Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| JUN | esr1 | ENSXETP00000009019 | ENSXETP00000047264 | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.633 |
| JUN | fosl2 | ENSXETP00000009019 | ENSXETP00000002365 | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. | Transmembrane p24 trafficking protein 2. | 0.885 |
| JUN | myc | ENSXETP00000009019 | ENSXETP00000053934 | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. | Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.407 |
| JUN | tp53 | ENSXETP00000009019 | ENSXETP00000041856 | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.546 |
| NF1 | tp53 | ENSXETP00000018932 | ENSXETP00000041856 | Neurofibromin 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.572 |
| PDGFC | pdgfb-2 | ENSXETP00000001334 | ENSXETP00000019350 | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. | Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. | 0.965 |
| abca4-3 | myc | ENSXETP00000028683 | ENSXETP00000053934 | ATP binding cassette subfamily A member 4. | Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.438 |
| bax | tp53 | ENSXETP00000009494 | ENSXETP00000041856 | BCL2-associated X protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.652 |
| cav1 | esr1 | ENSXETP00000048942 | ENSXETP00000047264 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.497 |
| cav1 | itgb3 | ENSXETP00000048942 | ENSXETP00000047166 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Integrin beta; Belongs to the integrin beta chain family. | 0.678 |
| cav3.1 | esr1 | ENSXETP00000046948 | ENSXETP00000047264 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.497 |
| cav3.1 | itgb3 | ENSXETP00000046948 | ENSXETP00000047166 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Integrin beta; Belongs to the integrin beta chain family. | 0.678 |
| cav3.2 | esr1 | ENSXETP00000039803 | ENSXETP00000047264 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.497 |
| cav3.2 | itgb3 | ENSXETP00000039803 | ENSXETP00000047166 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Integrin beta; Belongs to the integrin beta chain family. | 0.678 |
| cdc6 | cdk4 | ENSXETP00000024281 | ENSXETP00000010604 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Coiled-coil domain containing 151; Belongs to the protein kinase superfamily. | 0.743 |
| cdc6 | cdk6 | ENSXETP00000024281 | ENSXETP00000017041 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Epidermal growth factor receptor pathway substrate 15; Belongs to the protein kinase superfamily. | 0.743 |
| cdc6 | e2f1 | ENSXETP00000024281 | ENSXETP00000012293 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | TEA domain family member 1 (SV40 transcriptional enhancer factor). | 0.667 |
| cdk4 | cdc6 | ENSXETP00000010604 | ENSXETP00000024281 | Coiled-coil domain containing 151; Belongs to the protein kinase superfamily. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.743 |
| cdk4 | e2f1 | ENSXETP00000010604 | ENSXETP00000012293 | Coiled-coil domain containing 151; Belongs to the protein kinase superfamily. | TEA domain family member 1 (SV40 transcriptional enhancer factor). | 0.433 |
| cdk4 | tp53 | ENSXETP00000010604 | ENSXETP00000041856 | Coiled-coil domain containing 151; Belongs to the protein kinase superfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.466 |
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