STRINGSTRING
CDH23 CDH23 PCDH15 PCDH15 dstn dstn sod2 sod2 gpx8 gpx8 gpx1 gpx1 cfl2 cfl2 cfl1 cfl1 gpx3 gpx3 gpx7 gpx7 MYO7A MYO7A actg1 actg1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDH23Cadherin related 23. (2204 aa)
PCDH15Protocadherin related 15. (1901 aa)
dstnSolute carrier family 1 member 2; Belongs to the actin-binding proteins ADF family. (153 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (226 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (143 aa)
cfl2Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity); Belongs to the actin-binding proteins ADF family. (167 aa)
cfl1Cofilin-1; May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Required for formation of the cleavage furrow during cytokinesis. (168 aa)
gpx3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (157 aa)
gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2231 aa)
actg1Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. (375 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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