STRINGSTRING
nos3 nos3 gpt gpt casp8 casp8 casp3.2 casp3.2 nos2 nos2 cyp2e1 cyp2e1 sod2 sod2 BCL2 BCL2 GPT2 GPT2 NOS1 NOS1 krt18.1 krt18.1 casp3.1 casp3.1 foxo3 foxo3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nos3Nitric oxide synthase; Produces nitric oxide (NO). (1113 aa)
gptAlanine aminotransferase 2; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. (784 aa)
casp8S-adenosylmethionine sensor upstream of mTORC1; Belongs to the peptidase C14A family. (504 aa)
casp3.2Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
nos2Nitric oxide synthase; Produces nitric oxide (NO). (1172 aa)
cyp2e1Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (226 aa)
BCL2BCL2 apoptosis regulator. (293 aa)
GPT2Alanine aminotransferase 2. (585 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1420 aa)
krt18.1Keratin, type I cytoskeletal 18; When phosphorylated, plays a role in filament reorganization. (429 aa)
casp3.1Uncharacterized protein; Belongs to the peptidase C14A family. (276 aa)
foxo3Foxo3 protein. (653 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
Server load: low (18%) [HD]