STRINGSTRING
ENSXETP00000027228 ENSXETP00000027228 MEGF11 MEGF11 LOC100494953 LOC100494953 f9 f9 PCSK5 PCSK5 pros1 pros1 atrnl1 atrnl1 THBS2 THBS2 thbd-2 thbd-2 npnt npnt STAB2 STAB2 hspg2 hspg2 proz proz F10 F10 f7 f7 CCBE1 CCBE1 LRP1 LRP1 dlc dlc VWA2 VWA2 LRP6 LRP6 nrg3 nrg3 susd1 susd1 lrp5 lrp5 mep1a mep1a scarf2 scarf2 nell1 nell1 pcsk6 pcsk6 MEGF8 MEGF8 jag1 jag1 ITGBL1 ITGBL1 pear1 pear1 tenm4 tenm4 notch2 notch2 LTBP3 LTBP3 lrp2 lrp2 JAG2 JAG2 BCAN BCAN Tenm3 Tenm3 ldlr ldlr nid2 nid2 pamr1 pamr1 hes6.1 hes6.1 FBLN7 FBLN7 FAT4 FAT4 wif1 wif1 egf egf vwce vwce fbn1 fbn1 VLDLR VLDLR hyal2 hyal2 DLL4 DLL4 NOTCH3 NOTCH3 notch1 notch1 adam23 adam23 hyal4 hyal4 adam9 adam9 kremen1-2 kremen1-2 mfge8 mfge8 malrd1 malrd1 cntnap4 cntnap4 tdgf1.1 tdgf1.1 matn1 matn1 cntnap5 cntnap5 FBN3 FBN3 TENM1 TENM1 GPR158 GPR158 adam28.2 adam28.2 adam7 adam7 NID1 NID1 THSD7A THSD7A Vwde Vwde TIE1 TIE1 reln reln notch4 notch4 tnc tnc egfl8 egfl8 ENSXETP00000047701 ENSXETP00000047701 SNED1 SNED1 ankfn1l ankfn1l itgb3 itgb3 lrp1b lrp1b NRXN3 NRXN3 tnr tnr egfl7 egfl7 TNN TNN megf10 megf10 FBN2 FBN2 hhip hhip scarf1 scarf1 plat plat ENSXETP00000043039 ENSXETP00000043039 gas6 gas6 LRP8 LRP8 proc proc LOC100145345 LOC100145345 pigo-2 pigo-2 TEK TEK oit3 oit3 UMOD UMOD ENSXETP00000041023 ENSXETP00000041023 ENSXETP00000040990 ENSXETP00000040990 ENSXETP00000040926 ENSXETP00000040926 dclk2 dclk2 agk agk ADGRL4 ADGRL4 celsr3 celsr3 astn2 astn2 megf6 megf6 EGFL6 EGFL6 ltbp1 ltbp1 FBLN2 FBLN2 nrxn2 nrxn2 mmrn1 mmrn1 pparg-2 pparg-2 HGFAC HGFAC c6.2 c6.2 nrg1 nrg1 ATRN ATRN astn1 astn1 NRXN1 NRXN1 cubn cubn tecta.1 tecta.1 f12 f12 sorl1 sorl1 EGFLAM EGFLAM celsr2 celsr2 slit2 slit2 thbs4 thbs4 THBS1 THBS1 LOC100493382 LOC100493382 adam22 adam22 habp2 habp2 VCAN VCAN crb2 crb2 thbs3 thbs3 muc4 muc4 slit1 slit1 edil3 edil3 BTC BTC LOC100485319 LOC100485319 umod.3 umod.3 c8b c8b LOC733728 LOC733728 ltbp4 ltbp4 galns-2 galns-2 CRELD2 CRELD2 cntnap1 cntnap1 HBEGF HBEGF cntnap2 cntnap2 LOC100493268 LOC100493268 comp comp adgre2 adgre2 MATN3 MATN3 MGC89178 MGC89178 ptgs2 ptgs2 matn2 matn2 vasn vasn FAT3 FAT3 SVEP1 SVEP1 thbd thbd dner dner cd93 cd93 nell2 nell2 scube2 scube2 BRINP3 BRINP3 fat1 fat1 tmem8a tmem8a SCUBE1 SCUBE1 nagpa nagpa tmeff1 tmeff1 matn4 matn4 prps1-2 prps1-2 areg areg ereg ereg epgn epgn mep1b mep1b NTNG2 NTNG2 slit3 slit3 NTNG1 NTNG1 fat2 fat2 dll1 dll1 rimkla-2 rimkla-2 tmeff2 tmeff2 CELSR1 CELSR1 TENM2 TENM2 lrp4 lrp4 adam19 adam19 NCAN NCAN adam11 adam11 tgfa tgfa agrn agrn cd248 cd248 crb1 crb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSXETP00000027228Uncharacterized protein. (294 aa)
MEGF11Multiple EGF like domains 11. (1085 aa)
LOC100494953Chaperonin containing TCP1 subunit 6A; Cadherins are calcium-dependent cell adhesion proteins. (2583 aa)
f9NADH:ubiquinone oxidoreductase core subunit V1. (463 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1786 aa)
pros1Uncharacterized protein. (673 aa)
atrnl1Citrate synthase, mitochondrial. (1356 aa)
THBS2Thrombospondin 2. (1215 aa)
thbd-2Leucine rich repeat containing 52. (520 aa)
npntCell division cycle 42. (650 aa)
STAB2Stabilin 2. (2366 aa)
hspg2SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (3447 aa)
