STRINGSTRING
dynlt1 dynlt1 spry1 spry1 fam193a fam193a mapre1 mapre1 sapcd1 sapcd1 gpsm2 gpsm2 misp3 misp3 zw10 zw10 LLGL1 LLGL1 ndel1 ndel1 LOC108648944 LOC108648944 INSC INSC htt htt LOC100485335 LOC100485335 spag5 spag5 Rskr Rskr misp misp pafah1b1 pafah1b1 LOC100490407 LOC100490407 MOS MOS UBXN2B UBXN2B mcph1 mcph1 gje1 gje1 llgl2 llgl2 gpsm1 gpsm1 nde1 nde1 Map4 Map4 numa1 numa1 PKHD1 PKHD1 dctn1 dctn1 pax6 pax6 mad2l1 mad2l1 spdl1 spdl1 fam193b fam193b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dynlt1Transcription factor 7. (145 aa)
spry1Mitochondrial amidoxime reducing component 1. (342 aa)
fam193aChromosome 1 open reading frame 43. (1570 aa)
mapre1Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Belongs to the MAPRE family. (302 aa)
sapcd1Uncharacterized protein. (299 aa)
gpsm2Ribonucleotide reductase M1. (663 aa)
misp3Uncharacterized protein. (788 aa)
zw10Uncharacterized protein. (780 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1052 aa)
ndel1Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. (345 aa)
LOC108648944Uncharacterized protein. (401 aa)
INSCINSC spindle orientation adaptor protein. (418 aa)
httDihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). (3110 aa)
LOC100485335Poly(A) polymerase alpha. (281 aa)
spag5Interferon induced, with helicase C domain 1. (1498 aa)
RskrProtein kinase domain-containing protein. (180 aa)
mispAKAP2_C domain-containing protein. (817 aa)
pafah1b1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (414 aa)
LOC100490407Ribonucleoprotein, PTB binding 2. (1408 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (355 aa)
UBXN2BUBX domain protein 2B. (351 aa)
mcph1Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa. (820 aa)
gje1Gap junction protein epsilon 1. (132 aa)
llgl2Lethal giant larvae homolog 2. (1019 aa)
gpsm1Uncharacterized protein. (625 aa)
nde1Nuclear distribution protein nudE homolog 1; Required for centrosome duplication and formation and function of the mitotic spindle; Belongs to the nudE family. (340 aa)
Map4Microtubule-associated protein. (2108 aa)
numa1Kynurenine aminotransferase 3. (2351 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (3166 aa)
dctn1CAP-Gly domain-containing protein. (1290 aa)
pax6Uncharacterized protein. (456 aa)
mad2l1PIF1 5'-to-3' DNA helicase. (203 aa)
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. May act as an adapter protein linking the dynein motor complex to various cargos (By similarity); Belongs to the Spindly family. (611 aa)
fam193bCyclin-Y-like protein 1. (632 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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