(18 nodes) Regulation of activated T cell proliferation network (Xenopus tropicalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lrrc1	Uncharacterized protein. (508 aa)
	ENSXETP00000000456	Uncharacterized protein. (198 aa)
	lrrc32.1	5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled. (666 aa)
	il27ra	Uncharacterized protein. (473 aa)
	LOC100490493	Coiled-coil-helix-coiled-coil-helix domain containing 2; Belongs to the protein kinase superfamily. (421 aa)
	igf3	Aldehyde dehydrogenase 1 family member B1. (126 aa)
	polr3b-2	Uncharacterized protein. (271 aa)
	SCRIB	Scribble planar cell polarity protein. (945 aa)
	hhla2	Uncharacterized protein. (377 aa)
	ENSXETP00000022548	IL12p40_C domain-containing protein. (249 aa)
	igf2	IlGF domain-containing protein. (217 aa)
	pycard	Family with sequence similarity 84 member B. (199 aa)
	fadd	Zinc finger, NFX1-type containing 1, gene 2. (188 aa)
	LOC100490663	Uncharacterized protein; Belongs to the protein kinase superfamily. (439 aa)
	rps3	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (246 aa)
	LOC100496716	Uncharacterized protein. (195 aa)
	tspan2-2	Adaptor related protein complex 1 subunit mu 1. (634 aa)
	RC3H1	Ring finger and CCCH-type domains 1. (1123 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXETP00000000456	LOC100496716	ENSXETP00000000456	ENSXETP00000036069	Uncharacterized protein.	Uncharacterized protein.	0.450
ENSXETP00000022548	LOC100496716	ENSXETP00000022548	ENSXETP00000036069	IL12p40_C domain-containing protein.	Uncharacterized protein.	0.471
LOC100490493	fadd	ENSXETP00000005197	ENSXETP00000025713	Coiled-coil-helix-coiled-coil-helix domain containing 2; Belongs to the protein kinase superfamily.	Zinc finger, NFX1-type containing 1, gene 2.	0.908
LOC100490663	fadd	ENSXETP00000026178	ENSXETP00000025713	Uncharacterized protein; Belongs to the protein kinase superfamily.	Zinc finger, NFX1-type containing 1, gene 2.	0.908
LOC100496716	ENSXETP00000000456	ENSXETP00000036069	ENSXETP00000000456	Uncharacterized protein.	Uncharacterized protein.	0.450
LOC100496716	ENSXETP00000022548	ENSXETP00000036069	ENSXETP00000022548	Uncharacterized protein.	IL12p40_C domain-containing protein.	0.471
LOC100496716	pycard	ENSXETP00000036069	ENSXETP00000023894	Uncharacterized protein.	Family with sequence similarity 84 member B.	0.450
fadd	LOC100490493	ENSXETP00000025713	ENSXETP00000005197	Zinc finger, NFX1-type containing 1, gene 2.	Coiled-coil-helix-coiled-coil-helix domain containing 2; Belongs to the protein kinase superfamily.	0.908
fadd	LOC100490663	ENSXETP00000025713	ENSXETP00000026178	Zinc finger, NFX1-type containing 1, gene 2.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.908
pycard	LOC100496716	ENSXETP00000023894	ENSXETP00000036069	Family with sequence similarity 84 member B.	Uncharacterized protein.	0.450

Server load: low (18%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2025

Credits

Access

Info

About