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ptbp1 ptbp1 LOC100498620 LOC100498620 cirbp cirbp sap18 sap18 ACIN1 ACIN1 elavl1 elavl1 traf5 traf5 usp7-2 usp7-2 pdk1 pdk1 angel2 angel2 tent5c tent5c e2f1 e2f1 gdnf gdnf dhx34 dhx34 C1QBP C1QBP srsf9 srsf9 tirap tirap LOC100491693 LOC100491693 igf2bp3 igf2bp3 rbm38 rbm38 traf3ip3 traf3ip3 rbm46 rbm46 ptbp3 ptbp3 rbm20 rbm20 mapkapk2 mapkapk2 ZC3H14 ZC3H14 srsf7 srsf7 thrap3 thrap3 fus fus hnrnpd hnrnpd taf15 taf15 TENT5A TENT5A tent5b tent5b A1CF A1CF LOC100488959 LOC100488959 PKP1 PKP1 u2af2 u2af2 dhx9 dhx9 ybx1 ybx1 SFSWAP SFSWAP pabpc1l pabpc1l hnrnpab hnrnpab PKP3 PKP3 noct noct dnd1 dnd1 TENT4B TENT4B eif4enif1 eif4enif1 TENT5D TENT5D VIP VIP hnrnpc hnrnpc larp1 larp1 meioc meioc bub1-2 bub1-2 rbm24 rbm24 nbas nbas dazl dazl
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ptbp1Uncharacterized protein. (569 aa)
LOC100498620Uncharacterized protein. (533 aa)
cirbpCold-inducible RNA-binding protein; Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to themm and inhibiting their deadenylation. Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules, and cell movement during embryogenesis. Required for pronephros development (By similarity). (198 aa)
sap18Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (153 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1951 aa)
elavl1ELAV-like protein 1; RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (By similarity). Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Acts cooperatively with cribp to stabilize AU-rich sequence (ARE)-containing mRNAs. May play a role during gastrulation. Required for the vegetal localization of vg1 mRNA (By similarity). (336 aa)
traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (539 aa)
usp7-2Ubiquitin specific peptidase 7 (herpes virus-associated). (316 aa)
pdk1Pyruvate dehydrogenase kinase 1. (167 aa)
angel2La ribonucleoprotein domain family member 4. (526 aa)
tent5cTTK protein kinase. (393 aa)
e2f1TEA domain family member 1 (SV40 transcriptional enhancer factor). (428 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (227 aa)
dhx34Uncharacterized protein. (1142 aa)
C1QBPComplement C1q binding protein. (272 aa)
srsf9Splicing factor, arginine/serine-rich 9. (225 aa)
tirapTIR domain-containing protein. (547 aa)
LOC100491693TIR domain-containing protein. (505 aa)
igf2bp3Uncharacterized protein. (600 aa)
rbm38RNA-binding protein 38; RNA-binding protein that specifically bind the 3'-UTR of VegT transcripts, leading to maintain their stability and stimulate their translation, thereby playing a role in germ layer formation. VegT is a localized maternal determinant essentially required for endoderm formation. Also has some proneural function in the open neural plate and in the context of retinogenesis. May also act as a mRNA splicing factor. May play a role in myogenic differentiation (By similarity). Belongs to the RBM38 family. (219 aa)
traf3ip3TRAF3 interacting protein 2. (333 aa)
rbm46Probable RNA-binding protein 46. (534 aa)
ptbp3Translational activator of mitochondrially encoded cytochrome c oxidase I. (568 aa)
rbm20Par-6 family cell polarity regulator beta. (1064 aa)
mapkapk2F-box and WD repeat domain containing 5; Belongs to the protein kinase superfamily. (412 aa)
ZC3H14Zinc finger CCCH-type containing 14. (743 aa)
srsf7Spermine synthase. (234 aa)
thrap3Uncharacterized protein. (919 aa)
fusUncharacterized protein. (547 aa)
hnrnpdADAM metallopeptidase domain 17. (295 aa)
taf15Uncharacterized protein. (501 aa)
TENT5ATerminal nucleotidyltransferase 5A. (402 aa)
tent5bUncharacterized protein. (395 aa)
A1CFAPOBEC1 complementation factor. (592 aa)
LOC100488959Pumilio RNA binding family member 3. (856 aa)
PKP1Plakophilin 1. (686 aa)
u2af2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (469 aa)
dhx9U4/U6 small nuclear ribonucleoprotein Prp31. (1257 aa)
ybx13-hydroxy-3-methylglutaryl-CoA synthase 1. (314 aa)
SFSWAPSplicing factor SWAP. (932 aa)
pabpc1lEmbryonic polyadenylate-binding protein; Binds and protects the poly(A) tail of mRNA with or without an AU-rich element (ARE) and prevents mRNA deadenylation. Stimulates the translation of mRNAs to which it is bound during early development (By similarity). (635 aa)
hnrnpabCentrosomal protein 112kDa. (326 aa)
PKP3Plakophilin 3. (819 aa)
noctCCR4 carbon catabolite repression 4-like (S. cerevisiae). (458 aa)
dnd1Dead end homolog 1 (Zebrafish). (373 aa)
TENT4BTerminal nucleotidyltransferase 4B. (650 aa)
eif4enif1Uncharacterized protein. (957 aa)
TENT5DTerminal nucleotidyltransferase 5D. (398 aa)
VIPVasoactive intestinal peptide. (202 aa)
hnrnpcCeramide synthase 1. (327 aa)
larp1HTH La-type RNA-binding domain-containing protein. (1022 aa)
meiocUncharacterized protein. (801 aa)
bub1-2Tumor necrosis factor alpha-induced protein 8. (748 aa)
rbm24RNA-binding protein 24; Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embry [...] (226 aa)
nbasGTP binding protein 4. (2373 aa)
dazlDeleted in azoospermia-like; RNA-binding protein that is required for primordial germ cell (PGC) differentiation and indirectly necessary for the migration of PGCs through the endoderm. May promote meiotic cell division during spermatogenesis. Shows a preference for G- and U-rich RNAs and probably binds the 3'-UTR of target mRNAs. Stimulates the initiation of translation of mRNAs through the recruitment of poly(A)-binding proteins (PABPs) (By similarity). (286 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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