STRINGSTRING
RIPK2 RIPK2 polr3c polr3c cacnb4 cacnb4 hhla2 hhla2 FOXP3 FOXP3 spg21 spg21 ppdpf ppdpf myzap myzap tnfrsf21 tnfrsf21 ptpn6 ptpn6 stoml2 stoml2 psen1 psen1 THY1 THY1 nfatc2 nfatc2 btk btk cd79a cd79a bax bax kctd1 kctd1 bcl10 bcl10 itk itk rbck1 rbck1 phc3-2 phc3-2 eif2b1 eif2b1 acly-2 acly-2 plcxd3 plcxd3 ENSXETP00000004850 ENSXETP00000004850 ENSXETP00000004837 ENSXETP00000004837 hsd17b2 hsd17b2 phactr1-2 phactr1-2 nfkbiz nfkbiz itih5-2 itih5-2 blk blk MALT1 MALT1 eif2b5 eif2b5 stk11 stk11 eif2b2 eif2b2 cd28 cd28 wdr1 wdr1 snrpb2-3 snrpb2-3 ebna1bp2-4 ebna1bp2-4 dennd1b dennd1b eif2b3 eif2b3 klhl6 klhl6 top1mt top1mt BRAF BRAF BCL2 BCL2 cd247 cd247 prkcb prkcb tubg1 tubg1 zap70 zap70 rnf31 rnf31 syk syk sppl3 sppl3 asxl3-2 asxl3-2 LOC100489320 LOC100489320 LOC100489483 LOC100489483 vtcn1 vtcn1 ano3 ano3 lyn lyn TEC TEC eif3l eif3l PLCG1 PLCG1 bcar1 bcar1 PLCG2 PLCG2 gata3 gata3 pcasp3 pcasp3 RC3H1 RC3H1 morn5 morn5 rftn1 rftn1 smarcal1 smarcal1 idi1-2 idi1-2 Zc3h12a Zc3h12a gm2a-2 gm2a-2 CD276 CD276 khdrbs1 khdrbs1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIPK2Receptor interacting serine/threonine kinase 2. (408 aa)
polr3cNucleoside diphosphate-linked moiety X motif 17; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. (568 aa)
cacnb4SH3 domain-containing protein. (550 aa)
hhla2Uncharacterized protein. (377 aa)
FOXP3Forkhead box P3. (412 aa)
spg21Serum/glucocorticoid-regulated kinase 2. (314 aa)
ppdpfPancreatic progenitor cell differentiation and proliferation factor; Probable regulator of exocrine pancreas development. (77 aa)
myzapMyocardial zonula adherens protein; Belongs to the MYZAP family. (519 aa)
tnfrsf21Uncharacterized protein. (615 aa)
ptpn6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (601 aa)
stoml2PHB domain-containing protein. (341 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa)
THY1Thy-1 cell surface antigen. (136 aa)
nfatc2ADP-ribosylation factor-like protein 8A. (900 aa)
btkTyrosine-protein kinase. (649 aa)
cd79aUrocanate hydratase 1. (239 aa)
baxBCL2-associated X protein. (221 aa)
kctd1Potassium channel tetramerization domain containing 1. (302 aa)
bcl10Solute carrier family 35 (GDP-fucose transporter), member C2. (236 aa)
itkSR-related CTD associated factor 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. (562 aa)
rbck1RING-type domain-containing protein. (282 aa)
phc3-2Polyhomeotic homolog 3. (298 aa)
eif2b1Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (345 aa)
acly-2Pituitary tumor-transforming 1 interacting protein, gene 2. (517 aa)
plcxd3Phosphatidylinositol-specific phospholipase C, X domain containing 3. (141 aa)
ENSXETP00000004850Ig-like domain-containing protein. (124 aa)
ENSXETP00000004837Ig-like domain-containing protein. (124 aa)
hsd17b2Hydroxysteroid (17-beta) dehydrogenase 2. (120 aa)
phactr1-2Ig-like domain-containing protein. (123 aa)
nfkbizLeucine rich repeat containing 75B. (652 aa)
itih5-2Leucine rich repeat containing 41. (180 aa)
blkTyrosine-protein kinase. (497 aa)
MALT1MALT1 paracaspase. (799 aa)
eif2b5Thymosin beta 4 X-linked. (730 aa)
stk11Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (442 aa)
eif2b2Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
cd28Cd28 protein. (210 aa)
wdr1WD repeat-containing protein 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Doesn't sever actin filaments alone, but caps the barbed ends of filaments severed by cofilin, which blocks annealing and depolymerization and allows more extensive severing by cofilin (By similarity); Belongs to the WD repeat AIP1 family. (609 aa)
snrpb2-3Small nuclear ribonucleoprotein polypeptide B. (115 aa)
ebna1bp2-4EBNA1 binding protein 2. (876 aa)
dennd1bPoliovirus receptor-related 3. (593 aa)
eif2b3NTP_transferase domain-containing protein. (460 aa)
klhl6Estrogen receptor 2. (610 aa)
top1mtPhosphoinositide phospholipase C. (1368 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (908 aa)
BCL2BCL2 apoptosis regulator. (293 aa)
cd247Voltage-dependent anion channel 3. (160 aa)
prkcbProtein kinase C beta type; Calcium-activated and phospholipid-dependent serine/threonine-protein kinase involved in various processes such as regulation of the B-cell receptor (BCR) signalosome, apoptosis and transcription regulation. Plays a key role in B-cell activation and function by regulating BCR-induced NF-kappa-B activation and B-cell survival. Required for recruitment and activation of the IKK kinase to lipid rafts and mediates phosphorylation of card11/carma1, leading to activate the NF-kappa-B signaling. Involved in apoptosis following oxidative damage: in case of oxidative [...] (671 aa)
tubg1Tubulin gamma 1. (758 aa)
zap70Tyrosine-protein kinase. (609 aa)
rnf31Uncharacterized protein. (1034 aa)
sykTyrosine-protein kinase. (611 aa)
sppl3Signal peptide peptidase 3. (410 aa)
asxl3-2ASXL transcriptional regulator 3. (584 aa)
LOC100489320Cell division cycle 16. (231 aa)
LOC100489483Ig-like domain-containing protein. (262 aa)
vtcn1Glutamate receptor, ionotropic, kainate 4. (254 aa)
ano3Anoctamin 3. (249 aa)
lynTyrosine-protein kinase. (524 aa)
TECTyrosine-protein kinase. (641 aa)
eif3lEukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (593 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1269 aa)
bcar1SH3 domain-containing protein. (951 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1256 aa)
gata3Uncharacterized protein. (454 aa)
pcasp3Uncharacterized protein. (632 aa)
RC3H1Ring finger and CCCH-type domains 1. (1123 aa)
morn5MORN repeat-containing protein 5. (178 aa)
rftn1LOC100127747 protein. (611 aa)
smarcal1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA (By similarity); Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (941 aa)
idi1-2Isopentenyl-diphosphate delta isomerase 1. (290 aa)
Zc3h12aC3H1-type domain-containing protein. (349 aa)
gm2a-2GM2 ganglioside activator. (587 aa)
CD276CD276 molecule. (332 aa)
khdrbs1Phosducin. (377 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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