Your Input: | |
| | coro2b | Coronin-2B; May play a role in the reorganization of neuronal actin structure. (531 aa) |
| | SHKBP1 | SH3KBP1 binding protein 1. (815 aa) |
| | WDFY3 | WD repeat and FYVE domain containing 3. (3522 aa) |
| | wdr73 | Chitinase 1 (chitotriosidase). (374 aa) |
| | wdr41 | Coiled-coil domain containing 112. (469 aa) |
| | arpc1a | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (381 aa) |
| | THOC6 | THO complex 6. (352 aa) |
| | sec31a | Pregnancy-specific beta-1-glycoprotein 3. (1261 aa) |
| | wdr83 | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha (By similarity); Belongs to the WD repeat MORG1 family. (314 aa) |
| | nup214 | Forkhead box L1. (2070 aa) |
| | gga1-2 | Golgi-associated, gamma adaptin ear containing, ARF binding protein 1. (202 aa) |
| | elovl5-2 | Elongation of very long chain fatty acids protein 5. (431 aa) |
| | LOC100158595 | High choriolytic enzyme 2. (427 aa) |
| | bhlhe40-2 | Protein zwilch homolog. (436 aa) |
| | LOC101734139 | HYDIN, axonemal central pair apparatus protein. (467 aa) |
| | ENSXETP00000011593 | WD_REPEATS_REGION domain-containing protein. (91 aa) |
| | ENSXETP00000011604 | WD_REPEATS_REGION domain-containing protein. (139 aa) |
| | prpf4 | WD_REPEATS_REGION domain-containing protein. (340 aa) |
| | wdr7 | LOC100036723 protein. (1486 aa) |
| | wdr89 | Novel protein containing three WD domain, G-beta repeats. (383 aa) |
| | WDR11 | WD repeat domain 11. (1099 aa) |
| | wdr17 | Transcription activation suppressor. (1315 aa) |
| | SEC31B | SEC31 homolog B, COPII coat complex component. (1211 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (547 aa) |
| | ap1s3 | Uncharacterized protein. (533 aa) |
| | HIRA | Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1058 aa) |
| | elp2 | Elongator complex protein 2; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs; Belongs to the WD repeat ELP2 family. (832 aa) |
| | LOC101730828 | Uncharacterized protein. (1278 aa) |
| | birc6 | Poly(ADP-ribose) polymerase family member 3. (4839 aa) |
| | dcaf7 | WD repeat domain 68. (342 aa) |
| | wdr61 | WD repeat-containing protein 61. (305 aa) |
| | RRP9 | Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (493 aa) |
| | wdhd1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (1131 aa) |
| | wdr66 | Tripeptidyl peptidase 2. (972 aa) |
| | seh1l | Nucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Belongs to the WD repeat SEC13 family. (383 aa) |
| | LOC733932 | Novel protein containing four WD domain, G-beta repeats. (490 aa) |
| | gnb3 | Zinc finger, BED-type-containing 8. (349 aa) |
| | fbxw7 | Uncharacterized protein. (773 aa) |
| | wdr26 | WD repeat-containing protein 26; G-beta-like protein involved in cell signal transduction. Acts as a negative regulator in MAPK signaling pathway. Functions as a scaffolding protein to promote G beta:gamma-mediated PLCB2 plasma membrane translocation and subsequent activation in leukocytes. Core component of the CTLH E3 ubiquitin-protein ligase complex that mediates ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts as a negative regulator of the canonical Wnt signaling pathway through preventing ubiquitination of beta-catenin CTNNB1 by the b [...] (626 aa) |
| | ercc8 | Excision repair cross-complementing rodent repair deficiency, complementation group 8. (399 aa) |
| | wdr53 | Cdk5 and Abl enzyme substrate 2. (359 aa) |
| | dcaf13 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity). (518 aa) |
| | snrnp40 | Wdr57 protein. (337 aa) |
| | wdr48 | WD repeat-containing protein 48; Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. May play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes. (709 aa) |
| | wdr3 | WD_REPEATS_REGION domain-containing protein. (941 aa) |
| | wsb1 | WD repeat and SOCS box-containing protein 1; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. (422 aa) |
| | adi1 | EARP-interacting protein homolog; Belongs to the WD repeat EIPR1 family. (513 aa) |
| | plrg1 | Signal transducing adaptor molecule. (543 aa) |
