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| | ENOX1 | Ecto-NOX disulfide-thiol exchanger 1. (634 aa) |
| | MC3R | Melanocortin 3 receptor. (317 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa) |
| | atcay-2 | Ataxia, cerebellar, Cayman type. (686 aa) |
| | PSPC1 | Paraspeckle component 1. (517 aa) |
| | kdm2a | Lysine-specific demethylase 2A; Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the c [...] (1146 aa) |
| | ENSXETP00000002697 | JmjN domain-containing protein. (51 aa) |
| | grin3a | Nucleoporin 155kDa; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1124 aa) |
| | kdm5b | Lysosomal-associated membrane protein 2. (1527 aa) |
| | id3 | DNA-binding protein inhibitor ID-3; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Influences cell fate decisions in the embryo by sequestering and blocking the activity of the bHLH transcription factors that control these decisions. Inhibits the binding of myogenic bHLH-containing complexes to E-box DNA, thereby preventing activation of muscle-specific target genes. Also inhibits the activity of neurog [...] (118 aa) |
| | ep300 | Suv3 like RNA helicase. (2493 aa) |
| | cry1 | Forkhead box protein F1. (616 aa) |
| | INHBA | Inhibin subunit beta A. (411 aa) |
| | LOC101733774 | GC-rich promoter binding protein 1-like 1. (170 aa) |
| | kdm5a | Elongator complex protein 1. (1607 aa) |
| | mycbp2 | Vimentin. (4413 aa) |
| | rai1 | Latent transforming growth factor beta binding protein 3. (1847 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (662 aa) |
| | creb1 | DET1, COP1 ubiquitin ligase partner. (341 aa) |
| | HLF | HLF transcription factor, PAR bZIP family member. (296 aa) |
| | rbm4b | NF-kappa-B inhibitor zeta-like. (338 aa) |
| | ezh2 | Histone-lysine N-methyltransferase EZH2; Polycomb group (PcG) protein. Catalytic subunit of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. May regulate the circadian clock via histone methylation at the promoter of the circadian genes; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. EZ subfamily. (763 aa) |
| | mybbp1a | Wolfram syndrome 1 (wolframin). (1233 aa) |
| | mtmr6-2 | Myotubularin related protein 6. (673 aa) |
| | ppp1cb | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity (By similarity). (327 aa) |
| | prok2 | Neurofilament heavy. (209 aa) |
| | homer1 | Prolactin-releasing peptide receptor-like. (394 aa) |
| | gas2 | Forkhead box protein O1. (316 aa) |
| | gga1-2 | Golgi-associated, gamma adaptin ear containing, ARF binding protein 1. (202 aa) |
| | elovl5-2 | Elongation of very long chain fatty acids protein 5. (431 aa) |
| | LOC100158595 | High choriolytic enzyme 2. (427 aa) |
| | bhlhe40-2 | Protein zwilch homolog. (436 aa) |
| | LOC101734139 | HYDIN, axonemal central pair apparatus protein. (467 aa) |
| | kpna6-2 | Transducin beta like 1 X-linked. (394 aa) |
| | tardbp | TAR DNA-binding protein 43; Probably involved in transcriptional repression (By similarity). May play a role in the maintenance of the circadian clock periodicity. (418 aa) |
| | pparg | Peroxisome proliferator activated receptor gamma. (327 aa) |
| | gpr157 | Gpr157 protein. (323 aa) |
| | LOC100486741 | Photolyase/cryptochrome alpha/beta domain-containing protein. (862 aa) |
| | gcm2 | Glial cells missing homolog 2. (288 aa) |
| | btbd9 | ELKS/RAB6-interacting/CAST family member 2. (324 aa) |
| | TNFAIP6 | TNF alpha induced protein 6. (269 aa) |
| | per3 | Integrin linked kinase. (1258 aa) |
| | cipc | LOC100145786 protein. (346 aa) |
| | ntrk1 | Tyrosine-protein kinase receptor. (808 aa) |
| | id2 | DNA-binding protein inhibitor ID-2; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Inhibits the activity of both neurogenic (neurod1/neuroD) and myogenic (myod1/myoD) bHLH factors. May play a role in the regulation of the circadian clock (By similarity). (132 aa) |
| | fbxw7 | Uncharacterized protein. (773 aa) |
| | mttp.1 | Solute carrier family 39 (zinc transporter), member 2. (931 aa) |
| | piwil2 | Piwi-like protein 2; Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. During [...] (949 aa) |
| | KLF10 | Kruppel like factor 10. (465 aa) |
| | opn4 | MCF.2 cell line derived transforming sequence-like. (531 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (192 aa) |
| | ppara | Lysosomal-associated membrane protein 1. (474 aa) |
| | ncoa2 | Nuclear receptor coactivator 2; Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required in a nuclear receptor pathway to suppress expression of dorsal mesoderm genes. May play a role in the positive regulation of the circadian clock. (1509 aa) |
