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h3c13-10 h3c13-10 cetn1 cetn1 CPEB4 CPEB4 h3c13-15 h3c13-15 mxd1 mxd1 h3c13-13 h3c13-13 CPEB2 CPEB2 cpeb1 cpeb1 lrch2-2 lrch2-2 h3c13-11 h3c13-11 h3c13 h3c13 actb actb ENSXETP00000002330 ENSXETP00000002330 h3c13-2 h3c13-2 CDH1 CDH1 h3c13-4 h3c13-4 h3c13-5 h3c13-5 cpeb3 cpeb3 h3-3b h3-3b gja7-2 gja7-2 h3c13-6 h3c13-6 h3c13-7 h3c13-7 h3c13-9 h3c13-9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
h3c13-10Histone H3. (136 aa)
cetn1Centrin, EF-hand protein, 2. (172 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (728 aa)
h3c13-15Histone H3. (136 aa)
mxd1Max dimerization protein 1; Transcriptional repressor. MAD binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MAD thus antagonizes MYC transcriptional activity by competing for MAX (By similarity). (155 aa)
h3c13-13Histone H3. (136 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (818 aa)
cpeb1Uncharacterized protein. (564 aa)
lrch2-2Histone H3; Belongs to the histone H3 family. (124 aa)
h3c13-11Histone H3. (136 aa)
h3c13Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
actbActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
ENSXETP00000002330Histone H3; Belongs to the histone H3 family. (136 aa)
h3c13-2Histone H3. (136 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (934 aa)
h3c13-4Histone H3. (136 aa)
h3c13-5Histone H3. (136 aa)
cpeb3Cytoplasmic polyadenylation element-binding protein 3; Sequence-specific RNA-binding protein which acts as a translational repressor in the basal unstimulated state but, following neuronal stimulation, acts as a translational activator (By similarity). Does not bind to the cytoplasmic polyadenylation element (CPE), a uridine-rich sequence element within the mRNA 3'-UTR, but binds to a U-rich loop within a stem-loop structure (By similarity). Required for the consolidation and maintenance of hippocampal-based long term memory (By similarity). Inhibits differentiation of intermediate mes [...] (603 aa)
h3-3bHistone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
gja7-2Histone H3; Belongs to the histone H3 family. (135 aa)
h3c13-6Histone H3. (136 aa)
h3c13-7Histone H3. (136 aa)
h3c13-9Histone H3. (136 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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