STRINGSTRING
rab3gap2-2 rab3gap2-2 LOC100498570 LOC100498570 STAP1 STAP1 cdc42ep4 cdc42ep4 MYO10 MYO10 WNT1 WNT1 wasll wasll twf1 twf1 LOC101733520 LOC101733520 LOC105945216 LOC105945216 ccp110 ccp110 eps8 eps8 arf6 arf6 prkcd prkcd def8 def8 LOC733735 LOC733735 ARHGAP24 ARHGAP24 cdkl5 cdkl5 tchp tchp plekhm1 plekhm1 ripor2 ripor2 LOC100492960 LOC100492960 cdc42ep2 cdc42ep2 EPS8L2 EPS8L2 evl evl cav3.1 cav3.1 SYNE1 SYNE1 crocc2 crocc2 plce1 plce1 cav1 cav1 pgghg pgghg amy2a-2 amy2a-2 LOC101730247 LOC101730247 CROCC CROCC akirin1 akirin1 LOC100495736 LOC100495736 p2rx7 p2rx7 hpca-2 hpca-2 LOC100490828 LOC100490828 cyld cyld gpm6a gpm6a fam206a fam206a nrp1 nrp1 fmr1 fmr1 cobl cobl mstn.2 mstn.2 mstn.1 mstn.1 LOC733765 LOC733765 sdccag8 sdccag8 frmd7 frmd7 TENM1 TENM1 abi3 abi3 wasl wasl BCAS3 BCAS3 prkcq prkcq entr1 entr1 gdf11.1 gdf11.1 bag6 bag6 dync2li1 dync2li1 srf srf fam98a fam98a cdc42ep3 cdc42ep3 MYO3B MYO3B not not arhgap35 arhgap35 IFT88 IFT88 mapk15 mapk15 ndrg4 ndrg4 ift140 ift140 sh3yl1 sh3yl1 Map4 Map4 kif24 kif24 MPHOSPH9 MPHOSPH9 LOC101730772 LOC101730772 CEP97 CEP97 KLF5 KLF5 neurl1 neurl1 ndel1 ndel1 CYFIP1 CYFIP1 agrn agrn wasf2 wasf2 LOC100489307 LOC100489307 dmtn dmtn TAPT1 TAPT1 znf534 znf534 ANLN ANLN rab3ip rab3ip WDPCP WDPCP ENSXETP00000032157 ENSXETP00000032157 CDC42EP1 CDC42EP1 zmynd10 zmynd10 anln anln fxr1 fxr1 mtor mtor rhogl.1 rhogl.1 rhog rhog RCC2 RCC2 htt htt slf2-2 slf2-2 atg5 atg5 eps8l1 eps8l1 ENSXETP00000034866 ENSXETP00000034866 eps8l3 eps8l3 slit2 slit2 atmin atmin cdk10 cdk10 LOC100124990 LOC100124990 cdc42 cdc42 dpysl3 dpysl3 mcidas mcidas PALM PALM tgfbr1 tgfbr1 mien1 mien1 LOC733841 LOC733841 brk1 brk1 wrap73 wrap73 CCDC151 CCDC151 cav3.2 cav3.2 myo10.2 myo10.2 bin3 bin3 fam98a-2 fam98a-2 podxl podxl LOC100498287 LOC100498287 LOC108644450 LOC108644450 vdac3 vdac3 LOC101734050 LOC101734050 clrn1 clrn1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rab3gap2-2F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (219 aa)
LOC100498570Uncharacterized protein. (312 aa)
STAP1Signal transducing adaptor family member 1. (216 aa)
cdc42ep4CDC42 effector protein (Rho GTPase binding) 4. (305 aa)
MYO10Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2079 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
wasllCut like homeobox 1. (404 aa)
twf1Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). (353 aa)
LOC101733520C-C motif chemokine. (91 aa)
LOC105945216U2 small nuclear RNA auxiliary factor 1. (275 aa)
ccp110Hippocalcin-like protein 1. (962 aa)
eps8SH3 domain-containing protein. (763 aa)
arf6Solute carrier family 8 (sodium/calcium exchanger), member 1; Belongs to the small GTPase superfamily. Arf family. (229 aa)
prkcdProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)
def8Differentially expressed in FDCP 8 homolog; Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption. (456 aa)
LOC733735CRIB domain-containing protein. (304 aa)
ARHGAP24Rho GTPase activating protein 24. (738 aa)
cdkl5Very low density lipoprotein receptor. (1043 aa)
tchpUncharacterized protein. (563 aa)
plekhm1Protein phosphatase 3, catalytic subunit, alpha isozyme. (1061 aa)
ripor2PL48 domain-containing protein. (1063 aa)
LOC100492960Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (332 aa)
cdc42ep2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (213 aa)
EPS8L2EPS8 like 2. (678 aa)
evlSolute carrier family 30 (zinc transporter), member 9. (712 aa)
cav3.1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
SYNE1Spectrin repeat containing nuclear envelope protein 1. (8694 aa)
crocc2Phosphoglucomutase 2. (1978 aa)
plce1Phosphoinositide phospholipase C. (2207 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
pgghgProtein-glucosylgalactosylhydroxylysine glucosidase. (245 aa)
amy2a-2Amylase, alpha 2A (pancreatic). (199 aa)
LOC101730247Receptor (G protein-coupled) activity modifying protein 3. (561 aa)
CROCCCiliary rootlet coiled-coil, rootletin. (1439 aa)
akirin1Akirin-1. (186 aa)
LOC100495736Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (310 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (558 aa)
hpca-2Hippocalcin. (2630 aa)
LOC100490828P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (559 aa)
cyldTLR4 interactor with leucine-rich repeats; Belongs to the peptidase C19 family. (975 aa)
gpm6aGlycoprotein M6A. (278 aa)
fam206aProtein Abitram; May regulate actin polymerization, filopodia dynamics and arborization of neurons. (236 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (926 aa)
fmr1Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. (590 aa)
coblEgl-9 family hypoxia-inducible factor 3. (500 aa)
mstn.2Ubiquitin associated protein 2. (374 aa)
mstn.1Lin-37 DREAM MuvB core complex component. (369 aa)
LOC733765Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
sdccag8Calpain 2, gene2. (591 aa)
frmd7Nystagmus 1 protein. (311 aa)
TENM1Teneurin transmembrane protein 1. (2761 aa)
abi3Abi_HHR domain-containing protein. (337 aa)
waslWiskott-Aldrich syndrome-like. (511 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (858 aa)
prkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (554 aa)
entr1Endosome-associated-trafficking regulator 1; Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Belongs to the ENTR1 family. (346 aa)
gdf11.1ATR interacting protein. (425 aa)
bag6Large proline-rich protein bag6; ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the bag6/bat3 complex, which maintains these client proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endo [...] (1135 aa)
dync2li1Uncharacterized protein. (341 aa)
srfHydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7. (359 aa)
fam98aMeiotic nuclear divisions 1. (387 aa)
cdc42ep3CDC42 effector protein (Rho GTPase binding) 3. (254 aa)
MYO3BMyosin IIIB. (1292 aa)
notHomeobox domain-containing protein. (236 aa)
arhgap35Bora, aurora kinase A activator. (1472 aa)
IFT88Intraflagellar transport 88. (826 aa)
mapk15Mitogen-activated protein kinase. (590 aa)
ndrg4Protein NDRG4; Contributes to the maintenance of intracerebral BDNF levels within the normal range. May enhance growth factor-induced ERK1 and ERK2 phosphorylation. May attenuate growth factor-promoted ELK1 phosphorylation in a microtubule-dependent manner (By similarity). Belongs to the NDRG family. (407 aa)
ift140Uncharacterized protein. (1461 aa)
sh3yl1Tetratricopeptide repeat domain 1. (344 aa)
Map4Microtubule-associated protein. (2108 aa)
kif24Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (910 aa)
MPHOSPH9M-phase phosphoprotein 9. (1133 aa)
LOC101730772Armadillo repeat containing 4; Belongs to the protein kinase superfamily. (345 aa)
CEP97Centrosomal protein 97. (813 aa)
KLF5Kruppel like factor 5. (434 aa)
neurl1Neurl protein. (555 aa)
ndel1Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. (345 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1272 aa)
agrnSOS Ras/Rac guanine nucleotide exchange factor 1. (2105 aa)
wasf2Forkhead box Q1. (484 aa)
LOC100489307Dynein, axonemal, heavy chain 2; Belongs to the peptidase C19 family. (757 aa)
dmtnHP domain-containing protein. (416 aa)
TAPT1Transmembrane anterior posterior transformation 1. (549 aa)
znf534Uncharacterized protein. (423 aa)
ANLNAnillin actin binding protein. (1113 aa)
rab3ipSec2p domain-containing protein. (469 aa)
WDPCPWD repeat containing planar cell polarity effector. (708 aa)
ENSXETP00000032157Ion_trans domain-containing protein. (263 aa)
CDC42EP1CRIB domain-containing protein. (321 aa)
zmynd10Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (455 aa)
anlnPH domain-containing protein. (873 aa)
fxr1Fragile X mental retardation syndrome-related protein 1 homolog; RNA-binding protein. Binds poly(G) and poly(U) but not poly(A) or poly(C). Regulates somite formation, probably by regulating gene expression (By similarity). (674 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2534 aa)
rhogl.1Uncharacterized protein. (191 aa)
rhogUncharacterized protein. (191 aa)
RCC2Regulator of chromosome condensation 2. (447 aa)
httDihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). (3110 aa)
slf2-2SMC5-SMC6 complex localization factor 2. (338 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
eps8l1Galanin receptor 1. (724 aa)
ENSXETP00000034866Transmembrane protein 17; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (304 aa)
eps8l3SH3 domain-containing protein. (566 aa)
slit2ATPase family, AAA domain containing 3A. (1564 aa)
atminNeuronal differentiation 1. (763 aa)
cdk10Uncharacterized protein. (638 aa)
LOC100124990Rho GTPase activating protein 20. (234 aa)
cdc42Uncharacterized protein. (212 aa)
dpysl3Dihydropyrimidinase-related protein 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity). (673 aa)
mcidasMulticilin; Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing e2f4 and e2f5 that binds and activate genes required for centriole biogenesis. Activates genes required for centriole assembly (plk4, cep152) and genes specifically required for motile cilia formation (foxj1). Also promotes the deuterosome pathway of centriole biogenesis by activating expression of deup1, but not its paralog cep63; Belongs to the geminin family. (376 aa)
PALMParalemmin. (369 aa)
tgfbr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
mien1Uncharacterized protein. (95 aa)
LOC733841Adaptor related protein complex 1 subunit gamma 1. (331 aa)
brk1Anoctamin 9. (170 aa)
wrap73Uncharacterized protein. (451 aa)
CCDC151Coiled-coil domain containing 151. (562 aa)
cav3.2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
myo10.2Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1991 aa)
bin3BAR domain-containing protein. (267 aa)
fam98a-2Calpain 15. (548 aa)
podxlGamma-aminobutyric acid (GABA) B receptor, 1. (459 aa)
LOC100498287Protein kinase C beta type; Belongs to the protein kinase superfamily. (323 aa)
LOC108644450Zinc transporter ZIP14. (641 aa)
vdac3Uncharacterized protein. (299 aa)
LOC101734050Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (287 aa)
clrn1Kelch like family member 17. (232 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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