STRINGSTRING
tgfb1 tgfb1 med1l med1l zfpm2 zfpm2 Tnni1 Tnni1 eng eng smad4.1 smad4.1 nkx2-5 nkx2-5 tgfbr1 tgfbr1 tnnc1 tnnc1 ptcd2 ptcd2 ednra ednra hand1 hand1 DLL4 DLL4 tnni3 tnni3 SMAD7 SMAD7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
med1lMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (678 aa)
zfpm2GPI mannosyltransferase 1. (1151 aa)
Tnni1Uncharacterized protein. (152 aa)
engUncharacterized protein. (622 aa)
smad4.1Mothers against decapentaplegic homolog. (579 aa)
nkx2-5Toll-like receptor12. (300 aa)
tgfbr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
tnnc1CTD small phosphatase like. (161 aa)
ptcd2Uncharacterized protein. (382 aa)
ednraEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (414 aa)
hand1Glycogen synthase kinase 3 beta. (213 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (679 aa)
tnni3Transmembrane protein 256. (245 aa)
SMAD7Mothers against decapentaplegic homolog. (382 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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