STRINGSTRING
hcn4 hcn4 NALCN NALCN tpcn1 tpcn1 CACNA1A CACNA1A tpcn2 tpcn2 trpv4l.3 trpv4l.3 TRPC1 TRPC1 hcn2 hcn2 cat1 cat1 trpv5 trpv5 trpv3 trpv3 trpm3 trpm3 scn5a scn5a CACNA1I CACNA1I cacna1h cacna1h Cacna1b Cacna1b trpm4 trpm4 TRPC5 TRPC5 CACNA1D CACNA1D trpv2 trpv2 TRPM6 TRPM6 trpc4 trpc4 LOC100495031 LOC100495031 trpv4l.4 trpv4l.4 tpte2 tpte2 trpv4l.2 trpv4l.2 cnga2 cnga2 cnga4 cnga4 trpv4 trpv4 ENSXETP00000032157 ENSXETP00000032157 mgc69473 mgc69473 otop1-2 otop1-2 trpv1 trpv1 pkd1l2 pkd1l2 pkd2 pkd2 hvcn1 hvcn1 HCN1 HCN1 LOC100489231 LOC100489231 amacr-2 amacr-2 cacna1e cacna1e cacna1g cacna1g SCN4A SCN4A cacna1f cacna1f LOC101734375 LOC101734375 tmem266 tmem266 rbm19-2 rbm19-2 itpr1 itpr1 cacna1s cacna1s ccdc38 ccdc38 RYR1 RYR1 cnga3 cnga3 CACNA1C CACNA1C PKD2L1 PKD2L1 scn1a scn1a trpm8b trpm8b trpm8 trpm8 scn2a scn2a LOC101732351 LOC101732351 itpr3 itpr3 ryr3 ryr3 scn3a scn3a TRPM1 TRPM1 LOC100495521 LOC100495521 trpa1 trpa1 trpm7 trpm7 LOC100497855 LOC100497855
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hcn4Cadherin 19, type 2. (1216 aa)
NALCNSodium leak channel, non-selective. (1753 aa)
tpcn1DDB1 and CUL4 associated factor 15. (750 aa)
CACNA1ACalcium voltage-gated channel subunit alpha1 A. (2345 aa)
tpcn2Hook microtubule-tethering protein 1. (770 aa)
trpv4l.3ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (637 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (896 aa)
hcn2Limbic system associated membrane protein. (927 aa)
cat1TRAF family member associated NFKB activator; Belongs to the transient receptor (TC 1.A.4) family. (587 aa)
trpv5RAB7A, member RAS oncogene family; Belongs to the transient receptor (TC 1.A.4) family. (645 aa)
trpv3Transient receptor potential vanilloid 3; Belongs to the transient receptor (TC 1.A.4) family. (773 aa)
trpm3Aldehyde dehydrogenase 3 family member A2. (1710 aa)
scn5aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2026 aa)
CACNA1ICalcium voltage-gated channel subunit alpha1 I. (2133 aa)
cacna1hVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2347 aa)
Cacna1bIon_trans domain-containing protein. (218 aa)
trpm4SHC (Src homology 2 domain containing) transforming protein 2. (1206 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (961 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1690 aa)
trpv2Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; Belongs to the transient receptor (TC 1.A.4) family. (754 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2001 aa)
trpc4Histidine triad nucleotide binding protein 1; Belongs to the transient receptor (TC 1.A.4) family. (965 aa)
LOC100495031Uncharacterized protein. (779 aa)
trpv4l.4ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (770 aa)
tpte2Uncharacterized protein. (511 aa)
trpv4l.2Semaphorin 4D; Belongs to the transient receptor (TC 1.A.4) family. (776 aa)
cnga2Omega-amidase NIT2. (675 aa)
cnga4Pleckstrin homology domain interacting protein. (573 aa)
trpv4Forkhead box protein D3; Belongs to the transient receptor (TC 1.A.4) family. (868 aa)
ENSXETP00000032157Ion_trans domain-containing protein. (263 aa)
mgc69473Ion_trans domain-containing protein. (509 aa)
otop1-2Otopetrin 1. (526 aa)
trpv1ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (840 aa)
pkd1l2Uncharacterized protein. (2206 aa)
pkd2Ubiquitin carboxyl-terminal hydrolase 33. (951 aa)
hvcn1Voltage-gated hydrogen channel 1; Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient (By similarity). (230 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (820 aa)
LOC100489231Isochorismatase domain-containing protein 2. (1702 aa)
amacr-2Alpha-methylacyl-CoA racemase. (638 aa)
cacna1eVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2153 aa)
cacna1gAcyl-CoA synthetase long chain family member 1 protein. (2098 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1845 aa)
cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1825 aa)
LOC101734375TUB like protein 2; Belongs to the transient receptor (TC 1.A.4) family. (624 aa)
tmem266MCF.2 cell line derived transforming sequence-like 2. (461 aa)
rbm19-2RNA binding motif protein 19; Belongs to the transient receptor (TC 1.A.4) family. (602 aa)
itpr1Complement component 1, q subcomponent binding protein. (2614 aa)
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1660 aa)
ccdc38Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
RYR1Ryanodine receptor 1. (4991 aa)
cnga3Nuclear transcription factor Y subunit beta. (735 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2150 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (684 aa)
scn1aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2027 aa)
trpm8bCoiled-coil domain containing 125. (1090 aa)
trpm8Transient receptor potential cation channel subfamily M member 8. (1141 aa)
scn2aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1969 aa)
LOC101732351Uncharacterized protein. (294 aa)
itpr3Inositol (1,4,5) trisphosphate receptor type 3. (2673 aa)
ryr3Zinc finger MYM-type containing 2. (4848 aa)
scn3aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1634 aa)
LOC100495521Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1042 aa)
trpa1Transient receptor potential ankyrin 1; Belongs to the transient receptor (TC 1.A.4) family. (1144 aa)
trpm7Tsukushin. (1874 aa)
LOC100497855Transient receptor potential cation channel subfamily M member 7. (1736 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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