prozUncharacterized protein; Belongs to the peptidase S1 family. (416 aa)
F10Coagulation factor X; Belongs to the peptidase S1 family. (282 aa)
f7Coagulation factor VII. (452 aa)
CCBE1Collagen and calcium binding EGF domains 1. (394 aa)
LRP1LDL receptor related protein 1. (4543 aa)
dlcDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa)
VWA2Von Willebrand factor A domain containing 2. (798 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1622 aa)
nrg3Dachshund family transcription factor 1. (658 aa)
susd1Uncharacterized protein. (923 aa)
lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
mep1aUncharacterized protein. (604 aa)
scarf2OTU deubiquitinase with linear linkage specificity like. (942 aa)
nell1IBA57, iron-sulfur cluster assembly. (787 aa)
pcsk6Ganglioside induced differentiation associated protein 1-like 1; Belongs to the peptidase S8 family. (932 aa)
MEGF8Multiple EGF like domains 8. (2730 aa)
jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ITGBL1Integrin subunit beta like 1. (488 aa)
pear1Uncharacterized protein. (1022 aa)
tenm4Uncharacterized protein. (2596 aa)
notch2FTO alpha-ketoglutarate dependent dioxygenase. (2455 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1154 aa)
lrp2Rab geranylgeranyltransferase subunit beta. (4662 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1133 aa)
BCANBrevican. (1148 aa)
Tenm3Teneurin transmembrane protein 3. (2803 aa)
ldlrPhosphatidylinositol glycan anchor biosynthesis class S. (938 aa)
nid2Uncharacterized protein. (1520 aa)
pamr1Inactive serine protease PAMR1; May play a role in regeneration of skeletal muscle. Belongs to the peptidase S1 family. (664 aa)
hes6.1Junctional adhesion molecule 2. (283 aa)
FBLN7Fibulin 7. (440 aa)
FAT4FAT atypical cadherin 4. (4962 aa)
wif1Hypoxia inducible factor 1 subunit alpha inhibitor. (393 aa)
egfUncharacterized protein. (1051 aa)
vwceUncharacterized protein. (1074 aa)
fbn1Abl interactor 1. (2882 aa)
VLDLRVery low density lipoprotein receptor. (878 aa)
hyal2Hyaluronidase. (491 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (679 aa)
NOTCH3Notch receptor 3. (2413 aa)
notch1Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2535 aa)
adam23Family with sequence similarity 155 member A. (815 aa)
hyal4Hyaluronidase. (503 aa)
adam9Polymerase (DNA) gamma, catalytic subunit. (863 aa)
kremen1-2Kringle containing transmembrane protein 1. (289 aa)
mfge8Myocyte enhancer factor 2D. (470 aa)
malrd1EPH receptor A6. (2096 aa)
cntnap4DEAD-box helicase 39A. (1269 aa)
tdgf1.1EGF-like domain-containing protein. (174 aa)
matn1Ubiquitin C-terminal hydrolase L1. (490 aa)
cntnap5Zinc finger CCCH-type containing 12B. (1290 aa)
FBN3Fibrillin 3. (2903 aa)
TENM1Teneurin transmembrane protein 1. (2761 aa)
GPR158G protein-coupled receptor 158. (1278 aa)
adam28.2Uncharacterized protein. (795 aa)
adam7EF-hand calcium-binding domain-containing protein 4A. (780 aa)
NID1Nidogen 1. (1230 aa)
THSD7AThrombospondin type 1 domain containing 7A. (1627 aa)
VwdeUncharacterized protein. (1274 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1131 aa)
relnG protein-coupled receptor 119. (3463 aa)
notch4Uncharacterized protein. (1581 aa)
