(45 nodes) Modulation by host of symbiont process network (Xenopus tropicalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ep300	Suv3 like RNA helicase. (2493 aa)
	ythdc2	Serine/threonine-protein kinase Sgk1. (1419 aa)
	ppib	Antizyme inhibitor 1. (301 aa)
	csf1r	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (935 aa)
	tfap4	RNA binding motif protein 28. (333 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (312 aa)
	lef1	HMG box domain-containing protein. (415 aa)
	SAP30BP	SAP30 binding protein. (301 aa)
	pou2f3	POU domain protein. (207 aa)
	pi4ka	Cordon-bleu WH2 repeat protein; Belongs to the PI3/PI4-kinase family. (2088 aa)
	CHD1	Chromodomain helicase DNA binding protein 1. (1748 aa)
	pc.2	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1214 aa)
	tbc1d20.1	Rab-GAP TBC domain-containing protein. (382 aa)
	ST6GALNAC1	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (445 aa)
	sp1	Nuclear receptor subfamily 2 group E member 3. (747 aa)
	rrp1b	Sarcoglycan alpha. (606 aa)
	apcs.2	Pentaxin. (230 aa)
	CCNT1	CYCLIN domain-containing protein; Belongs to the cyclin family. (631 aa)
	crp.4	Pentaxin. (238 aa)
	MGC107876	Pentaxin. (237 aa)
	apcs	Pentaxin. (237 aa)
	rab29	LOC100135159 protein. (204 aa)
	nucks1	Nuclear casein kinase and cyclin-dependent kinase substrate 1. (291 aa)
	jund.2	mRNA export factor. (448 aa)
	ptx3	Nth-like DNA glycosylase 1. (422 aa)
	hmga2	Rho guanine nucleotide exchange factor 38. (150 aa)
	hpn	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (417 aa)
	lrrc19	Sphingomyelin synthase 2. (364 aa)
	snw1	Kelch repeat and BTB domain-containing protein 8. (549 aa)
	inpp5k	IPPc domain-containing protein. (547 aa)
	IGF2R	Insulin like growth factor 2 receptor. (2400 aa)
	psmc3	CD248 molecule; Belongs to the AAA ATPase family. (440 aa)
	znf639	Histone-lysine N-methyltransferase EZH2. (430 aa)
	REST	RE1 silencing transcription factor. (1442 aa)
	ctdp1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (994 aa)
	eea1	Ovo like zinc finger 1. (1412 aa)
	rock2	Mediator of RNA polymerase II transcription subunit 18; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1461 aa)
	cav2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (160 aa)
	eif2ak4	Uncharacterized protein. (1668 aa)
	ccnk	Uncharacterized protein; Belongs to the cyclin family. (659 aa)
	phb	Prohibitin. (272 aa)
	NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D. (440 aa)
	idi1-2	Isopentenyl-diphosphate delta isomerase 1. (290 aa)
	Zc3h12a	C3H1-type domain-containing protein. (349 aa)
	card9	Polymerase (RNA) III (DNA directed) polypeptide G (32kD). (522 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNT1	ccnk	ENSXETP00000028520	ENSXETP00000049621	CYCLIN domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.441
JUN	ep300	ENSXETP00000009019	ENSXETP00000003819	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Suv3 like RNA helicase.	0.781
JUN	sp1	ENSXETP00000009019	ENSXETP00000023264	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Nuclear receptor subfamily 2 group E member 3.	0.628
Zc3h12a	idi1-2	ENSXETP00000052384	ENSXETP00000052378	C3H1-type domain-containing protein.	Isopentenyl-diphosphate delta isomerase 1.	0.907
ccnk	CCNT1	ENSXETP00000049621	ENSXETP00000028520	Uncharacterized protein; Belongs to the cyclin family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.441
ccnk	ctdp1	ENSXETP00000049621	ENSXETP00000047262	Uncharacterized protein; Belongs to the cyclin family.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.573
ctdp1	ccnk	ENSXETP00000047262	ENSXETP00000049621	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Uncharacterized protein; Belongs to the cyclin family.	0.573
ep300	JUN	ENSXETP00000003819	ENSXETP00000009019	Suv3 like RNA helicase.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.781
ep300	jund.2	ENSXETP00000003819	ENSXETP00000032034	Suv3 like RNA helicase.	mRNA export factor.	0.781
ep300	lef1	ENSXETP00000003819	ENSXETP00000010536	Suv3 like RNA helicase.	HMG box domain-containing protein.	0.943
ep300	sp1	ENSXETP00000003819	ENSXETP00000023264	Suv3 like RNA helicase.	Nuclear receptor subfamily 2 group E member 3.	0.985
idi1-2	Zc3h12a	ENSXETP00000052378	ENSXETP00000052384	Isopentenyl-diphosphate delta isomerase 1.	C3H1-type domain-containing protein.	0.907
jund.2	ep300	ENSXETP00000032034	ENSXETP00000003819	mRNA export factor.	Suv3 like RNA helicase.	0.781
jund.2	sp1	ENSXETP00000032034	ENSXETP00000023264	mRNA export factor.	Nuclear receptor subfamily 2 group E member 3.	0.628
lef1	ep300	ENSXETP00000010536	ENSXETP00000003819	HMG box domain-containing protein.	Suv3 like RNA helicase.	0.943
nucks1	rab29	ENSXETP00000028991	ENSXETP00000028964	Nuclear casein kinase and cyclin-dependent kinase substrate 1.	LOC100135159 protein.	0.622
ppib	snw1	ENSXETP00000004234	ENSXETP00000040699	Antizyme inhibitor 1.	Kelch repeat and BTB domain-containing protein 8.	0.439
rab29	nucks1	ENSXETP00000028964	ENSXETP00000028991	LOC100135159 protein.	Nuclear casein kinase and cyclin-dependent kinase substrate 1.	0.622
snw1	ppib	ENSXETP00000040699	ENSXETP00000004234	Kelch repeat and BTB domain-containing protein 8.	Antizyme inhibitor 1.	0.439
snw1	ythdc2	ENSXETP00000040699	ENSXETP00000000399	Kelch repeat and BTB domain-containing protein 8.	Serine/threonine-protein kinase Sgk1.	0.505

page 1 of 2

Server load: low (28%) [HD]

Permalink

Network

Fusion

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Neighborhood

© STRING Consortium 2025

Credits

Access

Info

About