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ENSXETP00000016475 | Uncharacterized protein. (193 aa) | ||||
itm2b | Integral membrane protein 2B. (257 aa) | ||||
renbp | Coenzyme Q8B. (414 aa) | ||||
sar1a | Lectin, galactoside-binding, soluble, 4, gene 2; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) | ||||
slc32a1 | Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Belongs to the amino acid/polyamine transporter 2 family. (518 aa) | ||||
FRMPD4 | FERM and PDZ domain containing 4. (1292 aa) | ||||
rab9a | Vasodilator stimulated phosphoprotein. (201 aa) | ||||
atp6v0c | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (156 aa) | ||||
tpst1-2 | Nocturnin. (447 aa) | ||||
abcg2 | Calcium and integrin binding 1. (660 aa) | ||||
foxp4 | T-box transcription factor TBX20. (658 aa) | ||||
SORT1 | Sortilin. (801 aa) | ||||
ehmt1-2 | Uncharacterized protein. (207 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7. (594 aa) | ||||
pdcd6 | Programmed cell death 6. (182 aa) | ||||
sycn-2 | LOC100127766 protein. (131 aa) | ||||
FIG4 | FIG4 phosphoinositide 5-phosphatase. (741 aa) | ||||
clk1 | Dickkopf WNT signaling pathway inhibitor 3; Belongs to the protein kinase superfamily. (481 aa) | ||||
rgs14 | Regulator of G protein signaling 14. (746 aa) | ||||
pigk | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (427 aa) | ||||
FRMPD3 | FERM and PDZ domain containing 3. (1608 aa) | ||||
rexo1 | Crystallin beta A2. (1129 aa) | ||||
irf3 | Transmembrane 6 superfamily member 2. (470 aa) | ||||
vamp4 | Vesicle-associated membrane protein 4. (141 aa) | ||||
ankle1 | Uncharacterized protein. (1380 aa) | ||||
LOC100493529 | Leucine zipper protein 2. (425 aa) | ||||
ptch1 | Patched 1. (339 aa) | ||||
cdip1 | Cell death-inducing p53-target protein 1; May act as a p53/TP53-apoptotic effector. (207 aa) | ||||
necap2 | DUF1681 domain-containing protein. (154 aa) | ||||
atp6v1d | Vasculin. (247 aa) | ||||
lamtor1 | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). (157 aa) | ||||
cradd.2-2 | Phospholipase A2 group III. (137 aa) | ||||
aldh1a1 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (526 aa) | ||||
oca2 | cAMP responsive element binding protein 1. (858 aa) | ||||
INPPL1 | Inositol polyphosphate phosphatase like 1. (925 aa) | ||||
LHFPL2 | LHFPL tetraspan subfamily member 2. (225 aa) | ||||
scamp1 | Secretory carrier-associated membrane protein. (355 aa) | ||||
clcn3 | Chloride channel protein. (867 aa) | ||||
slc11a1 | T-box 4. (340 aa) | ||||
lamtor5 | Ragulator complex protein LAMTOR5; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). (91 aa) | ||||
AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1097 aa) | ||||
rab35l | Uncharacterized protein. (201 aa) | ||||
cope | Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (315 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (908 aa) | ||||
rab31 | Non-SMC condensin I complex subunit D2. (206 aa) | ||||
RPH3A | Rabphilin 3A. (693 aa) | ||||
dct | Uncharacterized protein. (518 aa) | ||||
ptk2b | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1017 aa) | ||||
pld2 | Phospholipase. (985 aa) | ||||
aftph | Transmembrane protein 104. (131 aa) | ||||
rab3a | RAB3A, member RAS oncogene family. (220 aa) | ||||
pikfyve | Uncharacterized protein. (2104 aa) | ||||
stbd1 | CBM20 domain-containing protein. (418 aa) | ||||
cpe | Uncharacterized protein. (467 aa) | ||||
dipk2a | Divergent protein kinase domain 2A; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade; Belongs to the DIPK family. (431 aa) | ||||
plvap | Uncharacterized protein. (366 aa) | ||||
VPS13B | Vacuolar protein sorting 13 homolog B. (4027 aa) | ||||
vamp1 | Isocitrate dehydrogenase 1 (NADP+). (110 aa) | ||||
LOC100495031 | Uncharacterized protein. (779 aa) | ||||
slc30a6-2 | Zinc transporter 6. (1103 aa) | ||||
arrdc3 | Tetratricopeptide repeat protein 30A. (412 aa) | ||||
crp.2 | Pentaxin. (240 aa) | ||||
slc17a7 | Vesicular glutamate transporter 1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. (594 aa) | ||||
vopp1 | Vesicular, overexpressed in cancer, prosurvival protein 1; May be involved in the transcriptional activity of NFKB1. Belongs to the VOPP1/ECOP family. (167 aa) | ||||
syp | LOC100144928 protein. (300 aa) | ||||
acy3-2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming). (340 aa) | ||||
