(36 nodes) Regulation of cilium assembly network (Xenopus tropicalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	entr1	Endosome-associated-trafficking regulator 1; Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Belongs to the ENTR1 family. (346 aa)
	LOC100498570	Uncharacterized protein. (312 aa)
	ccp110	Hippocalcin-like protein 1. (962 aa)
	cdkl5	Very low density lipoprotein receptor. (1043 aa)
	tchp	Uncharacterized protein. (563 aa)
	LOC101730247	Receptor (G protein-coupled) activity modifying protein 3. (561 aa)
	CROCC	Ciliary rootlet coiled-coil, rootletin. (1439 aa)
	hpca-2	Hippocalcin. (2630 aa)
	dync2li1	Uncharacterized protein. (341 aa)
	not	Homeobox domain-containing protein. (236 aa)
	arhgap35	Bora, aurora kinase A activator. (1472 aa)
	IFT88	Intraflagellar transport 88. (826 aa)
	mapk15	Mitogen-activated protein kinase. (590 aa)
	ndrg4	Protein NDRG4; Contributes to the maintenance of intracerebral BDNF levels within the normal range. May enhance growth factor-induced ERK1 and ERK2 phosphorylation. May attenuate growth factor-promoted ELK1 phosphorylation in a microtubule-dependent manner (By similarity). Belongs to the NDRG family. (407 aa)
	ift140	Uncharacterized protein. (1461 aa)
	Map4	Microtubule-associated protein. (2108 aa)
	kif24	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (910 aa)
	MPHOSPH9	M-phase phosphoprotein 9. (1133 aa)
	CEP97	Centrosomal protein 97. (813 aa)
	LOC100489307	Dynein, axonemal, heavy chain 2; Belongs to the peptidase C19 family. (757 aa)
	TAPT1	Transmembrane anterior posterior transformation 1. (549 aa)
	zmynd10	Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (455 aa)
	htt	Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). (3110 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	ENSXETP00000034866	Transmembrane protein 17; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (304 aa)
	atmin	Neuronal differentiation 1. (763 aa)
	cdk10	Uncharacterized protein. (638 aa)
	mcidas	Multicilin; Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing e2f4 and e2f5 that binds and activate genes required for centriole biogenesis. Activates genes required for centriole assembly (plk4, cep152) and genes specifically required for motile cilia formation (foxj1). Also promotes the deuterosome pathway of centriole biogenesis by activating expression of deup1, but not its paralog cep63; Belongs to the geminin family. (376 aa)
	wrap73	Uncharacterized protein. (451 aa)
	CCDC151	Coiled-coil domain containing 151. (562 aa)
	LOC108644450	Zinc transporter ZIP14. (641 aa)
	vdac3	Uncharacterized protein. (299 aa)
	SYNE1	Spectrin repeat containing nuclear envelope protein 1. (8694 aa)
	crocc2	Phosphoglucomutase 2. (1978 aa)
	cyld	TLR4 interactor with leucine-rich repeats; Belongs to the peptidase C19 family. (975 aa)
	sdccag8	Calpain 2, gene2. (591 aa)

Your Current Organism:

Xenopus tropicalis

NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEP97	ccp110	ENSXETP00000024882	ENSXETP00000004882	Centrosomal protein 97.	Hippocalcin-like protein 1.	0.414
ENSXETP00000034866	ccp110	ENSXETP00000034866	ENSXETP00000004882	Transmembrane protein 17; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Hippocalcin-like protein 1.	0.516
ENSXETP00000034866	kif24	ENSXETP00000034866	ENSXETP00000023517	Transmembrane protein 17; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.874
IFT88	LOC100498570	ENSXETP00000021354	ENSXETP00000001224	Intraflagellar transport 88.	Uncharacterized protein.	0.424
IFT88	dync2li1	ENSXETP00000021354	ENSXETP00000017460	Intraflagellar transport 88.	Uncharacterized protein.	0.424
IFT88	ift140	ENSXETP00000021354	ENSXETP00000021592	Intraflagellar transport 88.	Uncharacterized protein.	0.843
LOC100498570	IFT88	ENSXETP00000001224	ENSXETP00000021354	Uncharacterized protein.	Intraflagellar transport 88.	0.424
LOC100498570	ift140	ENSXETP00000001224	ENSXETP00000021592	Uncharacterized protein.	Uncharacterized protein.	0.471
atg5	htt	ENSXETP00000034480	ENSXETP00000034356	Autophagy protein 5; Involved in autophagic vesicle formation.	Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex).	0.530
ccp110	CEP97	ENSXETP00000004882	ENSXETP00000024882	Hippocalcin-like protein 1.	Centrosomal protein 97.	0.414
ccp110	ENSXETP00000034866	ENSXETP00000004882	ENSXETP00000034866	Hippocalcin-like protein 1.	Transmembrane protein 17; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.516
ccp110	entr1	ENSXETP00000004882	ENSXETP00000052546	Hippocalcin-like protein 1.	Endosome-associated-trafficking regulator 1; Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Belongs to the ENTR1 family.	0.558
ccp110	kif24	ENSXETP00000004882	ENSXETP00000023517	Hippocalcin-like protein 1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.516
ccp110	mcidas	ENSXETP00000004882	ENSXETP00000037329	Hippocalcin-like protein 1.	Multicilin; Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing e2f4 and e2f5 that binds and activate genes required for centriole biogenesis. Activates genes required for centriole assembly (plk4, cep152) and genes specifically required for motile cilia formation (foxj1). Also promotes the deuterosome pathway of centriole biogenesis by activating expression of deup1, but not its paralog cep63; Belongs to the geminin family.	0.468
crocc2	wrap73	ENSXETP00000047510	ENSXETP00000039153	Phosphoglucomutase 2.	Uncharacterized protein.	0.459
dync2li1	IFT88	ENSXETP00000017460	ENSXETP00000021354	Uncharacterized protein.	Intraflagellar transport 88.	0.424
dync2li1	ift140	ENSXETP00000017460	ENSXETP00000021592	Uncharacterized protein.	Uncharacterized protein.	0.471
entr1	ccp110	ENSXETP00000052546	ENSXETP00000004882	Endosome-associated-trafficking regulator 1; Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Belongs to the ENTR1 family.	Hippocalcin-like protein 1.	0.558
htt	atg5	ENSXETP00000034356	ENSXETP00000034480	Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex).	Autophagy protein 5; Involved in autophagic vesicle formation.	0.530
ift140	IFT88	ENSXETP00000021592	ENSXETP00000021354	Uncharacterized protein.	Intraflagellar transport 88.	0.843

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