node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KIF1B | lamtor3-like | ENSXETP00000034740 | ENSXETP00000047176 | Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.414 |
KIF1B | rnf26 | ENSXETP00000034740 | ENSXETP00000000195 | Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Glycophorin C (Gerbich blood group). | 0.418 |
KIF1B | slc38a9 | ENSXETP00000034740 | ENSXETP00000037759 | Kinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.440 |
LOC100496215 | slc38a9 | ENSXETP00000027186 | ENSXETP00000037759 | Amino acid transporter. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.658 |
LOC100496635 | slc38a9 | ENSXETP00000026865 | ENSXETP00000037759 | Amino acid transporter. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.564 |
RABIF | lamtor1 | ENSXETP00000003959 | ENSXETP00000033697 | RAB interacting factor. | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). | 0.410 |
SLC1A1 | slc38a9 | ENSXETP00000053649 | ENSXETP00000037759 | Amino acid transporter. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.629 |
SLC1A2 | slc38a9 | ENSXETP00000036443 | ENSXETP00000037759 | Amino acid transporter. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.592 |
SLC1A7 | slc38a9 | ENSXETP00000039319 | ENSXETP00000037759 | Amino acid transporter. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.658 |
efna5 | lamtor1 | ENSXETP00000041206 | ENSXETP00000033697 | Ephrin-A5; Belongs to the ephrin family. | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). | 0.427 |
efna5 | lamtor3-like | ENSXETP00000041206 | ENSXETP00000047176 | Ephrin-A5; Belongs to the ephrin family. | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.410 |
efna5 | slc38a9 | ENSXETP00000041206 | ENSXETP00000037759 | Ephrin-A5; Belongs to the ephrin family. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.559 |
lamtor1 | RABIF | ENSXETP00000033697 | ENSXETP00000003959 | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). | RAB interacting factor. | 0.410 |
lamtor1 | efna5 | ENSXETP00000033697 | ENSXETP00000041206 | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). | Ephrin-A5; Belongs to the ephrin family. | 0.427 |
lamtor1 | lamtor2 | ENSXETP00000033697 | ENSXETP00000042434 | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.999 |
lamtor1 | lamtor3-like | ENSXETP00000033697 | ENSXETP00000047176 | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.999 |
lamtor1 | slc38a9 | ENSXETP00000033697 | ENSXETP00000037759 | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.998 |
lamtor2 | lamtor1 | ENSXETP00000042434 | ENSXETP00000033697 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ragulator complex protein LAMTOR1; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. May play a role in late endosomes/lysosomes biogenesis and regulate both the recycling of receptors through endosomes and the MAPK signaling pathway. May be involved in cholesterol homeostasis. May also play a role in RHOA activation (By similarity). | 0.999 |
lamtor2 | lamtor3-like | ENSXETP00000042434 | ENSXETP00000047176 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.999 |
lamtor2 | slc38a9 | ENSXETP00000042434 | ENSXETP00000037759 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.998 |