STRINGSTRING
PDGFRB PDGFRB ambra1 ambra1 f2 f2 lyn lyn TEK TEK kdrl kdrl tgfb1 tgfb1 pdgfb-2 pdgfb-2 atg14 atg14 pik3r4 pik3r4 EPHA8 EPHA8 LOC101733520 LOC101733520 TNFAIP8L3 TNFAIP8L3 fgfr3 fgfr3 flt1 flt1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDGFRBPlatelet derived growth factor receptor beta. (1015 aa)
ambra1Suppressor of cytokine signaling 6. (1304 aa)
f2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (607 aa)
lynTyrosine-protein kinase. (524 aa)
TEKTEK receptor tyrosine kinase. (1114 aa)
kdrlUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1015 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
pdgfb-2Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
atg14Tripartite motif containing 62. (514 aa)
pik3r4Uncharacterized protein. (1361 aa)
EPHA8EPH receptor A8; Belongs to the protein kinase superfamily. Tyr protein kinase family. (503 aa)
LOC101733520C-C motif chemokine. (91 aa)
TNFAIP8L3TNF alpha induced protein 8 like 3. (202 aa)
fgfr3Fibroblast growth factor receptor. (829 aa)
flt1Keratin 18, gene 2. (970 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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