STRINGSTRING
h2bc14 h2bc14 h3c13 h3c13 LOC108648864 LOC108648864 ENSXETP00000002330 ENSXETP00000002330 h2ac21 h2ac21 h2bc21 h2bc21 h2ac1 h2ac1 h3-3b h3-3b h2az2 h2az2 LOC100495625 LOC100495625 ttc39a-2 ttc39a-2 h2afx.2 h2afx.2 h2az1 h2az1 macroh2a2 macroh2a2 LOC100492813 LOC100492813 h2bc12 h2bc12 cenpa cenpa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
h2bc14Histone H2B; Belongs to the histone H2B family. (126 aa)
h3c13Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
LOC108648864Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSXETP00000002330Histone H3; Belongs to the histone H3 family. (136 aa)
h2ac21Histone H2A; Belongs to the histone H2A family. (130 aa)
h2bc21Histone H2B; Belongs to the histone H2B family. (126 aa)
h2ac1Histone H2A; Belongs to the histone H2A family. (138 aa)
h3-3bHistone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
h2az2Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] (128 aa)
LOC100495625Histone H2A; Belongs to the histone H2A family. (130 aa)
ttc39a-2Histone H2B; Belongs to the histone H2B family. (126 aa)
h2afx.2Histone H2A; Belongs to the histone H2A family. (143 aa)
h2az1Histone H2A.Z-like; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be required at gastrulation for correct mesoderm formation (By similarity). (129 aa)
macroh2a2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
LOC100492813Histone H2A; Belongs to the histone H2A family. (130 aa)
h2bc12Histone H2B; Belongs to the histone H2B family. (126 aa)
cenpaHistone H3-like centromeric protein A; Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Required [...] (150 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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