STRINGSTRING
ARC ARC shisa9 shisa9 crh crh LOC100485454 LOC100485454 dlgap3 dlgap3 reln reln prrt1 prrt1 nptx2 nptx2 SHANK3 SHANK3 dlgap2 dlgap2 rasgrf1 rasgrf1 homer3 homer3 ifngr2.1 ifngr2.1 LOC108644813 LOC108644813 homer1 homer1 cacng3 cacng3 nsun2 nsun2 OPRM1 OPRM1 cacng7 cacng7 cnih2 cnih2 dlgap4 dlgap4 dlgap1 dlgap1 nptxr nptxr cacng8 cacng8 SHANK1 SHANK1 CNIH3 CNIH3 KLHL35 KLHL35 nap1l4 nap1l4 NETO1 NETO1 ifngr2.2 ifngr2.2 shisa8 shisa8 crhbp crhbp neto2 neto2 cacng2 cacng2 SHISA7 SHISA7 rasgrf2 rasgrf2 fes fes sult2b1-2 sult2b1-2 klhl24 klhl24
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARCActivity regulated cytoskeleton associated protein. (369 aa)
shisa9Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity). (390 aa)
crhCRF domain-containing protein. (207 aa)
LOC100485454CRF domain-containing protein. (226 aa)
dlgap3Uncharacterized protein. (999 aa)
relnG protein-coupled receptor 119. (3463 aa)
prrt1Sushi domain containing 2. (240 aa)
nptx2Nptx2 protein. (439 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1850 aa)
dlgap2Vacuolar protein sorting 4 homolog A. (973 aa)
rasgrf1DNA topoisomerase I, gene 2. (1240 aa)
homer3Rh-associated glycoprotein. (359 aa)
ifngr2.1Uncharacterized protein. (311 aa)
LOC108644813Uncharacterized protein. (300 aa)
homer1Prolactin-releasing peptide receptor-like. (394 aa)
cacng3EH domain containing 4. (317 aa)
nsun2RNA cytosine-C(5)-methyltransferase NSUN2; RNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Involved in various processes, such as epidermal stem cell differentiation, testis differentiation and maternal to zygotic transition during early development: acts by increasing protein synthesis; cytosine C(5)-methylation promoting tRNA stability and preventing mRNA decay. Methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) p [...] (798 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
cacng7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
cnih2Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs); Belongs to the cornichon family. (162 aa)
dlgap4Mitogen-activated protein kinase kinase kinase 8. (1071 aa)
dlgap1UTP18 small subunit processome component. (980 aa)
nptxrTrafficking protein particle complex 5. (479 aa)
cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (353 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1900 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (152 aa)
KLHL35Kelch like family member 35. (574 aa)
nap1l4Nucleosome assembly protein 1like 4. (321 aa)
NETO1Neuropilin and tolloid like 1. (529 aa)
ifngr2.2Lactamase beta. (337 aa)
shisa8Ring finger protein 216. (381 aa)
crhbpCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (321 aa)
neto2Uncharacterized protein. (525 aa)
cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
SHISA7Shisa family member 7. (504 aa)
rasgrf2CTD small phosphatase 1. (1232 aa)
fesVoltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (305 aa)
sult2b1-2Sec1 family domain containing 2. (113 aa)
klhl24DRE1 protein. (600 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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