STRINGSTRING
cspg4 cspg4 itgb3 itgb3 ston1 ston1 PDGFD PDGFD plat plat bcar1 bcar1 pdgfrl.2 pdgfrl.2 ptpn1 ptpn1 LOC101732240 LOC101732240 abl2 abl2 LOC100494987 LOC100494987 ABL1 ABL1 pdgfra pdgfra SGPL1 SGPL1 PDGFRB PDGFRB csrnp1 csrnp1 vegfa vegfa pdgfb-2 pdgfb-2 nrp1 nrp1 TXNIP TXNIP zup1-2 zup1-2 zfand5 zfand5 pdgfrl pdgfrl PDGFC PDGFC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cspg4Dual-specificity tyrosine-phosphorylation-regulated kinase 1A. (2183 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (800 aa)
ston1Stonin-1; May be involved in the endocytic machinery. (714 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (389 aa)
platPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
bcar1SH3 domain-containing protein. (951 aa)
pdgfrl.2Ig-like domain-containing protein. (393 aa)
ptpn1Tyrosine-protein phosphatase non-receptor type. (449 aa)
LOC101732240Poly [ADP-ribose] polymerase. (492 aa)
abl2Tyrosine-protein kinase. (1100 aa)
LOC100494987Uncharacterized protein. (485 aa)
ABL1Tyrosine-protein kinase. (1128 aa)
pdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1096 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (573 aa)
PDGFRBPlatelet derived growth factor receptor beta. (1015 aa)
csrnp1AXIN1 up-regulated 1. (574 aa)
vegfaGID complex subunit 8; Belongs to the PDGF/VEGF growth factor family. (311 aa)
pdgfb-2Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (926 aa)
TXNIPThioredoxin interacting protein. (388 aa)
zup1-2Zinc finger containing ubiquitin peptidase 1. (2282 aa)
zfand5High mobility group protein 20A. (211 aa)
pdgfrlPlatelet-derived growth factor receptor-like. (373 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (347 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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