STRINGSTRING
chrne chrne sorcs3 sorcs3 lrfn4 lrfn4 CNIH3 CNIH3 shank2 shank2 camk2n2 camk2n2 optn optn cnmd cnmd Pcdh8.2 Pcdh8.2 PCDH17 PCDH17 musk musk drd5 drd5 ophn1 ophn1 nap1l4 nap1l4 rab11a rab11a NETO1 NETO1 vasn vasn fxyd6 fxyd6 stag1 stag1 PPP1R9A PPP1R9A lrrc4c lrrc4c nos3 nos3 kctd1 kctd1 trpv4l.3 trpv4l.3 SLITRK5 SLITRK5 neto2 neto2 homer3 homer3 ppp1r9al ppp1r9al lrrc4b lrrc4b IL1RAPL1 IL1RAPL1 znf180-2 znf180-2 dock10 dock10 grip1 grip1 CADM1 CADM1 homer1 homer1 gabrd gabrd chrna1.2 chrna1.2 chrna1 chrna1 LRRTM4 LRRTM4 abhd17b abhd17b trpv3 trpv3 LZTS3 LZTS3 pin1 pin1 tmem255a tmem255a fmr1 fmr1 nsun2 nsun2 kpna2 kpna2 PCDH19 PCDH19 cnih2 cnih2 clta clta kpna7 kpna7 gatad1 gatad1 lzts1 lzts1 LRRC4C LRRC4C TANC2 TANC2 dlgap1 dlgap1 CHRNB3 CHRNB3 clstn3 clstn3 camk2g camk2g mpp6 mpp6 CLSTN2 CLSTN2 ttyh2 ttyh2 NOS1 NOS1 HLTF HLTF lrfn2 lrfn2 lin7b lin7b ampd3 ampd3 chrnb2 chrnb2 pcdh8 pcdh8 cacng8 cacng8 ptpn21 ptpn21 nr1d1 nr1d1 lin7c lin7c fkbp11 fkbp11 ppp1r9b ppp1r9b mpp2 mpp2 dnaja3 dnaja3 trpv4l.4 trpv4l.4 cnppd1-2 cnppd1-2 crtc1 crtc1 synpo synpo pld2 pld2 SGPL1 SGPL1 trpv4l.2 trpv4l.2 GRIP2 GRIP2 trpv4 trpv4 rapsn rapsn gphn gphn lrrc4 lrrc4 fxr1 fxr1 Dock10 Dock10 nsmf nsmf grasp grasp mgc69473 mgc69473 otop1-2 otop1-2 adam22 adam22 kcnd1 kcnd1 Syt11 Syt11 ACE2 ACE2 trpv1 trpv1 abhd17a abhd17a ADAMTS10 ADAMTS10 LOC100494266 LOC100494266 LOC101731452 LOC101731452 arhgap42 arhgap42 rab11b.2 rab11b.2 rab11b.1 rab11b.1 plppr3 plppr3 lrrtm1 lrrtm1 GRIN3B GRIN3B LOC100488097 LOC100488097 pick1-2 pick1-2 dlgap2 dlgap2 SHANK3 SHANK3 pcdh8l pcdh8l chrna5 chrna5 nptx2 nptx2 cript cript chad chad xylt2 xylt2 bambi bambi ENSXETP00000043179 ENSXETP00000043179 ENSXETP00000043197 ENSXETP00000043197 DRD1 DRD1 il1rapl2 il1rapl2 mppe1 mppe1 gper1 gper1 palmd palmd chrnb4 chrnb4 chrnd chrnd GRID2IP GRID2IP chrng chrng slitrk3 slitrk3 RGS7BP RGS7BP DRD4 DRD4 FGD1 FGD1 hspa8 hspa8 prrt1 prrt1 PLPPR4 PLPPR4 drd1c drd1c cltb cltb NEFL NEFL dlgap3 dlgap3 abhd17c abhd17c wnk3 wnk3 LRFN5 LRFN5 CTTNBP2 CTTNBP2 KCND2 KCND2 rab5a rab5a abr abr cntn2 cntn2 gdf5-2 gdf5-2 ALS2 ALS2 nrp2 nrp2 shisa9 shisa9 nptn nptn insyn1 insyn1 ENSXETP00000053770 ENSXETP00000053770 TANC1 TANC1 SHC4 SHC4 homer2 homer2 INSYN2A INSYN2A nos2 nos2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chrneTubulin alpha 1 like. (465 aa)
sorcs3Semaphorin 4C. (998 aa)
lrfn4Uncharacterized protein. (722 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (152 aa)
shank2Uncharacterized protein. (1829 aa)
camk2n2Calcium/calmodulin-dependent protein kinase II inhibitor 2; Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2 (By similarity). Belongs to the CAMK2N family. (79 aa)
optnFatty acid binding protein 6, ileal. (553 aa)
cnmdLect1 protein. (337 aa)
Pcdh8.2Uncharacterized protein. (980 aa)
PCDH17Protocadherin 17. (1151 aa)
muskNIPA magnesium transporter 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (935 aa)
drd5Cytotoxic and regulatory T cell molecule; Belongs to the G-protein coupled receptor 1 family. (455 aa)
ophn1Fas associated via death domain. (792 aa)
nap1l4Nucleosome assembly protein 1like 4. (321 aa)
rab11aRAB11A, member RAS oncogene family. (216 aa)
NETO1Neuropilin and tolloid like 1. (529 aa)
vasnVasorin; May act as an inhibitor of TGF-beta signaling. (673 aa)
fxyd6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (94 aa)
stag1SCD domain-containing protein. (1265 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1156 aa)
lrrc4cUncharacterized protein. (264 aa)
nos3Nitric oxide synthase; Produces nitric oxide (NO). (1113 aa)
kctd1Potassium channel tetramerization domain containing 1. (302 aa)
trpv4l.3ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (637 aa)
SLITRK5SLIT and NTRK like family member 5. (881 aa)
neto2Uncharacterized protein. (525 aa)
homer3Rh-associated glycoprotein. (359 aa)
ppp1r9alUncharacterized protein. (1337 aa)
lrrc4bLOC100124949 protein. (641 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (686 aa)
znf180-2Zinc finger protein 180. (153 aa)
dock10DHR-2 domain-containing protein; Belongs to the DOCK family. (433 aa)
grip1Nuclear respiratory factor 1. (1130 aa)
CADM1Cell adhesion molecule 1. (457 aa)
