node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Il6 | stat3.1 | ENSXETP00000024453 | ENSXETP00000019558 | Uncharacterized protein. | Signal transducer and activator of transcription. | 0.539 |
Il6 | stat3.2 | ENSXETP00000024453 | ENSXETP00000018942 | Uncharacterized protein. | STAT_int domain-containing protein. | 0.539 |
Il6 | tp53 | ENSXETP00000024453 | ENSXETP00000041856 | Uncharacterized protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.443 |
PUM2 | fmr1 | ENSXETP00000026601 | ENSXETP00000015179 | Pumilio RNA binding family member 2. | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. | 0.420 |
TRUB1 | ddx5 | ENSXETP00000027437 | ENSXETP00000034234 | TruB pseudouridine synthase family member 1. | Uncharacterized protein; Belongs to the DEAD box helicase family. | 0.515 |
ddx5 | TRUB1 | ENSXETP00000034234 | ENSXETP00000027437 | Uncharacterized protein; Belongs to the DEAD box helicase family. | TruB pseudouridine synthase family member 1. | 0.515 |
ddx5 | dhx9 | ENSXETP00000034234 | ENSXETP00000032394 | Uncharacterized protein; Belongs to the DEAD box helicase family. | U4/U6 small nuclear ribonucleoprotein Prp31. | 0.769 |
ddx5 | tp53 | ENSXETP00000034234 | ENSXETP00000041856 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.828 |
dhx9 | ddx5 | ENSXETP00000032394 | ENSXETP00000034234 | U4/U6 small nuclear ribonucleoprotein Prp31. | Uncharacterized protein; Belongs to the DEAD box helicase family. | 0.769 |
fmr1 | PUM2 | ENSXETP00000015179 | ENSXETP00000026601 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. | Pumilio RNA binding family member 2. | 0.420 |
fmr1 | fxr1 | ENSXETP00000015179 | ENSXETP00000032646 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. | Fragile X mental retardation syndrome-related protein 1 homolog; RNA-binding protein. Binds poly(G) and poly(U) but not poly(A) or poly(C). Regulates somite formation, probably by regulating gene expression (By similarity). | 0.973 |
fxr1 | fmr1 | ENSXETP00000032646 | ENSXETP00000015179 | Fragile X mental retardation syndrome-related protein 1 homolog; RNA-binding protein. Binds poly(G) and poly(U) but not poly(A) or poly(C). Regulates somite formation, probably by regulating gene expression (By similarity). | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. | 0.973 |
stat3.1 | Il6 | ENSXETP00000019558 | ENSXETP00000024453 | Signal transducer and activator of transcription. | Uncharacterized protein. | 0.539 |
stat3.1 | tp53 | ENSXETP00000019558 | ENSXETP00000041856 | Signal transducer and activator of transcription. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.502 |
stat3.2 | Il6 | ENSXETP00000018942 | ENSXETP00000024453 | STAT_int domain-containing protein. | Uncharacterized protein. | 0.539 |
stat3.2 | tp53 | ENSXETP00000018942 | ENSXETP00000041856 | STAT_int domain-containing protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.502 |
tp53 | Il6 | ENSXETP00000041856 | ENSXETP00000024453 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Uncharacterized protein. | 0.443 |
tp53 | ddx5 | ENSXETP00000041856 | ENSXETP00000034234 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Uncharacterized protein; Belongs to the DEAD box helicase family. | 0.828 |
tp53 | stat3.1 | ENSXETP00000041856 | ENSXETP00000019558 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Signal transducer and activator of transcription. | 0.502 |
tp53 | stat3.2 | ENSXETP00000041856 | ENSXETP00000018942 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | STAT_int domain-containing protein. | 0.502 |