| | dnai2 | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3. (611 aa) |
| | wsb2 | Uncharacterized protein. (418 aa) |
| | fbxw4 | ZFP64 zinc finger protein. (425 aa) |
| | kif21a | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1670 aa) |
| | katnb1 | Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (668 aa) |
| | dcaf5 | Membrane associated ring-CH-type finger 5. (939 aa) |
| | btrc | Uncharacterized protein. (600 aa) |
| | ift140 | Uncharacterized protein. (1461 aa) |
| | tbc1d7 | Phospholipase A2 group VI. (390 aa) |
| | LOC101734719 | WD_REPEATS_REGION domain-containing protein. (361 aa) |
| | LOC100491248 | TAR DNA-binding protein 43. (378 aa) |
| | tbl3 | Speckle targeted PIP5K1A-regulated poly(A) polymerase. (774 aa) |
| | ppp2r2c | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (472 aa) |
| | dffa | DNA fragmentation factor, 45kDa, alpha polypeptide. (372 aa) |
| | atg16l2 | Pyruvate dehydrogenase E1 alpha 1 subunit. (593 aa) |
| | mios | Zinc_ribbon_16 domain-containing protein. (886 aa) |
| | wdr45b | WD repeat domain phosphoinositide-interacting protein 3; Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. In the cellular response to starvation, may also function in the inhibition of the mTORC1 signaling pathway. Belongs to the WD repeat SVP1 family. (344 aa) |
| | AAAS | Aladin WD repeat nucleoporin. (519 aa) |
| | nbeal2 | Solute carrier family 7 member 14. (2705 aa) |
| | AHI1 | Abelson helper integration site 1. (747 aa) |
| | wdr55-2 | WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (399 aa) |
| | LLGL1 | LLGL scribble cell polarity complex component 1. (1052 aa) |
| | EML6 | EMAP like 6. (1958 aa) |
| | dync1i2 | Cysteine-serine-rich nuclear protein 2. (644 aa) |
| | dcaf8 | DDB1- and CUL4-associated factor 8. (604 aa) |
| | wdr1 | WD repeat-containing protein 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Doesn't sever actin filaments alone, but caps the barbed ends of filaments severed by cofilin, which blocks annealing and depolymerization and allows more extensive severing by cofilin (By similarity); Belongs to the WD repeat AIP1 family. (609 aa) |
| | grwd1 | Zinc finger SWIM-type containing 5. (471 aa) |
| | coro2a | Coronin; Belongs to the WD repeat coronin family. (545 aa) |
| | gnb1 | Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa) |
| | tbl2 | C-X-C motif chemokine receptor 5. (436 aa) |
| | rbbp4 | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. (456 aa) |
| | rptor | WD_REPEATS_REGION domain-containing protein. (1356 aa) |
| | nup37 | Protein kinase C iota. (326 aa) |
| | rfwd3 | Heat shock 70 kDa protein 14. (752 aa) |
| | wipi2 | 2-hydroxyacyl-CoA lyase 1. (449 aa) |
| | wdr59 | Damage-specific DNA binding protein 1. (964 aa) |
| | coro7 | Coronin; Belongs to the WD repeat coronin family. (926 aa) |
| | dtl | Denticleless protein homolog; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2. CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. [...] (750 aa) |
| | ENSXETP00000028716 | Uncharacterized protein. (541 aa) |
| | WDR35 | WD repeat-containing protein 35. (1181 aa) |
| | zhx2 | TBC1 domain family member 31. (1872 aa) |
| | utp18 | WD_REPEATS_REGION domain-containing protein. (528 aa) |
| | dcaf6 | Uncharacterized protein. (812 aa) |
| | EDC4 | Enhancer of mRNA decapping 4. (1383 aa) |
| | wdr37 | WD repeat-containing protein 37. (540 aa) |
| | LOC101732357 | Fer-1-like family member 4, pseudogene (functional). (691 aa) |
| | gtf3c2 | Coiled-coil domain containing 82. (938 aa) |
| | utp4 | Cirrhosis, autosomal recessive 1A (Cirhin). (690 aa) |
| | strn | WD_REPEATS_REGION domain-containing protein. (820 aa) |
| | fzr1 | Mucolipin 1. (624 aa) |
| | FBXW8 | F-box and WD repeat domain containing 8. (657 aa) |
| | KCTD3 | Potassium channel tetramerization domain containing 3. (862 aa) |
| | rbbp5 | ALG2, alpha-1,3/1,6-mannosyltransferase. (535 aa) |
| | fbxw9 | Exocyst complex component 5. (438 aa) |
