STRINGSTRING
efnb2 efnb2 epha4 epha4 EPHA8 EPHA8 efna2 efna2 epha3 epha3 ENSXETP00000003329 ENSXETP00000003329 LOC108646221 LOC108646221 LOC100494929 LOC100494929 EPHB4 EPHB4 efna1 efna1 ephb1 ephb1 epha7 epha7 crk crk wwc2 wwc2 epha5 epha5 nck2 nck2 EFNB1 EFNB1 pcgf3-2 pcgf3-2 EPHA6 EPHA6 anks1b anks1b dvl2 dvl2 NGEF NGEF sufu-2 sufu-2 nck1 nck1 ephb3 ephb3 efna5 efna5 anks1a anks1a epha10 epha10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
efnb2Solute carrier family 41 member 2; Belongs to the ephrin family. (329 aa)
epha4Uncharacterized protein. (986 aa)
EPHA8EPH receptor A8; Belongs to the protein kinase superfamily. Tyr protein kinase family. (503 aa)
efna2Thyrotrophic embryonic factor; Belongs to the ephrin family. (241 aa)
epha3Transcription factor E2F8. (984 aa)
ENSXETP00000003329SAM domain-containing protein. (158 aa)
LOC108646221Uncharacterized protein. (142 aa)
LOC100494929Aryl hydrocarbon receptor nuclear translocator. (1019 aa)
EPHB4Receptor protein-tyrosine kinase. (739 aa)
efna1Ephrin RBD domain-containing protein; Belongs to the ephrin family. (146 aa)
ephb1Salt inducible kinase 1. (995 aa)
epha7StAR related lipid transfer domain containing 6. (1055 aa)
crkMultivesicular body subunit 12B. (297 aa)
wwc2Protein WWC2; Belongs to the WWC family. (1171 aa)
epha5Poly(A) binding protein, cytoplasmic 1. (947 aa)
nck2Cytoplasmic protein. (381 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (328 aa)
pcgf3-2Polycomb group RING finger protein 3. (130 aa)
EPHA6EPH receptor A6. (1039 aa)
anks1bPID domain-containing protein. (160 aa)
dvl2Segment polarity protein dishevelled homolog DVL-2; Involved in at least 2 independent signaling cascades, controlling cell fate via canonical Wnt signaling and cell polarity via a planar cell polarity (PCP) cascade. Acts synergistically with dal/dapple-like to activate Wnt signaling, stabilizing ctnnb1/beta- catenin and leading to dorsal axis formation. Also prevents degradation of ctnnb1/beta-catenin by displacing gsk3 from a complex with ARP/Axin- related protein. Has an additional role in anterior-posterior (A/P) axis formation, specifying different neuroectodermal cell fates along [...] (316 aa)
NGEFNeuronal guanine nucleotide exchange factor. (691 aa)
sufu-2SUFU negative regulator of hedgehog signaling; Belongs to the ephrin family. (147 aa)
nck1Cytoplasmic protein. (377 aa)
ephb3EPH receptor B3. (988 aa)
efna5Ephrin-A5; Belongs to the ephrin family. (228 aa)
anks1aCytochrome P450 family 1 subfamily A member 1. (1054 aa)
epha10Transcobalamin 2. (365 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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