(17 nodes) Positive chemotaxis network (Xenopus tropicalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	met	UTP6 small subunit processome component. (1402 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	lgals3	Galectin. (256 aa)
	VEGFD	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (333 aa)
	VEGFC	Vascular endothelial growth factor C. (407 aa)
	scg2	BRX1, biogenesis of ribosomes. (624 aa)
	tsc2	Mannosidase, alpha, class 1B, member 1. (1798 aa)
	pdgfb-2	Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
	SCRIB	Scribble planar cell polarity protein. (945 aa)
	vegfa	GID complex subunit 8; Belongs to the PDGF/VEGF growth factor family. (311 aa)
	colec10	Collectin-10; Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine; Belongs to the COLEC10/COLEC11 family. (275 aa)
	vegfb	Bradykinin receptor B2. (251 aa)
	alkbh1	Solute carrier family 35 member D3. (398 aa)
	lrrc1	Uncharacterized protein. (508 aa)
	cxcl11	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	cxcl9	Cyclin-dependent kinase 2 associated protein 2. (96 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HGF	VEGFC	ENSXETP00000052984	ENSXETP00000013902	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Vascular endothelial growth factor C.	0.935
HGF	VEGFD	ENSXETP00000052984	ENSXETP00000011563	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	0.917
HGF	fgf7	ENSXETP00000052984	ENSXETP00000054080	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.679
HGF	met	ENSXETP00000052984	ENSXETP00000049079	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	UTP6 small subunit processome component.	0.990
HGF	pdgfb-2	ENSXETP00000052984	ENSXETP00000019350	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Frizzled related protein; Belongs to the PDGF/VEGF growth factor family.	0.914
HGF	vegfa	ENSXETP00000052984	ENSXETP00000021996	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	GID complex subunit 8; Belongs to the PDGF/VEGF growth factor family.	0.900
VEGFC	HGF	ENSXETP00000013902	ENSXETP00000052984	Vascular endothelial growth factor C.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.935
VEGFC	VEGFD	ENSXETP00000013902	ENSXETP00000011563	Vascular endothelial growth factor C.	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	0.919
VEGFC	met	ENSXETP00000013902	ENSXETP00000049079	Vascular endothelial growth factor C.	UTP6 small subunit processome component.	0.700
VEGFC	pdgfb-2	ENSXETP00000013902	ENSXETP00000019350	Vascular endothelial growth factor C.	Frizzled related protein; Belongs to the PDGF/VEGF growth factor family.	0.931
VEGFC	vegfa	ENSXETP00000013902	ENSXETP00000021996	Vascular endothelial growth factor C.	GID complex subunit 8; Belongs to the PDGF/VEGF growth factor family.	0.900
VEGFC	vegfb	ENSXETP00000013902	ENSXETP00000035774	Vascular endothelial growth factor C.	Bradykinin receptor B2.	0.576
VEGFD	HGF	ENSXETP00000011563	ENSXETP00000052984	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.917
VEGFD	VEGFC	ENSXETP00000011563	ENSXETP00000013902	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor C.	0.919
VEGFD	met	ENSXETP00000011563	ENSXETP00000049079	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	UTP6 small subunit processome component.	0.681
VEGFD	pdgfb-2	ENSXETP00000011563	ENSXETP00000019350	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	Frizzled related protein; Belongs to the PDGF/VEGF growth factor family.	0.908
VEGFD	vegfa	ENSXETP00000011563	ENSXETP00000021996	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	GID complex subunit 8; Belongs to the PDGF/VEGF growth factor family.	0.900
cxcl11	cxcl9	ENSXETP00000044924	ENSXETP00000044932	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.	Cyclin-dependent kinase 2 associated protein 2.	0.912
cxcl9	cxcl11	ENSXETP00000044932	ENSXETP00000044924	Cyclin-dependent kinase 2 associated protein 2.	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.	0.912
fgf7	HGF	ENSXETP00000054080	ENSXETP00000052984	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.679

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