| | atg16l1 | Autophagy-related protein 16; Plays an essential role in autophagy: interacts with ATG12- ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane; Belongs to the WD repeat ATG16 family. (622 aa) |
| | GEMIN5 | Gem nuclear organelle associated protein 5. (1473 aa) |
| | WDPCP | WD repeat containing planar cell polarity effector. (708 aa) |
| | WDR43 | WD repeat domain 43. (708 aa) |
| | arpc1b | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (383 aa) |
| | PHIP | Pleckstrin homology domain interacting protein. (1835 aa) |
| | nwd2 | Heat shock protein 90kDa alpha family class B member 1. (1742 aa) |
| | ambra1 | Suppressor of cytokine signaling 6. (1304 aa) |
| | ENSXETP00000032567 | WD_REPEATS_REGION domain-containing protein. (1650 aa) |
| | wdr74 | WD_REPEATS_REGION domain-containing protein. (421 aa) |
| | wdr38 | WD_REPEATS_REGION domain-containing protein. (231 aa) |
| | tm4sf4-2 | Transmembrane 4 L six family member 4. (375 aa) |
| | ENSXETP00000033645 | WD_REPEATS_REGION domain-containing protein. (374 aa) |
| | ENSXETP00000033698 | Uncharacterized protein. (613 aa) |
| | LOC101734025 | DEAD-box helicase 3 Y-linked. (462 aa) |
| | LOC108644804 | WD_REPEATS_REGION domain-containing protein. (313 aa) |
| | LOC101732312 | WD_REPEATS_REGION domain-containing protein. (445 aa) |
| | LOC100488540 | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (357 aa) |
| | wdr75 | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled. (833 aa) |
| | preb | Rho GTPase activating protein 18. (296 aa) |
| | ciao1 | Probable cytosolic iron-sulfur protein assembly protein ciao1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. (335 aa) |
| | gnb4 | LOC549706 protein. (327 aa) |
| | wdr60 | WD repeat domain 60. (1116 aa) |
| | mlst8 | Target of rapamycin complex subunit lst8. (347 aa) |
| | wdr81 | F-box/LRR-repeat protein 15. (1888 aa) |
| | ift80 | Intraflagellar transport 80 homolog. (779 aa) |
| | wdr70 | WD repeat-containing protein 70; Belongs to the WD repeat GAD-1 family. (627 aa) |
| | LOC100498290 | WD_REPEATS_REGION domain-containing protein. (881 aa) |
| | kif21b | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1623 aa) |
| | cfap43 | Docking protein 4. (1660 aa) |
| | WDR76 | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (600 aa) |
| | THOC3 | THO complex 3. (364 aa) |
| | cdc40 | Insulin receptor. (577 aa) |
| | chaf1b | Arginine vasopressin induced 1. (568 aa) |
| | WDR88 | WD repeat domain 88. (369 aa) |
| | brwd1 | Chromatin assembly factor 1 subunit B. (1318 aa) |
| | dcaf11 | DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family. (537 aa) |
| | WDFY2 | WD repeat and FYVE domain containing 2. (404 aa) |
| | cdc20b | VPS54 GARP complex subunit. (519 aa) |
| | DMXL1 | Dmx like 1. (3058 aa) |
| | med16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (829 aa) |
| | pafah1b1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (414 aa) |
| | smu1 | WD40 repeat-containing protein SMU1; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Required for normal accumulation of ik (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). Belongs to the WD repeat SMU1 family. (513 aa) |
| | wdr18 | WD repeat domain 18. (428 aa) |
| | tulp4 | B-cell receptor CD22-like. (1568 aa) |
| | poc1a | POC1 centriolar protein homolog A; May play an important role in centriole assembly and/or stability and ciliogenesis. (441 aa) |
| | plaa | Uncharacterized protein. (799 aa) |
| | bub3 | Uncharacterized protein. (342 aa) |
| | nedd1 | WD_REPEATS_REGION domain-containing protein. (672 aa) |
| | fbxw2 | WD_REPEATS_REGION domain-containing protein. (291 aa) |
| | eml1 | Uncharacterized protein. (815 aa) |
| | wrap73 | Uncharacterized protein. (451 aa) |
| | ppp2r2a | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (427 aa) |
| | wdr36 | Nuclear factor of activated T cells 1. (896 aa) |
