397 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
lgmnProtein phosphatase 1 regulatory subunit 9A. (433 aa)
ect2Survival of motor neuron 1. (987 aa)
aurkbAurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] (375 aa)
chek1Basonuclin 2; Belongs to the protein kinase superfamily. (474 aa)
THOC1THO complex 1. (671 aa)
ENSXETP00000045156Uncharacterized protein. (197 aa)
rhno1Uncharacterized protein. (253 aa)
banpProtein BANP; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). Belongs to the BANP/SMAR1 family. (510 aa)
gipc2Solute carrier family 4, sodium bicarbonate cotransporter, member 7. (333 aa)
rrm1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (786 aa)
chd7Chromodomain helicase DNA-binding protein 7. (256 aa)
thumpd2-2THUMP domain containing 2. (4637 aa)
KMT2ELysine methyltransferase 2E. (1800 aa)
cep120Centrosomal protein of 120 kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome; Belongs to the CEP120 family. (974 aa)
rock2Mediator of RNA polymerase II transcription subunit 18; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1461 aa)
meiocUncharacterized protein. (801 aa)
bub1-2Tumor necrosis factor alpha-induced protein 8. (748 aa)
cdc23Serine/threonine kinase 36. (604 aa)
cdc25cRhodanese domain-containing protein. (589 aa)
usp19Uncharacterized protein. (1465 aa)
nkx3-1Homeobox domain-containing protein. (211 aa)
ccnkUncharacterized protein; Belongs to the cyclin family. (659 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (666 aa)
map10Rab2b, member RAS oncogene family. (815 aa)
cdc14bUncharacterized protein. (514 aa)
sass6Transmembrane and tetratricopeptide repeat containing 4. (661 aa)
cdc7AT-rich interaction domain 1A. (557 aa)
racgap1.2Bruton tyrosine kinase. (591 aa)
ENSXETP00000052180Uncharacterized protein. (77 aa)
il1bInterleukin-1; Belongs to the IL-1 family. (286 aa)
gipc3PDZ domain-containing protein. (338 aa)
lsm10LSM10, U7 small nuclear RNA associated. (121 aa)
ENSXETP00000052591Uncharacterized protein. (78 aa)
foxo4Forkhead box O4. (68 aa)
amdhd2-2Amidohydrolase domain containing 2. (78 aa)
foxg1Myb-related transcription factor, partner of profilin. (432 aa)
INO80INO80 complex ATPase subunit. (1547 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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