STRINGSTRING
TSPAN12 TSPAN12 alcam alcam FAT3 FAT3 nrl nrl RPGRIP1L RPGRIP1L vsx1 vsx1 rpgrip1 rpgrip1 mtmr6-2 mtmr6-2 VAX1 VAX1 tor3a-2 tor3a-2 THY1 THY1 irx1 irx1 lrp5 lrp5 cabp4 cabp4 SOX8 SOX8 dlc dlc AHI1 AHI1 TTC8 TTC8 MEGF11 MEGF11 crb1 crb1 dll1 dll1 rorb rorb crb2 crb2 foxn4 foxn4 foxc1 foxc1 fjx1 fjx1 Rp1 Rp1 pde6c pde6c ntrk2 ntrk2 hao2-2 hao2-2 PTF1A PTF1A calb1 calb1 sox11 sox11 SDK2 SDK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TSPAN12Tetraspanin. (304 aa)
alcamUncharacterized protein. (573 aa)
FAT3FAT atypical cadherin 3. (4579 aa)
nrlGolgi brefeldin A resistant guanine nucleotide exchange factor 1. (289 aa)
RPGRIP1LRPGRIP1 like. (1266 aa)
vsx1Semaphorin 3F like. (344 aa)
rpgrip1Myelin regulatory factor. (1279 aa)
mtmr6-2Myotubularin related protein 6. (673 aa)
VAX1Ventral anterior homeobox 1. (149 aa)
tor3a-2Torsin family 3, member A. (249 aa)
THY1Thy-1 cell surface antigen. (136 aa)
irx1Iroquois-class homeodomain protein irx-1; Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state. Also up- regulates repressors that prevent neuronal differentiation. Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes. Acts primarily as a transcriptional repressor during neural development, and binds [...] (467 aa)
lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
cabp4Uncharacterized protein. (263 aa)
SOX8SRY-box transcription factor 8. (466 aa)
dlcDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
AHI1Abelson helper integration site 1. (747 aa)
TTC8Tetratricopeptide repeat domain 8. (516 aa)
MEGF11Multiple EGF like domains 11. (1085 aa)
crb1MSS51 mitochondrial translational activator. (1341 aa)
dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (740 aa)
rorbRadial spoke head protein 9 homolog. (505 aa)
crb2EMI domain containing 1. (1456 aa)
foxn4Fork-head domain-containing protein. (506 aa)
foxc1Forkhead box protein C1; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epi [...] (495 aa)
fjx1Y-box binding protein 1. (412 aa)
Rp1Uncharacterized protein. (297 aa)
pde6cPhosphodiesterase. (868 aa)
ntrk2Tyrosine-protein kinase receptor. (821 aa)
hao2-2Hydroxyacid oxidase 2 (long chain). (1011 aa)
PTF1APancreas associated transcription factor 1a. (320 aa)
calb1Stromal interaction molecule 1. (287 aa)
sox11Transcription factor Sox-11; Binds to the DNA sequence 5'-AACAAT-3'. Plays a role together with nlk in neural induction during early embryogenesis (By similarity). (383 aa)
SDK2Sidekick cell adhesion molecule 2. (2125 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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