| | ddb2 | DNA damage-binding protein 2; Required for DNA repair. Binds to ddb1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. Also appears to function as the substrate recognition module for a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex which may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV- induced DNA damage. The ubiquitination of histones may facilitate their removal from th [...] (501 aa) |
| | taf5l | Relaxin family peptide receptor 3. (588 aa) |
| | utp15 | U3 small nucleolar RNA-associated protein 15 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. (525 aa) |
| | traf7 | Uncharacterized protein. (681 aa) |
| | gnb1l | WD_REPEATS_REGION domain-containing protein. (327 aa) |
| | ntf4-2 | Neurotrophin 4. (1598 aa) |
| | wdr6 | Brain abundant membrane attached signal protein 1. (1109 aa) |
| | BRWD3 | Bromodomain and WD repeat domain containing 3. (1775 aa) |
| | prpf19 | Protein LSM14 homolog A. (440 aa) |
| | nsmaf | Uncharacterized protein. (917 aa) |
| | LRBA | LPS responsive beige-like anchor protein. (2824 aa) |
| | wdr5 | WD repeat-containing protein 5; Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity). (334 aa) |
| | LOC101734744 | Uncharacterized protein. (992 aa) |
| | nol10 | Nucleolar protein 10. (704 aa) |
| | Wdfy4 | Uncharacterized protein. (542 aa) |
| | ppp2r2b | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Negatively control the initiation of oocyte maturation (By similarity). (468 aa) |
| | tep1 | Heparan sulfate-glucosamine 3-sulfotransferase 5. (2665 aa) |
| | wdr72 | Sodium voltage-gated channel beta subunit 2. (975 aa) |
| | scap | LOC100145201 protein. (1319 aa) |
| | ppp2r2d | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform; B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing ppp2r2d (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ensa and arpp19 inhibitors. PP2A complexes containing ppp2r2d (PR55-delta) also regulate the activity of TGF-beta/Activin/Nodal signaling by restri [...] (452 aa) |
| | wdr34 | RWD domain containing 2B. (503 aa) |
| | PPWD1 | Peptidylprolyl isomerase domain and WD repeat containing 1. (643 aa) |
| | tbl1xr1 | Uncharacterized protein. (543 aa) |
| | poc1b | POC1 centriolar protein homolog B; Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Belongs to the WD repeat POC1 family. (470 aa) |
| | wdr77 | Chromosome 11 open reading frame 68. (323 aa) |
| | wdr49 | Wdr49 protein. (1051 aa) |
| | coro1c | Coronin; Belongs to the WD repeat coronin family. (751 aa) |
| | tbl1x | Uncharacterized protein. (565 aa) |
| | tle4 | F-box and WD repeat domain containing 4. (774 aa) |
| | rack1 | Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1. (317 aa) |
| | copa | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1240 aa) |
| | tle1 | Uncharacterized protein. (780 aa) |
| | SPAG16 | Sperm associated antigen 16. (423 aa) |
| | cop1 | Uncharacterized protein. (695 aa) |
| | eml2 | Coiled-coil domain containing 81. (910 aa) |
| | LYST | Lysosomal trafficking regulator. (3713 aa) |
| | wdr91 | WD repeat-containing protein 91; Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport; Belongs to the WD repeat WDR91 family. (751 aa) |
| | WDR25 | WD repeat domain 25. (483 aa) |
| | sec13 | SEC13-like 1 (S. cerevisiae); Belongs to the WD repeat SEC13 family. (320 aa) |
| | WDR46 | WD repeat domain 46. (592 aa) |
| | thul16 | Transmembrane protein 178A. (403 aa) |
| | llgl2 | Lethal giant larvae homolog 2. (1019 aa) |
| | cfap52 | Guanylate cyclase 1, soluble, alpha 2. (640 aa) |
| | STXBP5 | Syntaxin binding protein 5. (1119 aa) |
| | cdc20 | WD_REPEATS_REGION domain-containing protein. (509 aa) |
| | cdrt1 | Polypyrimidine tract binding protein 2. (1065 aa) |
| | Wdr62 | Uncharacterized protein. (732 aa) |
| | cfap57 | Werner syndrome, RecQ helicase-like. (1250 aa) |
| | wdr20 | WD repeat domain 20. (586 aa) |
| | ift122 | Intraflagellar transport protein 122 homolog; Required for cilia formation during embryonal development. Acts as a negative regulator of Shh signaling. (1222 aa) |
| | TECPR2 | Tectonin beta-propeller repeat containing 2. (1396 aa) |
| | nwd1 | Protein phosphatase 1, regulatory (inhibitor) subunit 3C, gene 1. (1550 aa) |
