STRINGSTRING
LAMA4 LAMA4 INO80 INO80 INO80D INO80D racgap1.2 racgap1.2 lama3 lama3 lama2 lama2 dr1 dr1 nfe2l2 nfe2l2 mbip mbip WNT2 WNT2 kat14 kat14 mcrs1 mcrs1 seh1l-2 seh1l-2 rack1 rack1 WNT2B WNT2B ctnnb1 ctnnb1 dag1 dag1 b4galt6 b4galt6 tada2a tada2a zzz3 zzz3 noct noct LOC101731073 LOC101731073 tfpt tfpt crb2 crb2 lamtor5 lamtor5 WDPCP WDPCP DHX36 DHX36 yeats2 yeats2 dll1 dll1 PHLDB3 PHLDB3 ino80e ino80e dlc dlc wnt11-2 wnt11-2 tdg tdg ruvbl1 ruvbl1 phldb1 phldb1 sfrp2 sfrp2 rbm19 rbm19 jag1 jag1 racgap1 racgap1 bag6 bag6 tenm4 tenm4 NIPBL NIPBL actr8 actr8 sgf29 sgf29 NR2C2 NR2C2 ruvbl2 ruvbl2 rab14 rab14 trip12 trip12 UCHL5 UCHL5 LAMA1 LAMA1 WNT1 WNT1 LAMA5 LAMA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LAMA4Laminin subunit alpha 4. (1678 aa)
INO80INO80 complex ATPase subunit. (1547 aa)
INO80DINO80 complex subunit D. (1024 aa)
racgap1.2Bruton tyrosine kinase. (591 aa)
lama3Ribulose-5-phosphate-3-epimerase. (2946 aa)
lama2WD repeat and coiled-coil-containing protein. (3099 aa)
dr1Down-regulator of transcription 1, TBP-binding (Negative cofactor 2). (175 aa)
nfe2l2Similar to nfe2l2 (Nuclear factor (Erythroid-derived 2)-like 2). (589 aa)
mbipUncharacterized protein. (330 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
kat14CSRP2 binding protein. (776 aa)
mcrs1Microspherule protein 1. (453 aa)
seh1l-2Nucleoporin SEH1. (112 aa)
rack1Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1. (317 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
ctnnb1Dynactin subunit 5. (788 aa)
dag1Peptidase S72 domain-containing protein. (885 aa)
b4galt6Arachidonate 15-lipoxygenase, type B. (393 aa)
tada2aTranscriptional adapter. (473 aa)
zzz3Exostosin-like glycosyltransferase 2. (886 aa)
noctCCR4 carbon catabolite repression 4-like (S. cerevisiae). (458 aa)
LOC101731073Uncharacterized protein. (233 aa)
tfptTCF3 (E2A) fusion partner. (252 aa)
crb2EMI domain containing 1. (1456 aa)
lamtor5Ragulator complex protein LAMTOR5; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). (91 aa)
WDPCPWD repeat containing planar cell polarity effector. (708 aa)
DHX36DEAH-box helicase 36. (1006 aa)
yeats2Dynein axonemal assembly factor 4. (1245 aa)
dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (740 aa)
PHLDB3Pleckstrin homology like domain family B member 3. (633 aa)
ino80eUncharacterized protein. (241 aa)
dlcDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
wnt11-2Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Shares much functionality with wnt11b. Signals through a non-canonical Wnt pathway to activate Jun-N- terminal kinase (JNK) to regulate gastrulation movements. Acts in a non-cell-autonomous manner to control neural crest migration, probably acting as an extracellular signal from surrounding tissue, but is not required for neural crest induction. Acts redundantly with wnt11b during pronephros induction. Regulates cardiac morphogenesis through the activation of JNK, but is not requ [...] (352 aa)
tdgUDG domain-containing protein. (459 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
phldb1Mdm1 nuclear protein. (1495 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
rbm19High mobility group nucleosomal binding domain 2. (920 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
racgap1Uncharacterized protein. (632 aa)
bag6Large proline-rich protein bag6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the bag6/bat3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1135 aa)
tenm4Uncharacterized protein. (2596 aa)
NIPBLNipped-B protein. (2938 aa)
actr8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (193 aa)
sgf29Pseudouridine synthase like 1. (269 aa)
NR2C2Nuclear receptor subfamily 2 group C member 2. (659 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (470 aa)
rab14Uncharacterized protein. (214 aa)
trip12E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins. Acts as a key regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spr [...] (2064 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
LAMA1Laminin subunit alpha 1. (3101 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
LAMA5Laminin subunit alpha 5. (3235 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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