homer1Prolactin-releasing peptide receptor-like. (394 aa)
gabrdG protein-coupled receptor 137B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (428 aa)
chrna1.2Uncharacterized protein. (477 aa)
chrna1AT-rich interaction domain 2. (471 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (622 aa)
abhd17bAlpha/beta hydrolase domain-containing protein 17B; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins; Belongs to the AB hydrolase superfamily. ABHD17 family. (288 aa)
trpv3Transient receptor potential vanilloid 3; Belongs to the transient receptor (TC 1.A.4) family. (773 aa)
LZTS3Leucine zipper tumor suppressor family member 3. (654 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (159 aa)
tmem255aChondroitin sulfate N-acetylgalactosaminyltransferase 2. (321 aa)
fmr1Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C). ECO:0000250|UniProtKB:P51113, ECO:0000250|UniProtKB:Q06787. (590 aa)
nsun2RNA cytosine-C(5)-methyltransferase NSUN2; RNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Involved in various processes, such as epidermal stem cell differentiation, testis differentiation and maternal to zygotic transition during early development: acts by increasing protein synthesis; cytosine C(5)-methylation promoting tRNA stability and preventing mRNA decay. Methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) p [...] (798 aa)
kpna2Importin subunit alpha; Belongs to the importin alpha family. (528 aa)
PCDH19Protocadherin 19. (1101 aa)
cnih2Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs); Belongs to the cornichon family. (162 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (233 aa)
kpna7Importin subunit alpha; Belongs to the importin alpha family. (523 aa)
gatad1Uncharacterized LOC100127267. (268 aa)
lzts1Lzts1 protein. (499 aa)
LRRC4CLeucine rich repeat containing 4C. (639 aa)
TANC2Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2. (2064 aa)
dlgap1UTP18 small subunit processome component. (980 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (447 aa)
clstn3Glycogen synthase kinase 3 alpha. (965 aa)
camk2gProtein kinase domain-containing protein. (643 aa)
mpp6ADAMTS like 3; Belongs to the MAGUK family. (584 aa)
CLSTN2Calsyntenin 2. (921 aa)
ttyh2Protein tweety homolog 2; Probable large-conductance Ca(2+)-activated chloride channel. Belongs to the tweety family. (534 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1420 aa)
HLTFHelicase like transcription factor. (991 aa)
lrfn2RRN3 homolog, RNA polymerase I transcription factor. (765 aa)
lin7bProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
ampd3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (782 aa)
chrnb2Uncharacterized protein. (499 aa)
pcdh8Protocadherin 8. (1002 aa)
cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (353 aa)
ptpn21Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1182 aa)
nr1d1Heparan sulfate 6-O-sulfotransferase 3. (529 aa)
lin7cProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
fkbp11FKBP prolyl isomerase 11. (329 aa)
ppp1r9bFrizzled related protein 2. (791 aa)
mpp2Activating transcription factor 5, gene 2; Belongs to the MAGUK family. (559 aa)
dnaja3Uncharacterized protein. (506 aa)
trpv4l.4ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (770 aa)
cnppd1-2Caspase 2. (84 aa)
crtc1Josephin domain containing 1. (623 aa)
synpoTransmembrane protein 147. (949 aa)
pld2Phospholipase. (985 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (573 aa)
trpv4l.2Semaphorin 4D; Belongs to the transient receptor (TC 1.A.4) family. (776 aa)
GRIP2Glutamate receptor interacting protein 2. (1122 aa)
trpv4Forkhead box protein D3; Belongs to the transient receptor (TC 1.A.4) family. (868 aa)
rapsnMgc107969 protein. (414 aa)
gphnGlucocorticoid modulatory element binding protein 2. (970 aa)
lrrc4Ig-like domain-containing protein. (641 aa)
fxr1Fragile X mental retardation syndrome-related protein 1 homolog; RNA-binding protein. Binds poly(G) and poly(U) but not poly(A) or poly(C). Regulates somite formation, probably by regulating gene expression (By similarity). (674 aa)
Dock10PH domain-containing protein. (498 aa)
nsmfProtein KIBRA. (503 aa)
graspPDZ domain-containing protein. (352 aa)