tncAdenylate cyclase activating polypeptide 1 (pituitary). (1983 aa)
egfl8EGF-like-domain, multiple 8. (207 aa)
ENSXETP00000047701Eukaryotic translation initiation factor 3 subunit G. (1314 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1271 aa)
ankfn1lAnkyrin repeat and fibronectin type III domain containing 1 like. (364 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (800 aa)
lrp1bSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform. (4494 aa)
NRXN3Neurexin 3. (1715 aa)
tnrGRB2 associated binding protein 1. (1355 aa)
egfl7DNA topoisomerase III beta. (316 aa)
TNNTenascin N. (1093 aa)
megf10Multiple epidermal growth factor-like domains protein 10; Membrane receptor involved in phagocytosis. May also regulate homotypic retinal neuron repulsion. May play role in cell adhesion and motility. May also be an essential factor in the regulation of myogenesis, controlling the balance between skeletal muscle satellite cells proliferation and differentiation (By similarity); Belongs to the MEGF family. (1124 aa)
FBN2Fibrillin 2. (2874 aa)
hhipSecurin-like. (678 aa)
scarf1Tumor protein p53 binding protein 2. (890 aa)
platPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
ENSXETP00000043039Uncharacterized protein. (765 aa)
gas6Homeobox protein CDX-1. (672 aa)
LRP8LDL receptor related protein 8. (956 aa)
procMGC107972 protein. (456 aa)
LOC100145345LOC100145345 protein. (681 aa)
pigo-2Phosphatidylinositol glycan anchor biosynthesis class O. (2010 aa)
TEKTEK receptor tyrosine kinase. (1114 aa)
oit3Potassium channel, inwardly rectifying subfamily J, member 10. (546 aa)
UMODUncharacterized protein. (566 aa)
ENSXETP00000041023Uncharacterized protein. (606 aa)
ENSXETP00000040990Uncharacterized protein. (607 aa)
ENSXETP00000040926Uncharacterized protein. (514 aa)
dclk2Uncharacterized protein. (590 aa)
agkAcylglycerol kinase. (592 aa)
ADGRL4Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (731 aa)
celsr3Bone morphogenetic protein/retinoic acid inducible neural-specific 1; Belongs to the G-protein coupled receptor 2 family. (3713 aa)
astn2Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative). (1274 aa)
megf6Unc-5 netrin receptor B. (1426 aa)
EGFL6EGF like domain multiple 6. (546 aa)
ltbp1Progestin and adipoQ receptor family member VIII. (1673 aa)
FBLN2Fibulin 2. (944 aa)
nrxn2Glycine decarboxylase. (1692 aa)
mmrn1Intraflagellar transport protein 22 homolog. (1040 aa)
pparg-2Collagen type XI alpha 2 pseudogene 1. (511 aa)
HGFACHGF activator. (634 aa)
c6.2SSU72 homolog, RNA polymerase II CTD phosphatase. (934 aa)
nrg1GATA zinc finger domain containing 2A. (621 aa)
ATRNAttractin. (1361 aa)
astn1Astrotactin. (1302 aa)
NRXN1Uncharacterized protein. (974 aa)
cubnWD repeat domain 81. (3600 aa)
tecta.1Uncharacterized protein. (2124 aa)
f12Calcitonin gene-related peptide type 1 receptor; Belongs to the peptidase S1 family. (585 aa)
sorl1Tubulin tyrosine ligase like 4. (2146 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (1043 aa)
celsr2Immunoglobin superfamily member 21; Belongs to the G-protein coupled receptor 2 family. (2911 aa)
slit2ATPase family, AAA domain containing 3A. (1564 aa)
thbs4Uncharacterized protein. (970 aa)
THBS1Thrombospondin 1. (1188 aa)
