STRINGSTRING
psmc6 psmc6 taf13 taf13 sub1 sub1 med1l med1l plxna3 plxna3 gtf2a1 gtf2a1 JUN JUN med30 med30 TAF6 TAF6 srf srf taf4 taf4 ercc1 ercc1 taf12 taf12 FOSL1 FOSL1 TAF2 TAF2 HNF1B HNF1B SETX SETX DHX36 DHX36 jund.2 jund.2 nkx2-5 nkx2-5 tp53 tp53 gtf2a2 gtf2a2 med14 med14 clec3b-2 clec3b-2 med24 med24 TAF3 TAF3 esr1 esr1 bclaf1 bclaf1 med13 med13 TAF4B TAF4B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
psmc6AAA domain-containing protein; Belongs to the AAA ATPase family. (419 aa)
taf13Sorting and assembly machinery component 50 homolog. (144 aa)
sub1Activated RNA polymerase II transcription cofactor 4. (128 aa)
med1lMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (678 aa)
plxna3Plexin A3. (49 aa)
gtf2a1General transcription factor IIA, 1. (367 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (312 aa)
med30Uncharacterized protein. (184 aa)
TAF6TATA-box binding protein associated factor 6. (395 aa)
srfHydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7. (359 aa)
taf4Centrin 4. (1045 aa)
ercc1Uncharacterized protein. (302 aa)
taf12Microtubule associated serine/threonine kinase 1. (218 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (298 aa)
TAF2TATA-box binding protein associated factor 2. (1191 aa)
HNF1BHNF1 homeobox B. (566 aa)
SETXSenataxin. (2535 aa)
DHX36DEAH-box helicase 36. (1006 aa)
jund.2mRNA export factor. (448 aa)
nkx2-5Toll-like receptor12. (300 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa)
gtf2a2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
med14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1460 aa)
clec3b-2Uncharacterized protein. (1371 aa)
med24Phosphatidylinositol transfer protein beta. (990 aa)
TAF3TATA-box binding protein associated factor 3. (929 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
bclaf1Btz domain-containing protein. (894 aa)
med13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2169 aa)
TAF4BTATA-box binding protein associated factor 4b. (892 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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