STRINGSTRING
sec24b sec24b DLL4 DLL4 NOTCH3 NOTCH3 BMPR2 BMPR2 myocd myocd ednra ednra angptl3 angptl3 tgfbr1 tgfbr1 hand2 hand2 hpgd hpgd STRA6 STRA6 srf srf jag1 jag1 prdm1 prdm1 gja5 gja5 nprl3 nprl3 SMAD7 SMAD7 ARID2 ARID2 edn1 edn1 pkd2 pkd2 acvrl1 acvrl1 eng eng gucy2f-2 gucy2f-2 ENSXETP00000018846 ENSXETP00000018846 NF1 NF1 adgrf1 adgrf1 fgf8 fgf8 fkbp10 fkbp10 apob apob
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sec24bCaM kinase-like vesicle-associated. (1103 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (679 aa)
NOTCH3Notch receptor 3. (2413 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1053 aa)
myocdYip1 domain family member 1. (956 aa)
ednraEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (414 aa)
angptl3Carboxylesterase 3, gene 1. (456 aa)
tgfbr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
hand2Hand2 protein. (210 aa)
hpgdArmadillo repeat containing 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
STRA6Stimulated by retinoic acid 6. (637 aa)
srfHydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7. (359 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
prdm1ChaC, cation transport regulator homolog 2. (784 aa)
gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (364 aa)
nprl3Insulin-like growth factor-binding protein complex acid labile subunit-like. (580 aa)
SMAD7Mothers against decapentaplegic homolog. (382 aa)
ARID2AT-rich interaction domain 2. (1816 aa)
edn1Nidogen 2. (222 aa)
pkd2Ubiquitin carboxyl-terminal hydrolase 33. (951 aa)
acvrl1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (490 aa)
engUncharacterized protein. (622 aa)
gucy2f-2Guanylate cyclase 2F, retinal; Belongs to the G-protein coupled receptor 2 family. (515 aa)
ENSXETP00000018846Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (441 aa)
NF1Neurofibromin 1. (2812 aa)
adgrf1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1; Belongs to the G-protein coupled receptor 2 family. (1231 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
fkbp10Peptidylprolyl isomerase. (580 aa)
apobProbable ATP-dependent RNA helicase ddx6. (4594 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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