mgc69473Ion_trans domain-containing protein. (509 aa)
otop1-2Otopetrin 1. (526 aa)
adam22Uncharacterized protein. (918 aa)
kcnd1BTB domain-containing protein; Belongs to the potassium channel family. (631 aa)
Syt11Synaptotagmin 11. (295 aa)
ACE2Angiotensin-converting enzyme. (862 aa)
trpv1ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (840 aa)
abhd17aHypothetical LOC496639. (305 aa)
ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10. (1085 aa)
LOC100494266Interphotoreceptor matrix proteoglycan 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (484 aa)
LOC101731452EGF-like-domain, multiple 6; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (415 aa)
arhgap42Uncharacterized protein. (898 aa)
rab11b.2Human immunodeficiency virus type I enhancer binding protein 3. (218 aa)
rab11b.1Leucine rich repeat containing 8 VRAC subunit A. (221 aa)
plppr3LOC100145312 protein. (704 aa)
lrrtm1Cerebellar degeneration-related protein 2-like. (521 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1035 aa)
LOC100488097Fibronectin type-III domain-containing protein. (660 aa)
pick1-2Uncharacterized protein. (421 aa)
dlgap2Vacuolar protein sorting 4 homolog A. (973 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1850 aa)
pcdh8lCrumbs 2, cell polarity complex component. (977 aa)
chrna5RNA polymerase II associated protein 1. (476 aa)
nptx2Nptx2 protein. (439 aa)
criptUncharacterized protein. (102 aa)
chadUncharacterized protein. (360 aa)
xylt2Uncharacterized protein. (837 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
ENSXETP00000043179Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (306 aa)
ENSXETP00000043197Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (369 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (442 aa)
il1rapl2Interleukin 1 receptor accessory protein-like 2. (686 aa)
mppe1Metallophosphoesterase 1. (494 aa)
gper1Tripartite motif containing 55; Belongs to the G-protein coupled receptor 1 family. (361 aa)
palmdInsulin like growth factor 2 receptor. (542 aa)
chrnb4Ubiquitin carboxyl-terminal hydrolase 16. (497 aa)
chrndUncharacterized protein. (556 aa)
GRID2IPGrid2 interacting protein. (1159 aa)
chrngExosome component 7. (511 aa)
slitrk3Chitinase domain-containing protein 1. (885 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (271 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (414 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (923 aa)
hspa8WD repeat-containing protein 26; Belongs to the heat shock protein 70 family. (654 aa)
prrt1Sushi domain containing 2. (240 aa)
PLPPR4Phospholipid phosphatase related 4. (770 aa)
drd1cSmall nuclear ribonucleoprotein polypeptide A; Belongs to the G-protein coupled receptor 1 family. (465 aa)
cltbClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (223 aa)
NEFLNeurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. (554 aa)
dlgap3Uncharacterized protein. (999 aa)
abhd17cAlpha/beta hydrolase domain-containing protein 17C; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins; Belongs to the AB hydrolase superfamily. ABHD17 family. (310 aa)
wnk3Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (775 aa)
CTTNBP2Cortactin binding protein 2. (1706 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (627 aa)
rab5aRAB5A, member RAS oncogene family. (216 aa)
abrActive breakpoint cluster region-related protein; Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GD [...] (1019 aa)
cntn2Polymerase (RNA) II subunit I. (1013 aa)
gdf5-2Growth differentiation factor 5. (1420 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1640 aa)
nrp2Neuropilin; Belongs to the neuropilin family. (934 aa)
shisa9Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity). (390 aa)
nptnUncharacterized protein. (407 aa)
insyn1Uncharacterized protein. (247 aa)
ENSXETP00000053770Uncharacterized protein. (120 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1828 aa)
SHC4SHC adaptor protein 4. (500 aa)
homer2Lactate dehydrogenase B. (382 aa)
INSYN2AInhibitory synaptic factor 2A. (478 aa)
nos2Nitric oxide synthase; Produces nitric oxide (NO). (1172 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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