STRINGSTRING
tnf tnf hba1-2 hba1-2 LOC101733520 LOC101733520 taok2 taok2 NOD1 NOD1 edar edar sh3rf3 sh3rf3 traf5 traf5 map2k7 map2k7 ncf1 ncf1 ENSXETP00000011099 ENSXETP00000011099 ripk1 ripk1 SERPINF2 SERPINF2 dixdc1 dixdc1 rb1cc1 rb1cc1 TNFSF11 TNFSF11 tpm3 tpm3 tirap tirap LOC100491693 LOC100491693 cirbp-2 cirbp-2 sh3rf2 sh3rf2 tlr3 tlr3 ankrd6 ankrd6 wnt11-2 wnt11-2 znf622 znf622 ENSXETP00000021784 ENSXETP00000021784 wnt7b wnt7b pycard pycard LOC100487218 LOC100487218 ENSXETP00000000456 ENSXETP00000000456 TRAF2 TRAF2 eda2r eda2r app app ska1-2 ska1-2 flt4 flt4 sh3rf1 sh3rf1 TPD52L1 TPD52L1 ENSXETP00000033383 ENSXETP00000033383 fgf19 fgf19 traf6 traf6 traf4 traf4 gadd45g gadd45g traf1 traf1 TNIK TNIK pja2 pja2 LOC108645626 LOC108645626 LOC733866 LOC733866 ENSXETP00000043337 ENSXETP00000043337 naip naip ENSXETP00000043412 ENSXETP00000043412 nrk nrk mink1 mink1 dusp19 dusp19 map2k4 map2k4 traf3 traf3 mbip mbip wnt16 wnt16 taok1 taok1 card9 card9 RIPK2 RIPK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tnfThyrotropin-releasing hormone receptor 3. (227 aa)
hba1-2Protein kinase domain-containing protein. (102 aa)
LOC101733520C-C motif chemokine. (91 aa)
taok2Prune homolog 2. (1083 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (891 aa)
edarEctodysplasin A receptor. (451 aa)
sh3rf3Ornithine decarboxylase 1. (875 aa)
traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (539 aa)
map2k7TBC1 domain family member 23. (470 aa)
ncf1Ncf1 protein. (391 aa)
ENSXETP00000011099Uncharacterized protein. (197 aa)
ripk1Sequestosome 1. (669 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (594 aa)
dixdc1VRK serine/threonine kinase 1. (693 aa)
rb1cc145 kDa calcium-binding protein. (1576 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (290 aa)
tpm3Tropomyosin 3. (197 aa)
tirapTIR domain-containing protein. (547 aa)
LOC100491693TIR domain-containing protein. (505 aa)
cirbp-2Cold-inducible RNA-binding protein. (933 aa)
sh3rf2Caspase 3, gene 2. (731 aa)
tlr3TIR domain-containing protein; Belongs to the Toll-like receptor family. (917 aa)
ankrd6ANK_REP_REGION domain-containing protein. (776 aa)
wnt11-2Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Shares much functionality with wnt11b. Signals through a non-canonical Wnt pathway to activate Jun-N- terminal kinase (JNK) to regulate gastrulation movements. Acts in a non-cell-autonomous manner to control neural crest migration, probably acting as an extracellular signal from surrounding tissue, but is not required for neural crest induction. Acts redundantly with wnt11b during pronephros induction. Regulates cardiac morphogenesis through the activation of JNK, but is not requ [...] (352 aa)
znf622Basigin (Ok blood group). (466 aa)
ENSXETP00000021784DIX domain-containing protein. (192 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (285 aa)
pycardFamily with sequence similarity 84 member B. (199 aa)
LOC100487218Tripartite motif-containing protein 7-like. (478 aa)
ENSXETP00000000456Uncharacterized protein. (198 aa)
TRAF2TNF receptor-associated factor. (481 aa)
eda2rCarbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7. (294 aa)
appGeneral transcription factor IIE subunit 2. (769 aa)
ska1-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
flt4Transient receptor potential cation channel subfamily M member 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1364 aa)
sh3rf1E3 ubiquitin-protein ligase SH3RF1; Has E3 ubiquitin-protein ligase activity. In the absence of an external substrate, it can catalyze self-ubiquitination. Acts as a scaffold protein that contributes to the effective activation of the JNK signaling pathway; Belongs to the SH3RF family. (873 aa)
TPD52L1TPD52 like 1. (192 aa)
ENSXETP00000033383Protein kinase domain-containing protein. (91 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
traf6TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction. (558 aa)
traf4TNF receptor-associated factor. (470 aa)
gadd45gRibosomal_L7Ae domain-containing protein. (234 aa)
traf1TNF receptor-associated factor. (379 aa)
TNIKTRAF2 and NCK interacting kinase. (1281 aa)
pja2F-box protein 30. (779 aa)
LOC108645626Ran-binding protein 9. (1201 aa)
LOC733866ATP citrate lyase. (390 aa)
ENSXETP00000043337Uncharacterized protein. (185 aa)
naipAsparaginase like 1. (1412 aa)
ENSXETP00000043412NACHT domain-containing protein. (1323 aa)
nrkLIM domain kinase 1. (1177 aa)
mink1NME/NM23 family member 9. (1233 aa)
dusp19Dual specificity phosphatase 19. (215 aa)
map2k4Cytosolic carboxypeptidase 2; Belongs to the protein kinase superfamily. (441 aa)
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa)
mbipUncharacterized protein. (330 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
taok1Exostosin glycosyltransferase 1. (1001 aa)
card9Polymerase (RNA) III (DNA directed) polypeptide G (32kD). (522 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (408 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.