STRINGSTRING
il1b il1b rnf10 rnf10 tnf tnf LOC101730668 LOC101730668 UFL1 UFL1 SKI SKI mecp2 mecp2 LOC100485014 LOC100485014 VEGFC VEGFC pdhx-2 pdhx-2 NF1 NF1 Il6 Il6 nf2 nf2 rb1 rb1 lyn lyn tp53 tp53 slc7a5 slc7a5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
il1bInterleukin-1; Belongs to the IL-1 family. (286 aa)
rnf10EGF like domain multiple 7. (754 aa)
tnfThyrotropin-releasing hormone receptor 3. (227 aa)
LOC101730668ABC transporter domain-containing protein. (310 aa)
UFL1UFM1 specific ligase 1. (794 aa)
SKISKI proto-oncogene. (719 aa)
mecp2Kruppel-like factor 17. (466 aa)
LOC100485014FERM domain-containing protein. (507 aa)
VEGFCVascular endothelial growth factor C. (407 aa)
pdhx-2Oxysterol binding protein like 10. (49 aa)
NF1Neurofibromin 1. (2812 aa)
Il6Uncharacterized protein. (150 aa)
nf2FERM domain-containing protein. (635 aa)
rb1Uncharacterized protein. (914 aa)
lynTyrosine-protein kinase. (524 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa)
slc7a5Dolichyl-phosphate mannosyltransferase polypeptide 3. (511 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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