| | ENSXETP00000018238 | Uncharacterized protein. (402 aa) |
| | ENSXETP00000018291 | F-box domain-containing protein. (43 aa) |
| | atf4 | Activating transcription factor 4 (Tax-responsive enhancer element B67). (343 aa) |
| | sirt6 | Sirtuin (Silent mating type information regulation 2 homolog) 6. (331 aa) |
| | cyp1b1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (550 aa) |
| | gpr176 | Small nuclear ribonucleoprotein, U11/U12 25kDa subunit. (581 aa) |
| | LOC101734879 | Uncharacterized protein. (100 aa) |
| | MGC145330 | Protein phosphatase 1 regulatory subunit 12C. (114 aa) |
| | fbxl21p | F-box domain-containing protein. (437 aa) |
| | edn2 | Mesoderm induction early response 1, family member 2. (168 aa) |
| | ENSXETP00000021539 | Uncharacterized protein. (403 aa) |
| | rorc | NR LBD domain-containing protein. (397 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa) |
| | axl | Uncharacterized protein. (914 aa) |
| | AANAT | Aralkylamine N-acetyltransferase. (294 aa) |
| | dnm1l | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa) |
| | sp1 | Nuclear receptor subfamily 2 group E member 3. (747 aa) |
| | cry4 | WD repeat containing, antisense to TP73. (567 aa) |
| | ccdc90b | Coiled-coil domain-containing protein 90B, mitochondrial. (287 aa) |
| | C3orf70 | Chromosome 3 open reading frame 70. (249 aa) |
| | lgr4 | Leucine-rich repeat-containing G-protein coupled receptor 4; Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activat [...] (956 aa) |
| | DRD2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (440 aa) |
| | nr1d1 | Heparan sulfate 6-O-sulfotransferase 3. (529 aa) |
| | FSHB | Follicle stimulating hormone subunit beta. (134 aa) |
| | kdm8 | Lysine-specific demethylase 8; Histone demethylase required for G2/M phase cell cycle progression (By similarity). Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator (By similarity). May play a role in the regulation of the circadian clock (By similarity). (443 aa) |
| | arntl | Sin3A associated protein 18kDa. (513 aa) |
| | ovos2-3 | Alpha-2-macroglobulin like 1 pseudogene. (2368 aa) |
| | thrap3 | Uncharacterized protein. (919 aa) |
| | ncor1 | Nuclear receptor corepressor 1; Mediates transcriptional repression by certain nuclear receptors. Participates in complexes which promote histone deacetylation and the formation of repressive chromatin structures which may impede access by the basal transcription machinery (By similarity). In association with hdac3, may play a role in the regulation of the circadian clock (By similarity). (2407 aa) |
| | enpp2 | Uncharacterized protein. (922 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | dtl | Denticleless protein homolog; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2. CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. [...] (750 aa) |
| | HNF1B | HNF1 homeobox B. (566 aa) |
| | clock | KIAA1324. (850 aa) |
| | ncor2 | EPH receptor A4. (2455 aa) |
| | per2 | Arginase 2. (1410 aa) |
| | bhlhe41 | Uncharacterized protein. (403 aa) |
| | rora | Potassium channel, two pore domain subfamily K, member 4. (518 aa) |
| | nradd | High mobility group box 3. (390 aa) |
| | rarb | Retinoic acid receptor beta. (52 aa) |
| | SETX | Senataxin. (2535 aa) |
| | crtc1 | Josephin domain containing 1. (623 aa) |
| | mapk10 | Mitogen-activated protein kinase. (496 aa) |
| | slit3 | ZXD family zinc finger C. (1519 aa) |
| | gpr149 | WSC domain-containing protein 1. (724 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (573 aa) |
| | fbxw9 | Exocyst complex component 5. (438 aa) |
| | rorb | Radial spoke head protein 9 homolog. (505 aa) |
| | ereg | NIMA-related kinase 6. (156 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (579 aa) |
| | ENSXETP00000032157 | Ion_trans domain-containing protein. (263 aa) |
| | nono | Non-POU domain containing, octamer-binding. (465 aa) |
| | dhx9 | U4/U6 small nuclear ribonucleoprotein Prp31. (1257 aa) |
| | mtor | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2534 aa) |
| | tm4sf4-2 | Transmembrane 4 L six family member 4. (375 aa) |
| | ENSXETP00000033645 | WD_REPEATS_REGION domain-containing protein. (374 aa) |
| | ENSXETP00000033698 | Uncharacterized protein. (613 aa) |
| | ptx3 | Nth-like DNA glycosylase 1. (422 aa) |
| | LOC101734025 | DEAD-box helicase 3 Y-linked. (462 aa) |
| | LOC108644804 | WD_REPEATS_REGION domain-containing protein. (313 aa) |
| | mettl3 | Lysine (K)-specific demethylase 1B; Belongs to the MT-A70-like family. (573 aa) |