SNX8 | Sorting nexin 8. (432 aa) | ||||
ap1b1 | AP complex subunit beta. (946 aa) | ||||
sec24b | CaM kinase-like vesicle-associated. (1103 aa) | ||||
slc29a3 | Uncharacterized protein. (254 aa) | ||||
LOC100496796 | Stonin 2. (367 aa) | ||||
LOC100491292 | Xyloside xylosyltransferase 1. (798 aa) | ||||
slc22a4 | MFS domain-containing protein. (555 aa) | ||||
dnajc5g | DIRAS family GTP binding RAS like 1. (232 aa) | ||||
SYNPR | Synaptoporin. (283 aa) | ||||
sycn | Phosphodiesterase 5A. (131 aa) | ||||
LOC100491589 | RabBD domain-containing protein. (357 aa) | ||||
KLHL12 | Kelch like family member 12. (599 aa) | ||||
lamp1 | Uncharacterized protein. (429 aa) | ||||
ZPLD1 | Zona pellucida like domain containing 1. (407 aa) | ||||
doc2b | Double C2-like domain-containing protein. (402 aa) | ||||
colgalt2 | Uncharacterized protein. (616 aa) | ||||
lamp3 | Uncharacterized protein. (309 aa) | ||||
Doc2a | C2 domain-containing protein. (62 aa) | ||||
dnm1l | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa) | ||||
cdx1-2 | Tyrosinase_Cu-bd domain-containing protein. (299 aa) | ||||
tyr | Uncharacterized protein. (531 aa) | ||||
ap2m1 | AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP50 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositide- containing lipids (By similarity). (437 aa) | ||||
rab38 | Glutathione peroxidase 1. (212 aa) | ||||
ENSXETP00000022077 | Uncharacterized protein. (483 aa) | ||||
slc17a6 | LDL receptor related protein associated protein 1. (583 aa) | ||||
NECAP1 | NECAP endocytosis associated 1. (252 aa) | ||||
dbh | Ectodermal-neural cortex (with BTB-like domain), gene 2. (615 aa) | ||||
cep135 | Centrosomal protein 135kDa. (340 aa) | ||||
slc18a3 | MFS domain-containing protein. (524 aa) | ||||
epn3 | Acyl-CoA dehydrogenase short chain. (603 aa) | ||||
ap2s1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa) | ||||
lamp5 | Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain. (276 aa) | ||||
copg1 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (874 aa) | ||||
cgref1 | Uncharacterized protein. (253 aa) | ||||
sec24a | Elastin microfibril interfacer 1. (1122 aa) | ||||
rab3b | Rab3b protein. (217 aa) | ||||
cdkn2aipnl | Lysophosphatidylcholine acyltransferase 1. (93 aa) | ||||
exph5 | Fibrillin 3. (1692 aa) | ||||
or9q2 | Uncharacterized protein. (839 aa) | ||||
TEPSIN | TEPSIN adaptor related protein complex 4 accessory protein. (563 aa) | ||||
cyb561 | Laminin subunit alpha 5. (246 aa) | ||||
arcn1 | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (545 aa) | ||||
slc39a14 | Zinc transporter ZIP14; Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron. (470 aa) | ||||
atp6v1a | Glypican 5. (596 aa) | ||||
crp | Pentaxin. (234 aa) | ||||
wdr86 | Failed axon connections homolog. (415 aa) | ||||
syt4 | Uncharacterized protein. (424 aa) | ||||
sar1b | MGC108053 protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) | ||||
tmem163 | B-TFIID TATA-box binding protein associated factor 1. (281 aa) | ||||
STXBP5L | Syntaxin binding protein 5 like. (1236 aa) | ||||
pphln1 | Zinc finger DHHC-type containing 8. (346 aa) | ||||
PSPC1 | Paraspeckle component 1. (517 aa) | ||||
ap3b2 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1106 aa) | ||||
AP1G1 | AP-1 complex subunit gamma. (815 aa) | ||||
gpr107-3 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (240 aa) | ||||
clint1-2 | CDGSH iron sulfur domain 1. (1037 aa) | ||||
olah | Nuclear receptor subfamily 2 group C member 2. (254 aa) | ||||
trim72 | Tripartite motif-containing protein 72; Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)- depen [...] (477 aa) | ||||
copz1 | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (177 aa) | ||||
pip4p1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (327 aa) | ||||
slc12a6 | Interleukin 4 induced 1. (1159 aa) | ||||
dennd1a | Tec protein tyrosine kinase. (904 aa) | ||||
copb2 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (920 aa) | ||||
vti1b | t-SNARE coiled-coil homology domain-containing protein. (221 aa) | ||||
SYNRG | Synergin gamma. (1129 aa) | ||||
entpd7 | Ectonucleoside triphosphate diphosphohydrolase 7; Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP (By similarity). (617 aa) | ||||
ap1m1 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (455 aa) | ||||
tmem184a | SEC14-like protein 5. (434 aa) | ||||