| | coro6 | Coronin; Belongs to the WD repeat coronin family. (471 aa) |
| | wdr44 | Uncharacterized protein. (912 aa) |
| | wdr78 | cAMP responsive element binding protein 5. (795 aa) |
| | hps5 | Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1103 aa) |
| | znf106 | WD_REPEATS_REGION domain-containing protein. (1804 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | nup43 | Cysteine dioxygenase type 1. (375 aa) |
| | pex7 | Ring finger protein 157. (354 aa) |
| | HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4833 aa) |
| | nbeal1 | Nuclear receptor coactivator 6. (2691 aa) |
| | wdr12 | Ribosome biogenesis protein wdr12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (858 aa) |
| | gnb5 | TATA-box binding protein associated factor 13. (395 aa) |
| | dmxl2 | WD_REPEATS_REGION domain-containing protein. (3034 aa) |
| | Strn3 | Striatin 3. (798 aa) |
| | wdsub1 | Dynein axonemal heavy chain 14. (485 aa) |
| | eif3i | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (325 aa) |
| | nle1 | WD_REPEATS_REGION domain-containing protein. (486 aa) |
| | lrwd1 | Leucine-rich repeat and WD repeat-containing protein 1; Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post- replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability (By similarity); Belongs to the LRWD1 family. (691 aa) |
| | dennd3 | HAUS augmin-like complex subunit 7. (1274 aa) |
| | wdr86 | Failed axon connections homolog. (415 aa) |
| | twf2 | WD repeat-containing protein 82; Component of a chromatin regulatory complex involved in regulating chromatin structure in the nucleus; Belongs to the WD repeat SWD2 family. (594 aa) |
| | dcaf4 | GATA binding protein 4. (493 aa) |
| | wdr55 | Translocase of inner mitochondrial membrane 13 homolog. (142 aa) |
| | eed | Polycomb protein eed; Polycomb group (PcG) protein. Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). (444 aa) |
| | dcaf10 | DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat DCAF10 family. (457 aa) |
| | NBEA | Neurobeachin. (2935 aa) |
| | STXBP5L | Syntaxin binding protein 5 like. (1236 aa) |
| | aamp | Phospholipase A2 group XIIB. (475 aa) |
| | wdr24 | Rho/Rac guanine nucleotide exchange factor 18. (669 aa) |
| | eml4 | Echinoderm microtubule-associated protein-like 4; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; Belongs to the WD repeat EMAP family. (1028 aa) |
| | paaf1 | WD_REPEATS_REGION domain-containing protein. (406 aa) |
| | wdr45 | Uncharacterized protein. (366 aa) |
| | LOC100488585 | Mitogen-activated protein kinase kinase kinase 15. (385 aa) |
| | LOC101730808 | WD_REPEATS_REGION domain-containing protein. (411 aa) |
| | wdr90 | WD repeat-containing protein 90; Required for efficient primary cilium formation. Belongs to the WD repeat WDR90/POC16 family. (1850 aa) |
| | pwp1 | Solute carrier family 16, member 2 (thyroid hormone transporter). (515 aa) |
| | cstf1 | Cleavage stimulation factor, 3' pre-RNA, subunit 1. (431 aa) |
| | EML5 | EMAP like 5. (1907 aa) |
| | daw1 | Dynein assembly factor with WDR repeat domains 1; May play a role in axonemal outer row dynein assembly. Belongs to the WD repeat WDR69 family. (446 aa) |
| | efcab8 | Uncharacterized protein. (897 aa) |
| | eml3 | ATPase type 13A3. (893 aa) |
| | pik3r4 | Uncharacterized protein. (1361 aa) |
| | rbbp7 | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. (507 aa) |
| | tle2 | tRNA methyltransferase 12 homolog. (769 aa) |
| | vps11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (930 aa) |
| | copb2 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (920 aa) |
| | wdr19-2 | Cyclin-dependent kinase 8. (1298 aa) |
| | taf5 | Myeloid-associated differentiation marker homolog. (777 aa) |
| | wdr47 | MYCBP associated protein. (920 aa) |
| | strap | WD_REPEATS_REGION domain-containing protein. (260 aa) |
| | dync1i1 | Dync1i1 protein. (627 aa) |
| | wdtc1 | Transmembrane protein 178, gene 2. (671 aa) |
| | wdr92 | WD repeat-containing protein 92; Seems to act as a modulator of apoptosis. (633 aa) |