| | ddx5 | Uncharacterized protein; Belongs to the DEAD box helicase family. (618 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1129 aa) |
| | ogt | Enolase 4. (1073 aa) |
| | ENSXETP00000034770 | JmjN domain-containing protein. (97 aa) |
| | LOC100144974 | Photolyase/cryptochrome alpha/beta domain-containing protein. (576 aa) |
| | slit2 | ATPase family, AAA domain containing 3A. (1564 aa) |
| | cdk1 | Cell division cycle 2, G1 to S and G2 to M; Belongs to the protein kinase superfamily. (302 aa) |
| | rorb.2 | RNA polymerase-associated protein CTR9 homolog. (475 aa) |
| | dbp | Methyl-CpG binding domain protein 2. (311 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (692 aa) |
| | lhcgr | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (708 aa) |
| | noct | CCR4 carbon catabolite repression 4-like (S. cerevisiae). (458 aa) |
| | nfya | Uncharacterized protein. (326 aa) |
| | prkaa1 | Non-specific serine/threonine protein kinase. (571 aa) |
| | hdac3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (By similarity). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May play a role in the regulation of the circadian clock in a deacetylase activity-independent manner (By similarity). (449 aa) |
| | nfil3 | Nuclear factor interleukin-3-regulated protein; May act as a transcriptional regulator of a number of proteins of the circadian clock. (462 aa) |
| | LOC100485437 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (536 aa) |
| | ADNP | Activity dependent neuroprotector homeobox. (1093 aa) |
| | egr3 | Serpin peptidase inhibitor, clade B (ovalbumin), member 4. (376 aa) |
| | nudt12 | Paired like homeobox 2B. (458 aa) |
| | ppargc1a | LETM1 domain-containing protein LETM2, mitochondrial. (810 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (782 aa) |
| | ptn | Glycine receptor alpha 3. (190 aa) |
| | tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa) |
| | top1.2 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (775 aa) |
| | LOC105945772 | ARID domain-containing protein. (170 aa) |
| | csnk1e | DEAD-box helicase 24. (516 aa) |
| | thibz | Choroideremia (Rab escort protein 1). (335 aa) |
| | LOC100486093 | Ro60, Y RNA binding protein. (346 aa) |
| | cartpt | Uncharacterized protein. (113 aa) |
| | mapk8 | Mitogen-activated protein kinase. (541 aa) |
| | ciart | A-kinase anchoring protein 2. (436 aa) |
| | pam | Uncharacterized protein. (985 aa) |
| | kiaa2013 | Uncharacterized protein KIAA2013 homolog. (614 aa) |
| | stk11ip | Serine/threonine-protein kinase 11-interacting protein. (1160 aa) |
| | per1 | PAS domain-containing protein. (914 aa) |
| | atf5.2 | Tubulin tyrosine ligase like11. (311 aa) |
| | atf5 | BZIP domain-containing protein. (311 aa) |
| | cry-dash | Family with sequence similarity 92 member B. (445 aa) |
| | nrip1 | Rho guanine nucleotide exchange factor 12. (1138 aa) |
| | SCAPER | S-phase cyclin A associated protein in the ER. (1427 aa) |
| | rack1 | Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1. (317 aa) |
| | DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (414 aa) |
| | bhlhe40 | ADAMTS like 4. (226 aa) |
| | nampt | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (506 aa) |
| | exd2-2 | Exonuclease 3'-5' domain containing 2; Belongs to the G-protein coupled receptor 1 family. (440 aa) |
| | uxs1-2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (209 aa) |
| | ahr | Uncharacterized protein. (843 aa) |
| | esr1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa) |
| | ntrk2 | Tyrosine-protein kinase receptor. (821 aa) |
| | ndufa9 | Tetratricopeptide repeat domain 27. (380 aa) |
| | rock2 | Mediator of RNA polymerase II transcription subunit 18; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1461 aa) |
| | sfpq | Peptidyl-tRNA hydrolase domain containing 1. (665 aa) |
| | prkaa2 | Non-specific serine/threonine protein kinase. (564 aa) |
| | egr1 | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...] (498 aa) |
| | sirt1 | Thrombospondin-type laminin G domain and EAR repeats. (707 aa) |
| | id4 | DNA-binding protein inhibitor ID-4; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Inhibits the activity of both neurogenic (neurog1/neurogenin, neurod1/neuroD) and myogenic (myod1/myoD) bHLH factors (By similarity). (131 aa) |
| | NGFR | Nerve growth factor receptor. (398 aa) |
| | atoh7 | Peptidylprolyl isomerase like 6. (139 aa) |
| | fbxo32-2 | Sorting nexin-31. (489 aa) |
| | cyp1c1 | Smad nuclear interacting protein 1; Belongs to the cytochrome P450 family. (524 aa) |
| | timeless | Heat shock protein family H (Hsp110) member 1. (1287 aa) |