LOC100486739 | Pentaxin. (230 aa) | ||||
ap1m2 | AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (426 aa) | ||||
prl.2-2 | Uncharacterized protein. (340 aa) | ||||
ap2b1 | AP complex subunit beta. (970 aa) | ||||
AFTPH | Clathrin_bdg domain-containing protein. (868 aa) | ||||
LOC100144286 | LOC100144286 protein. (362 aa) | ||||
ap1g2 | AP-1 complex subunit gamma. (787 aa) | ||||
phactr2 | Phosphatase and actin regulator. (582 aa) | ||||
neu3 | Treacher Collins-Franceschetti syndrome 1. (397 aa) | ||||
pld3 | 5'-3' exonuclease PLD3; 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (By similarity). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity). May be important in myotube formation. Plays a role in lysosomal homeostasis. Involved in the regulation of endosomal protein sorting (By similarity). (503 aa) | ||||
stx10 | t-SNARE coiled-coil homology domain-containing protein. (252 aa) | ||||
sec31a | Pregnancy-specific beta-1-glycoprotein 3. (1261 aa) | ||||
epn1 | UV-stimulated scaffold protein A. (652 aa) | ||||
slc45a2 | Uncharacterized protein. (586 aa) | ||||
LOC100496061 | Uncharacterized protein. (210 aa) | ||||
cd276 | Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein. (88 aa) | ||||
SYT11 | C2 domain-containing protein. (124 aa) | ||||
slc45a1 | Nuclear receptor subfamily 0 group B member 1. (747 aa) | ||||
ENSXETP00000011813 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (180 aa) | ||||
syn2 | Oxysterol binding protein like 1A. (877 aa) | ||||
rab9b | RAB9B, member RAS oncogene family. (201 aa) | ||||
DAB2 | DAB adaptor protein 2. (820 aa) | ||||
higd1a-2 | Solute carrier family 34 member 2. (1184 aa) | ||||
rab26 | Uncharacterized protein. (249 aa) | ||||
anxa3 | Annexin. (331 aa) | ||||
SEC31B | SEC31 homolog B, COPII coat complex component. (1211 aa) | ||||
vps45 | Vacuolar protein sorting 45A; Belongs to the STXBP/unc-18/SEC1 family. (570 aa) | ||||
snx9 | Sorting nexin. (585 aa) | ||||
LOC100494227 | Pentaxin. (232 aa) | ||||
tubgcp2 | Pentaxin. (231 aa) | ||||
ABCA3 | ATP binding cassette subfamily A member 3. (1704 aa) | ||||
sv2a | Plastin 1. (729 aa) | ||||
tcp11l2-2 | Uncharacterized protein. (987 aa) | ||||
zfyve28 | Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. (954 aa) | ||||
sec23b | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa) | ||||
GABRA2 | Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (499 aa) | ||||
sv2c | Trace amine-associated receptor 1. (725 aa) | ||||
EMILIN2 | Elastin microfibril interfacer 2. (1166 aa) | ||||
ap2a1 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (959 aa) | ||||
rab35 | RAB35, member RAS oncogene family. (201 aa) | ||||
clba1 | Family with sequence similarity 114 member A1. (296 aa) | ||||
znf609 | Zinc finger protein 609. (156 aa) | ||||
ocrl | Hairy and enhancer of split 5, gene 2. (909 aa) | ||||
epn2 | ENTH domain-containing protein. (586 aa) | ||||
syt1 | E2F transcription factor 4. (425 aa) | ||||
kcp | PHD finger protein 6. (2331 aa) | ||||
ccdc136 | Uncharacterized protein. (416 aa) | ||||
pip4p2 | Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (276 aa) | ||||
copg2 | Coatomer subunit gamma-2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). (883 aa) | ||||
SLC35B4 | Solute carrier family 35 member B4. (331 aa) | ||||
slc45a4 | E3 ubiquitin-protein ligase ZNRF3. (784 aa) | ||||
INPP5B | Inositol polyphosphate-5-phosphatase B. (891 aa) | ||||
ZFAND1 | Zinc finger AN1-type containing 1. (268 aa) | ||||
tuba3e | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (462 aa) | ||||
tuba4 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) | ||||
pef1 | Electron transfer flavoprotein dehydrogenase. (284 aa) | ||||
KCNV2 | Potassium voltage-gated channel modifier subfamily V member 2. (562 aa) | ||||
sec23a | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa) | ||||
litaf | Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation. May also contribute to the regulation of gene expression in the nucleus. Binds DNA (in vitro) and may play a synergistic role in the nucleus in regulating the expression of numerous cytokines. (188 aa) | ||||
npas3 | Uncharacterized protein. (949 aa) | ||||
CLEC16A | C-type lectin domain containing 16A. (1043 aa) | ||||
DNAJC5B | DnaJ heat shock protein family (Hsp40) member C5 beta. (196 aa) | ||||
