STRINGSTRING
GDF9 GDF9 inhbc.1 inhbc.1 bmp2 bmp2 bmp6 bmp6 INHBA INHBA GDF7 GDF7 gdf6 gdf6 BMP10 BMP10 bmp7.2 bmp7.2 gdf5 gdf5 ENSXETP00000010102 ENSXETP00000010102 gdf1 gdf1 TGFB2 TGFB2 gdnf gdnf AMH AMH nodal nodal mstn.2 mstn.2 mstn.1 mstn.1 bmp4 bmp4 lefty lefty bmp7.1 bmp7.1 tgfb1 tgfb1 INHBC INHBC artn artn bmp15 bmp15 admp admp bmp5 bmp5 gdf3 gdf3 INHBB INHBB NRTN NRTN bmp3 bmp3 GDF2 GDF2 gdf10 gdf10 admp2 admp2 inha inha nodal5 nodal5 nvl-2 nvl-2 LOC101734231 LOC101734231 LOC101734157 LOC101734157 nodal6 nodal6 bmp8 bmp8 nodal-2 nodal-2 nodal2 nodal2 nodal1 nodal1 gdf11.1 gdf11.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GDF9Growth differentiation factor 9. (421 aa)
inhbc.1Piwi-like RNA-mediated gene silencing 4. (367 aa)
bmp2Armadillo like helical domain containing 3. (398 aa)
bmp6Enhancer of mRNA decapping 4. (441 aa)
INHBAInhibin subunit beta A. (411 aa)
GDF7Growth differentiation factor 7. (414 aa)
gdf6Erb-b2 receptor tyrosine kinase 3. (396 aa)
BMP10Bone morphogenetic protein 10. (421 aa)
bmp7.2Nuclear receptor subfamily 5 group A member 1. (436 aa)
gdf5Growth differentiation factor 5. (496 aa)
ENSXETP00000010102TGF_BETA_2 domain-containing protein. (294 aa)
gdf1Vg1. (361 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (227 aa)
AMHAnti-Mullerian hormone. (606 aa)
nodalRibosomal protein S12. (418 aa)
mstn.2Ubiquitin associated protein 2. (374 aa)
mstn.1Lin-37 DREAM MuvB core complex component. (369 aa)
bmp4Zinc finger, HIT-type-containing 6. (469 aa)
leftyLeft-right determination factor. (365 aa)
bmp7.1TGF_BETA_2 domain-containing protein. (425 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
INHBCInhibin subunit beta C. (340 aa)
artnTGF_BETA_2 domain-containing protein. (401 aa)
bmp15Intraflagellar transport 74. (379 aa)
admpNovel protein similar to anti-dorsalizing morphogenic protein. (390 aa)
bmp5Apoptosis antagonizing transcription factor. (449 aa)
gdf3Derriere protein; Required for posterior mesoderm formation during embryogenesis. Acts indirectly to suppress head formation by altering mesodermal patterning. Also involved in the establishment of left-right axis asymmetry, acting upstream of nodal/nr-1. Can exert long-range effects in the embryo (By similarity). (354 aa)
INHBBInhibin subunit beta B. (131 aa)
NRTNNeurturin. (211 aa)
bmp3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (458 aa)
GDF2Growth differentiation factor 2. (410 aa)
gdf10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (442 aa)
admp2TGF_BETA_2 domain-containing protein. (432 aa)
inhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (371 aa)
nodal5Polypeptide N-acetylgalactosaminyltransferase 7. (386 aa)
nvl-2Nuclear VCP like. (393 aa)
LOC101734231Protein phosphatase, Mg2+/Mn2+ dependent 1F. (386 aa)
LOC101734157TGF_BETA_2 domain-containing protein. (386 aa)
nodal6TGF_BETA_2 domain-containing protein. (382 aa)
bmp8TGF_BETA_2 domain-containing protein. (419 aa)
nodal-2Nodal homolog 3-C; Exhibits mesoderm-dorsalizing activity and neural-inducing activity, but lacks mesoderm-inducing activity. Regulates the expression of specific mesodermal and neural genes. Induces convergent extension movements at the embryonic midline by activating the fgf signaling pathway to induce t/bra expression in the organizer region. Acts with wnt11 to induce Spemann organizer cells and induce axis formation (By similarity). The unprocessed protein antagonizes bmp- signaling; Belongs to the TGF-beta family. (403 aa)
nodal2Neurotrophic receptor tyrosine kinase 3. (405 aa)
nodal1Nodal homolog; Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Essential for mesoderm formation and axial patterning during embryonic development. Activates the activin-like signaling pathway to induce dorsal and ventral mesoderm in animal cap ectoderm. In addition, also dorsalizes ventral marginal zone (VMZ) tissues during gastrulation. Acts in a downstream signaling cascade via cripto and cer1 to mediate cardiogenesis in embryonic mesoderm. Directs the orientation of the left-right axis by driving the left-specific gene c [...] (403 aa)
gdf11.1ATR interacting protein. (425 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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