(62 nodes) Regulation of viral process network (Xenopus tropicalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tnf	Thyrotropin-releasing hormone receptor 3. (227 aa)
	ppid	Proline-rich nuclear receptor coactivator 2. (370 aa)
	TOP2A	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1698 aa)
	ADAR	Adenosine deaminase RNA specific. (1119 aa)
	stac	SH3 and cysteine rich domain. (220 aa)
	pkr3	Uncharacterized protein. (473 aa)
	ENSXETP00000003801	Putative transmembrane protein TA-2. (399 aa)
	tmprss4	FKBP prolyl isomerase 14; Belongs to the peptidase S1 family. (808 aa)
	stau1	Uncharacterized protein. (721 aa)
	baf-l	Uncharacterized protein. (91 aa)
	LOC100498389	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (97 aa)
	banf1	Prostaglandin E receptor 3. (84 aa)
	lgals1.3	Galectin. (135 aa)
	lgals1.1	Galectin. (134 aa)
	tmem250	Uncharacterized protein. (139 aa)
	TRIM14	Tripartite motif containing 14. (429 aa)
	LOC100491070	Uncharacterized protein. (469 aa)
	cd74	Synovial sarcoma translocation gene on chromosome 18-like 1. (291 aa)
	rsad2	Proteasome subunit alpha 2. (393 aa)
	ppara	Lysosomal-associated membrane protein 1. (474 aa)
	rsf1	Sterol O-acyltransferase 2. (1424 aa)
	setdb1	Uncharacterized protein. (1284 aa)
	tbc1d20.1	Rab-GAP TBC domain-containing protein. (382 aa)
	axl	Uncharacterized protein. (914 aa)
	znfx1	Osteoclast stimulating factor 1. (1889 aa)
	vps37b	Vacuolar protein sorting 37 homolog B. (287 aa)
	ifnl2	Type III interferon 5. (179 aa)
	tarbp2	RISC-loading complex subunit tarbp2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Within the RLC/miRLC, dicer1 and tarbp2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto ago2. ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from dicer1 and tarbp2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (386 aa)
	trim8	Fin bud initiation factor homolog. (551 aa)
	eif2ak2	Retinol dehydrogenase 7, gene 2. (557 aa)
	tsg101	Thrombospondin 2. (239 aa)
	apcs.2	Pentaxin. (230 aa)
	crp.4	Pentaxin. (238 aa)
	MGC107876	Pentaxin. (237 aa)
	apcs	Pentaxin. (237 aa)
	n4bp1	NEDD4-binding protein 1; Inhibitor of the E3 ubiquitin-protein ligase itch. Belongs to the N4BP1 family. (819 aa)
	fkbp6	Peptidylprolyl isomerase. (323 aa)
	atg12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (133 aa)
	BCL2	BCL2 apoptosis regulator. (293 aa)
	dhx9	U4/U6 small nuclear ribonucleoprotein Prp31. (1257 aa)
	tasor	Urotensin-2 receptor-like. (1565 aa)
	cradd.2-2	Phospholipase A2 group III. (137 aa)
	ptx3	Nth-like DNA glycosylase 1. (422 aa)
	LOC101734947	Chemokine (C-X-C motif) receptor 6. (94 aa)
	tert-2	Myotubularin related protein 12. (243 aa)
	morc2	CW-type domain-containing protein. (1026 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	parp10	Poly [ADP-ribose] polymerase. (621 aa)
	DDB1	Damage specific DNA binding protein 1. (1129 aa)
	hmga2	Rho guanine nucleotide exchange factor 38. (150 aa)
	lgals1.4	Galectin. (126 aa)
	lgals1.2	Galectin. (135 aa)
	trim32	LOC100124994 protein. (649 aa)
	inpp5k	IPPc domain-containing protein. (547 aa)
	PPIE	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (319 aa)
	ENSXETP00000047005	Uncharacterized protein. (222 aa)
	larp1	HTH La-type RNA-binding domain-containing protein. (1022 aa)
	TOP2B	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1748 aa)
	PDE12	Phosphodiesterase 12. (537 aa)
	IFIH1	Interferon induced with helicase C domain 1. (992 aa)
	ENSXETP00000053506	NACHT domain-containing protein. (837 aa)
	tmem39b	Transmembrane protein 39B. (483 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAR	ENSXETP00000003801	ENSXETP00000003234	ENSXETP00000003801	Adenosine deaminase RNA specific.	Putative transmembrane protein TA-2.	0.480
ADAR	IFIH1	ENSXETP00000003234	ENSXETP00000053027	Adenosine deaminase RNA specific.	Interferon induced with helicase C domain 1.	0.558
ADAR	dhx9	ENSXETP00000003234	ENSXETP00000032394	Adenosine deaminase RNA specific.	U4/U6 small nuclear ribonucleoprotein Prp31.	0.619
ADAR	eif2ak2	ENSXETP00000003234	ENSXETP00000024460	Adenosine deaminase RNA specific.	Retinol dehydrogenase 7, gene 2.	0.480
ADAR	pkr3	ENSXETP00000003234	ENSXETP00000003791	Adenosine deaminase RNA specific.	Uncharacterized protein.	0.480
ADAR	znfx1	ENSXETP00000003234	ENSXETP00000022816	Adenosine deaminase RNA specific.	Osteoclast stimulating factor 1.	0.588
BCL2	LOC100491070	ENSXETP00000032076	ENSXETP00000017485	BCL2 apoptosis regulator.	Uncharacterized protein.	0.709
BCL2	atg12	ENSXETP00000032076	ENSXETP00000031722	BCL2 apoptosis regulator.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.708
BCL2	atg5	ENSXETP00000032076	ENSXETP00000034480	BCL2 apoptosis regulator.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.593
DDB1	LOC100491070	ENSXETP00000034669	ENSXETP00000017485	Damage specific DNA binding protein 1.	Uncharacterized protein.	0.459
ENSXETP00000003801	ADAR	ENSXETP00000003801	ENSXETP00000003234	Putative transmembrane protein TA-2.	Adenosine deaminase RNA specific.	0.480
ENSXETP00000003801	IFIH1	ENSXETP00000003801	ENSXETP00000053027	Putative transmembrane protein TA-2.	Interferon induced with helicase C domain 1.	0.633
ENSXETP00000003801	rsad2	ENSXETP00000003801	ENSXETP00000017966	Putative transmembrane protein TA-2.	Proteasome subunit alpha 2.	0.685
ENSXETP00000047005	LOC100491070	ENSXETP00000047005	ENSXETP00000017485	Uncharacterized protein.	Uncharacterized protein.	0.681
ENSXETP00000053506	LOC100491070	ENSXETP00000053506	ENSXETP00000017485	NACHT domain-containing protein.	Uncharacterized protein.	0.666
ENSXETP00000053506	cd74	ENSXETP00000053506	ENSXETP00000017886	NACHT domain-containing protein.	Synovial sarcoma translocation gene on chromosome 18-like 1.	0.583
IFIH1	ADAR	ENSXETP00000053027	ENSXETP00000003234	Interferon induced with helicase C domain 1.	Adenosine deaminase RNA specific.	0.558
IFIH1	ENSXETP00000003801	ENSXETP00000053027	ENSXETP00000003801	Interferon induced with helicase C domain 1.	Putative transmembrane protein TA-2.	0.633
IFIH1	atg12	ENSXETP00000053027	ENSXETP00000031722	Interferon induced with helicase C domain 1.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.686
IFIH1	atg5	ENSXETP00000053027	ENSXETP00000034480	Interferon induced with helicase C domain 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.638

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