STRINGSTRING
SLC9A9 SLC9A9 ehd1 ehd1 rab11fip5 rab11fip5 atp13a4 atp13a4 washc1 washc1 atp13a5 atp13a5 slc9a7 slc9a7 rab11a rab11a ehd4 ehd4 relch relch neu3 neu3 mlc1 mlc1 LOC100494483 LOC100494483 LOC101730879 LOC101730879 abhd17b abhd17b tmem255a tmem255a lztr1 lztr1 vps50 vps50 ATP13A3 ATP13A3 vps51 vps51 lamp5 lamp5 ehd2 ehd2 atp11a atp11a cmtm6 cmtm6 ras-dva1 ras-dva1 atp13a-like atp13a-like gpr161 gpr161 nsg1 nsg1 LOC100489013 LOC100489013 scamp2 scamp2 LOC100495031 LOC100495031 pheta2 pheta2 ehd3 ehd3 rap2b rap2b zfyve27 zfyve27 clcn3 clcn3 scamp1 scamp1 INPPL1 INPPL1 Syt11 Syt11 ENSXETP00000034327 ENSXETP00000034327 abhd17a abhd17a rab11b.2 rab11b.2 rab11b.1 rab11b.1 vipas39 vipas39 avl9 avl9 LOC100494846 LOC100494846 ENSXETP00000041053 ENSXETP00000041053 LOC100496476 LOC100496476 micall1 micall1 LOC101733684 LOC101733684 LOC100497259 LOC100497259 ndrg1 ndrg1 gga3 gga3 micall2 micall2 rap2a rap2a stx8 stx8 tbc1d12 tbc1d12 rap2c rap2c abhd17c abhd17c cftr cftr dennd6a dennd6a grpel2-2 grpel2-2 spdef spdef
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (630 aa)
ehd1Nuclear factor, erythroid 2 like 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
rab11fip5Uncharacterized protein. (1534 aa)
atp13a4Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1203 aa)
washc1WASH complex subunit 1; Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Its assembly in the WASH core complex seems to inhibit its NPF activity and is required for its membrane targeting; Belongs to the WASH1 family. (472 aa)
atp13a5Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1194 aa)
slc9a7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (710 aa)
rab11aRAB11A, member RAS oncogene family. (216 aa)
ehd4Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (537 aa)
relchRAB11-binding protein RELCH homolog; May regulate intracellular cholesterol transport. (1220 aa)
neu3Treacher Collins-Franceschetti syndrome 1. (397 aa)
mlc1Megalencephalic leukoencephalopathy with subcortical cysts 1 gene product. (377 aa)
LOC100494483Endoribonuclease LACTB2. (256 aa)
LOC101730879PhoLip_ATPase_N domain-containing protein. (175 aa)
abhd17bAlpha/beta hydrolase domain-containing protein 17B; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins; Belongs to the AB hydrolase superfamily. ABHD17 family. (288 aa)
tmem255aChondroitin sulfate N-acetylgalactosaminyltransferase 2. (321 aa)
lztr1Uncharacterized protein. (804 aa)
vps50Ccdc132 protein. (964 aa)
ATP13A3Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1247 aa)
vps51Vacuolar protein sorting-associated protein 51 homolog; Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling. (782 aa)
lamp5Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain. (276 aa)
ehd2MGC107790 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (538 aa)
atp11aPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1194 aa)
cmtm6Uncharacterized protein. (172 aa)
ras-dva1Ras-related protein ras-dva. (211 aa)
atp13a-likeCation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1139 aa)
gpr161G-protein coupled receptor 161; Key negative regulator of Shh signaling during neural tube development. Recruited to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of gli3 into gli3r and repress the Shh signaling. In presence of shh, it is removed from primary cilia, preventing its activity and allowing activation of the Shh signaling (By similarity); Belongs to the G-protein coupled receptor 1 family. (521 aa)
nsg1DDB1- and CUL4-associated factor 13. (185 aa)
LOC100489013Mitotic-spindle organizing protein 2B. (835 aa)
scamp2Secretory carrier-associated membrane protein. (330 aa)
LOC100495031Uncharacterized protein. (779 aa)
pheta2PH domain containing endocytic trafficking adaptor 2. (249 aa)
ehd3Dual specificity tyrosine phosphorylation regulated kinase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (551 aa)
rap2bRAP2B, member of RAS oncogene family. (182 aa)
zfyve27Cell division cycle associated 4. (445 aa)
clcn3Chloride channel protein. (867 aa)
scamp1Secretory carrier-associated membrane protein. (355 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (925 aa)
Syt11Synaptotagmin 11. (295 aa)
ENSXETP00000034327PH domain-containing protein. (171 aa)
abhd17aHypothetical LOC496639. (305 aa)
rab11b.2Human immunodeficiency virus type I enhancer binding protein 3. (218 aa)
rab11b.1Leucine rich repeat containing 8 VRAC subunit A. (221 aa)
vipas39Vps16_C domain-containing protein. (463 aa)
avl9UDENN domain-containing protein. (641 aa)
LOC100494846Golgi membrane protein 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1102 aa)
ENSXETP00000041053Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1096 aa)
LOC100496476Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1205 aa)
micall1Tetratricopeptide repeat domain 14. (775 aa)
LOC101733684Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1175 aa)
LOC100497259Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1171 aa)
ndrg1Protein NDRG1; May be involved in pronephros development, after specification of the pronephros. (399 aa)
gga3Uncharacterized protein. (706 aa)
micall2Discs large homolog 5. (1023 aa)
rap2aRAP2A, member of RAS oncogene family. (183 aa)
stx8t-SNARE coiled-coil homology domain-containing protein. (272 aa)
tbc1d12TBC1 domain family member 12; May act as a GTPase-activating protein for Rab family protein(s). (684 aa)
rap2cRAP2C, member of RAS oncogene family. (183 aa)
abhd17cAlpha/beta hydrolase domain-containing protein 17C; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins; Belongs to the AB hydrolase superfamily. ABHD17 family. (310 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1493 aa)
dennd6aBMP binding endothelial regulator. (556 aa)
grpel2-2GrpE like 2, mitochondrial. (254 aa)
spdefSAM pointed domain containing ets transcription factor. (317 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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