STRINGSTRING
lgals3 lgals3 slc30a1 slc30a1 homer1 homer1 plpp4 plpp4 cask cask pdgfb-2 pdgfb-2 trpv2 trpv2 PLN PLN pkd2 pkd2 ctnnb1 ctnnb1 WNK3 WNK3 stc1 stc1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lgals3Galectin. (256 aa)
slc30a1Solute carrier family 30 (Zinc transporter), member 1. (493 aa)
homer1Prolactin-releasing peptide receptor-like. (394 aa)
plpp4KIAA1522. (271 aa)
caskWW domain binding protein 11; Belongs to the MAGUK family. (926 aa)
pdgfb-2Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
trpv2Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; Belongs to the transient receptor (TC 1.A.4) family. (754 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
pkd2Ubiquitin carboxyl-terminal hydrolase 33. (951 aa)
ctnnb1Dynactin subunit 5. (788 aa)
WNK3Protein kinase domain-containing protein. (1624 aa)
stc1Serine/threonine kinase 16. (247 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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