scg3 | Secretogranin-3; Member of the granin protein family that regulates the biogenesis of secretory granules (By similarity). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (By similarity). May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (By similarity). (461 aa) | ||||
atp6v0b | Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (216 aa) | ||||
abcb6 | ATP-binding cassette sub-family B member 6, mitochondrial; Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis (By similarity). (852 aa) | ||||
RAB3C | RAB3C, member RAS oncogene family. (227 aa) | ||||
sv2b | Desmoplakin. (711 aa) | ||||
mreg | Melanoregulin; Probably functions as cargo-recognition protein that couples cytoplasmic vesicles to the transport machinery. Contributes to retrograde melanosome transport from the cell periphery to the center. Overexpression causes accumulation of late endosomes and/or lysosomes at the microtubule organising center (MTOC) at the center of the cell. Probably binds cholesterol and requires the presence of cholesterol in membranes to function in microtubule-mediated retrograde organelle transport. Binds phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinosi [...] (270 aa) | ||||
ap4m1 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (446 aa) | ||||
COPZ2 | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (180 aa) | ||||
prr15l | Uncharacterized protein. (96 aa) | ||||
rab5a | RAB5A, member RAS oncogene family. (216 aa) | ||||
trarg1 | Trafficking regulator of GLUT4 1; Regulates insulin-mediated adipose tissue glucose uptake and transport by modulation of SLC2A4 recycling. Belongs to the CD225/Dispanin family. (179 aa) | ||||
SLC17A8 | Solute carrier family 17 member 8. (588 aa) | ||||
gad2 | Peptidoglycan recognition protein 1. (588 aa) | ||||
LOC101732697 | G protein-coupled receptor 158. (209 aa) | ||||
coro6 | Coronin; Belongs to the WD repeat coronin family. (471 aa) | ||||
tmtc2-2 | Transmembrane and tetratricopeptide repeat containing 2. (878 aa) | ||||
tyrp1 | Tyrosinase-related protein 1. (534 aa) | ||||
rab32 | Uncharacterized protein. (258 aa) | ||||
miga1 | Uncharacterized protein. (574 aa) | ||||
prrt1 | Sushi domain containing 2. (240 aa) | ||||
lamtor3-like | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). (124 aa) | ||||
chmp4b | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). (222 aa) | ||||
ENSXETP00000047030 | Uncharacterized protein. (337 aa) | ||||
wdr91 | WD repeat-containing protein 91; Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport; Belongs to the WD repeat WDR91 family. (751 aa) | ||||
scarb2 | Uncharacterized protein; Belongs to the CD36 family. (487 aa) | ||||
psap-2 | Prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy). (257 aa) | ||||
tgm2-2 | Transglutaminase 2. (2204 aa) | ||||
nampt | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (506 aa) | ||||
copa | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1240 aa) | ||||
LOC100492396 | Ribonuclease H2 subunit B. (240 aa) | ||||
chmp5 | Charged multivesicular body protein 5; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). (240 aa) | ||||
coro1c | Coronin; Belongs to the WD repeat coronin family. (751 aa) | ||||
gpr143 | G_PROTEIN_RECEP_F2_4 domain-containing protein. (414 aa) | ||||
syn3 | Uncharacterized protein. (570 aa) | ||||
pam | Uncharacterized protein. (985 aa) | ||||
RASSF9 | Ras association domain family member 9. (422 aa) | ||||
smc2-2 | Structural maintenance of chromosomes 2. (1957 aa) | ||||
rab3d | RAB3D, member RAS oncogene family. (216 aa) | ||||
lamtor2 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). (125 aa) | ||||
ap2a2 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (1010 aa) | ||||
sulf2 | Extracellular sulfatase. (875 aa) | ||||
tmem184b | Naked cuticle homolog 1. (425 aa) | ||||
stx6 | Regulator of G-protein signaling 10; Belongs to the syntaxin family. (264 aa) | ||||
vma21 | Vacuolar ATPase assembly integral membrane protein vma21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (104 aa) | ||||
SYTL4 | Synaptotagmin like 4. (692 aa) | ||||
LOC100036702 | Exonuclease domain-containing protein. (1053 aa) | ||||
bri3 | LOC100144285 protein. (134 aa) | ||||
chmp7 | Charged multivesicular body protein 7; ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway; Belongs to the SNF7 family. (469 aa) |