(35 nodes) Cardiac muscle contraction network (Xenopus tropicalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tnni3	Transmembrane protein 256. (245 aa)
	kcne5	Uncharacterized protein. (103 aa)
	tnni2	Cytochrome b561. (188 aa)
	kcne3	Nebulin. (99 aa)
	csrp3	Cysteine and glycine-rich protein 2. (194 aa)
	SCN1B	Sodium voltage-gated channel beta subunit 1. (239 aa)
	Kcne1	Uncharacterized protein. (128 aa)
	taz	Tafazzin family protein; Belongs to the taffazin family. (257 aa)
	myl4	4-aminobutyrate aminotransferase. (190 aa)
	kcnq1	KRI1 homolog; Belongs to the potassium channel family. (659 aa)
	Tnni1	Uncharacterized protein. (152 aa)
	myl2	Adaptor related protein complex 5 subunit zeta 1. (245 aa)
	KCNE4	Potassium voltage-gated channel subfamily E regulatory subunit 4. (162 aa)
	ABCC9	ATP binding cassette subfamily C member 9. (1136 aa)
	ENSXETP00000022583	Uncharacterized protein. (113 aa)
	ENSXETP00000022765	Uncharacterized protein. (105 aa)
	map2k6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (435 aa)
	scn2b	Period circadian regulator 1. (220 aa)
	scn4b	Ig-like domain-containing protein. (237 aa)
	kcnj9	Uncharacterized protein. (419 aa)
	myl3	Myosin, light chain 3, alkali ventricular, skeletal, slow. (188 aa)
	slc9a1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (792 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2534 aa)
	KCNE2	Potassium voltage-gated channel subfamily E regulatory subunit 2. (119 aa)
	snta1	Outer dense fiber protein 3. (499 aa)
	NUP155	Nucleoporin 155. (1389 aa)
	nkx2-5	Toll-like receptor12. (300 aa)
	tnnc1	CTD small phosphatase like. (161 aa)
	cacna1g	Acyl-CoA synthetase long chain family member 1 protein. (2098 aa)
	pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1067 aa)
	kcnj5	Coiled-coil domain-containing 162. (404 aa)
	LOC100492908	Uncharacterized protein; Belongs to the potassium channel family. (687 aa)
	tcap	DNA topoisomerase II alpha. (186 aa)
	scn3b	Sodium channel, voltage-gated, type III, beta. (215 aa)
	myl10	LOC100170437 protein. (168 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KCNE2	KCNE4	ENSXETP00000033059	ENSXETP00000014333	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily E regulatory subunit 4.	0.796
KCNE2	LOC100492908	ENSXETP00000033059	ENSXETP00000045443	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Uncharacterized protein; Belongs to the potassium channel family.	0.544
KCNE2	kcne3	ENSXETP00000033059	ENSXETP00000003768	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Nebulin.	0.656
KCNE2	kcnq1	ENSXETP00000033059	ENSXETP00000009240	Potassium voltage-gated channel subfamily E regulatory subunit 2.	KRI1 homolog; Belongs to the potassium channel family.	0.544
KCNE2	scn4b	ENSXETP00000033059	ENSXETP00000027497	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Ig-like domain-containing protein.	0.562
KCNE2	snta1	ENSXETP00000033059	ENSXETP00000033951	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Outer dense fiber protein 3.	0.456
KCNE4	KCNE2	ENSXETP00000014333	ENSXETP00000033059	Potassium voltage-gated channel subfamily E regulatory subunit 4.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.796
KCNE4	Kcne1	ENSXETP00000014333	ENSXETP00000005788	Potassium voltage-gated channel subfamily E regulatory subunit 4.	Uncharacterized protein.	0.457
KCNE4	kcne3	ENSXETP00000014333	ENSXETP00000003768	Potassium voltage-gated channel subfamily E regulatory subunit 4.	Nebulin.	0.606
Kcne1	KCNE4	ENSXETP00000005788	ENSXETP00000014333	Uncharacterized protein.	Potassium voltage-gated channel subfamily E regulatory subunit 4.	0.457
Kcne1	LOC100492908	ENSXETP00000005788	ENSXETP00000045443	Uncharacterized protein.	Uncharacterized protein; Belongs to the potassium channel family.	0.679
Kcne1	kcne3	ENSXETP00000005788	ENSXETP00000003768	Uncharacterized protein.	Nebulin.	0.591
Kcne1	kcnq1	ENSXETP00000005788	ENSXETP00000009240	Uncharacterized protein.	KRI1 homolog; Belongs to the potassium channel family.	0.966
LOC100492908	KCNE2	ENSXETP00000045443	ENSXETP00000033059	Uncharacterized protein; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.544
LOC100492908	Kcne1	ENSXETP00000045443	ENSXETP00000005788	Uncharacterized protein; Belongs to the potassium channel family.	Uncharacterized protein.	0.679
LOC100492908	kcne3	ENSXETP00000045443	ENSXETP00000003768	Uncharacterized protein; Belongs to the potassium channel family.	Nebulin.	0.800
SCN1B	kcne3	ENSXETP00000005534	ENSXETP00000003768	Sodium voltage-gated channel beta subunit 1.	Nebulin.	0.577
SCN1B	scn2b	ENSXETP00000005534	ENSXETP00000027471	Sodium voltage-gated channel beta subunit 1.	Period circadian regulator 1.	0.937
SCN1B	scn4b	ENSXETP00000005534	ENSXETP00000027497	Sodium voltage-gated channel beta subunit 1.	Ig-like domain-containing protein.	0.969
Tnni1	csrp3	ENSXETP00000009729	ENSXETP00000005247	Uncharacterized protein.	Cysteine and glycine-rich protein 2.	0.456

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