STRINGSTRING
srebf1 srebf1 tnf tnf drosha drosha mrtfa mrtfa nfatc3 nfatc3 SMAD6 SMAD6 NFATC4 NFATC4 JUN JUN mrtfb mrtfb TGFB2 TGFB2 gnl3 gnl3 zswim8 zswim8 ppara ppara srf srf stat3.2 stat3.2 pdgfb-2 pdgfb-2 stat3.1 stat3.1 GATA2 GATA2 apln apln tert tert srebf2 srebf2 il10 il10 FOSL1 FOSL1 KLF5 KLF5 nradd nradd znf534 znf534 jund.2 jund.2 smad4.1 smad4.1 tent2 tent2 lin28b lin28b ATOH8 ATOH8 pnpt1 pnpt1 tp53 tp53 smad1 smad1 gata3 gata3 REST REST RC3H1 RC3H1 myocd myocd idi1-2 idi1-2 Zc3h12a Zc3h12a myc myc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
srebf1BHLH domain-containing protein. (1106 aa)
tnfThyrotropin-releasing hormone receptor 3. (227 aa)
droshaKruppel-like factor 8. (1382 aa)
mrtfaMyotubularin related protein 1. (1053 aa)
nfatc3Galectin 9. (894 aa)
SMAD6Mothers against decapentaplegic homolog. (352 aa)
NFATC4Nuclear factor of activated T cells 4. (1091 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (312 aa)
mrtfbSAP domain-containing protein. (1079 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
gnl3Receptor tyrosine kinase like orphan receptor 2. (472 aa)
zswim8Agrin. (1830 aa)
pparaLysosomal-associated membrane protein 1. (474 aa)
srfHydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7. (359 aa)
stat3.2STAT_int domain-containing protein. (408 aa)
pdgfb-2Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa)
stat3.1Signal transducer and activator of transcription. (715 aa)
GATA2GATA binding protein 2. (462 aa)
aplnLOC100135238 protein. (76 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1196 aa)
srebf2BHLH domain-containing protein. (1104 aa)
il10Activating transcription factor 6. (172 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (298 aa)
KLF5Kruppel like factor 5. (434 aa)
nraddHigh mobility group box 3. (390 aa)
znf534Uncharacterized protein. (423 aa)
jund.2mRNA export factor. (448 aa)
smad4.1Mothers against decapentaplegic homolog. (579 aa)
tent2Poly(A) RNA polymerase GLD2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs during oocyte maturation. Plays a central role during oocyte maturation by mediating polyadenylation of dormant mRNAs, which contain 5'AAUAAA-3' sequence in their 3'-UTR. In immature oocytes, polyadenylation of poly(A) tails is counteracted by the ribonuclease parn. During maturation parn is excluded from the ribonucleoprote [...] (492 aa)
lin28bCCHC-type domain-containing protein. (277 aa)
ATOH8Atonal bHLH transcription factor 8. (246 aa)
pnpt1F-box DNA helicase 1. (789 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa)
smad1Mothers against decapentaplegic homolog. (464 aa)
gata3Uncharacterized protein. (454 aa)
RESTRE1 silencing transcription factor. (1442 aa)
RC3H1Ring finger and CCCH-type domains 1. (1123 aa)
myocdYip1 domain family member 1. (956 aa)
idi1-2Isopentenyl-diphosphate delta isomerase 1. (290 aa)
Zc3h12aC3H1-type domain-containing protein. (349 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (418 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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