LOC100493382Major facilitator superfamily domain containing 6; Cadherins are calcium-dependent cell adhesion proteins. (2690 aa)
adam22Uncharacterized protein. (918 aa)
habp2EF-hand calcium binding domain 8. (617 aa)
VCANVersican. (3727 aa)
crb2EMI domain containing 1. (1456 aa)
thbs3Uncharacterized protein. (850 aa)
muc4Uncharacterized protein. (1798 aa)
slit1Slit1 protein. (1529 aa)
edil3Vomeronasal receptor B-1. (482 aa)
BTCBetacellulin. (170 aa)
LOC100485319Crystallin mu. (843 aa)
umod.3Uromodulin (uromucoid, Tamm-Horsfall glycoprotein), gene 3. (1099 aa)
c8bModulator of smoothened. (573 aa)
LOC7337285'-aminolevulinate synthase 1. (142 aa)
ltbp4Acyl-CoA synthetase family member 3. (1342 aa)
galns-2Galactosamine (N-acetyl)-6-sulfatase. (784 aa)
CRELD2Cysteine rich with EGF like domains 2. (355 aa)
cntnap1LOC100037844 protein. (1326 aa)
HBEGFHeparin binding EGF like growth factor. (195 aa)
cntnap2Sp8 transcription factor. (1338 aa)
LOC100493268Hyaluronan and proteoglycan link protein 3. (1706 aa)
comptRNA phosphotransferase 1. (704 aa)
adgre2Homeobox D10. (508 aa)
MATN3Matrilin 3. (378 aa)
MGC89178MGC89178 protein. (476 aa)
ptgs2EGF-like domain-containing protein. (619 aa)
matn2Uncharacterized protein. (894 aa)
vasnVasorin; May act as an inhibitor of TGF-beta signaling. (673 aa)
FAT3FAT atypical cadherin 3. (4579 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3479 aa)
thbdAldehyde dehydrogenase 9 family member A1. (542 aa)
dnerMicrosomal glutathione S-transferase 3. (669 aa)
cd93Retbindin. (573 aa)
nell2Protein kinase C-binding protein NELL2. (827 aa)
scube2Uncharacterized protein. (976 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
fat1Harvey rat sarcoma viral oncogene homolog. (4664 aa)
tmem8aBOC cell adhesion associated, oncogene regulated. (742 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (1017 aa)
nagpaMethionine sulfoxide reductase A, gene 1. (593 aa)
tmeff1DnaJ heat shock protein family (Hsp40) member C21. (372 aa)
matn4H2A histone family member Z. (702 aa)
prps1-2Uncharacterized protein. (455 aa)
aregEGF-like domain-containing protein. (226 aa)
eregNIMA-related kinase 6. (156 aa)
epgnLeucine-rich repeats and calponin homology (CH) domain containing 1. (138 aa)
mep1bMeprin A subunit. (722 aa)
NTNG2Netrin G2. (689 aa)
slit3ZXD family zinc finger C. (1519 aa)
NTNG1Netrin G1. (465 aa)
fat2Inner centromere protein. (4296 aa)
dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (740 aa)
rimkla-2Endoplasmic reticulum junction formation protein lunapark. (205 aa)
tmeff2Hydroxysteroid (17-beta) dehydrogenase 10. (354 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2981 aa)
TENM2Teneurin transmembrane protein 2. (2624 aa)
lrp4Glycoprotein A33 (transmembrane). (1832 aa)
adam19TBC1 domain family member 32. (911 aa)
NCANNeurocan. (628 aa)
adam11Uncharacterized protein. (764 aa)
tgfaSolute carrier family 6 (neurotransmitter transporter), member 8 like. (163 aa)
agrnSOS Ras/Rac guanine nucleotide exchange factor 1. (2105 aa)
cd248Iroquois-class homeodomain protein irx-4. (726 aa)
crb1MSS51 mitochondrial translational activator. (1341 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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