STRINGSTRING
ercc6l ercc6l SKIV2L SKIV2L ythdc2 ythdc2 ddx19b ddx19b ddx17 ddx17 chd5 chd5 ddx23 ddx23 ddx47 ddx47 ddx39a ddx39a dhx57 dhx57 ddx55 ddx55 DDX59 DDX59 LOC100486072 LOC100486072 dhx16 dhx16 CHD3 CHD3 DDX51 DDX51 ddx43 ddx43 BTAF1 BTAF1 rad54l2 rad54l2 HELQ HELQ ENSXETP00000009992 ENSXETP00000009992 CHD6 CHD6 ddx41 ddx41 recql recql dhx34 dhx34 blm blm DDX28 DDX28 dhx58 dhx58 eif4a1 eif4a1 ddx39b ddx39b CHD1 CHD1 dhx8 dhx8 ddx10 ddx10 ddx6 ddx6 DDX46 DDX46 SMARCA4 SMARCA4 HLTF HLTF DHX30 DHX30 ATRX ATRX zranb3 zranb3 DDX54 DDX54 ddx11 ddx11 DDX58 DDX58 tdrd9 tdrd9 recql4 recql4 hells hells ddx21 ddx21 ddx52 ddx52 polq polq ddx42 ddx42 FANCM FANCM smarca1 smarca1 DDX31 DDX31 DHX36 DHX36 rad54b rad54b chd8 chd8 eif4a3.1 eif4a3.1 DHX38 DHX38 dhx9 dhx9 ddx49 ddx49 ddx5 ddx5 SNRNP200 SNRNP200 LOC100145162 LOC100145162 chd4 chd4 ep400 ep400 wrn wrn DHX29 DHX29 MTREX MTREX ddx4 ddx4 smarca5 smarca5 smarcad1 smarcad1 eif4a2 eif4a2 dhx35 dhx35 ercc2 ercc2 ddx3x ddx3x dhx15 dhx15 map1lc3a-2 map1lc3a-2 DDX27 DDX27 clec3b-2 clec3b-2 DDX20 DDX20 CHD7 CHD7 DDX24 DDX24 dhx40 dhx40 LOC101733299 LOC101733299 dicer1 dicer1 recql5 recql5 psmb5-2 psmb5-2 ddx25 ddx25 ddx56 ddx56 rcn3-2 rcn3-2 ercc3 ercc3 slc9a1-2 slc9a1-2 rad54l rad54l brip1 brip1 smarcal1 smarcal1 hfm1 hfm1 chd2 chd2 IFIH1 IFIH1 INO80 INO80 smarca2 smarca2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ercc6lPutative ortholog of ancient conserved domain protein 2, 2 of 2. (1361 aa)
SKIV2LSki2 like RNA helicase. (1249 aa)
ythdc2Serine/threonine-protein kinase Sgk1. (1419 aa)
ddx19bUncharacterized protein. (512 aa)
ddx17Uncharacterized protein; Belongs to the DEAD box helicase family. (609 aa)
chd5HNF1 homeobox B. (1782 aa)
ddx23Ankyrin repeat domain 9. (808 aa)
ddx47Marker of proliferation Ki-67; Belongs to the DEAD box helicase family. (466 aa)
ddx39aUncharacterized protein. (449 aa)
dhx57Uncharacterized protein. (1408 aa)
ddx55RNA helicase. (597 aa)
DDX59DEAD-box helicase 59. (709 aa)
LOC100486072Phosphomannomutase 1. (820 aa)
dhx16Uncharacterized protein. (1034 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2035 aa)
DDX51DEAD-box helicase 51; Belongs to the DEAD box helicase family. (671 aa)
ddx43DEAD (Asp-Glu-Ala-Asp) box polypeptide 53; Belongs to the DEAD box helicase family. (666 aa)
BTAF1B-TFIID TATA-box binding protein associated factor 1. (1823 aa)
rad54l2Helicase ARIP4; DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner; Belongs to the SNF2/RAD54 helicase family. (1396 aa)
HELQHelicase, POLQ like. (1000 aa)
ENSXETP00000009992Cysteine-rich secretory protein 3. (3566 aa)
CHD6Chromodomain helicase DNA binding protein 6. (2667 aa)
ddx41Meprin A subunit alpha. (614 aa)
recqlATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (648 aa)
dhx34Uncharacterized protein. (1142 aa)
blmUncharacterized protein. (1365 aa)
DDX28DEAD-box helicase 28. (480 aa)
dhx58Glucosidase, alpha; acid. (686 aa)
eif4a1Uncharacterized protein; Belongs to the DEAD box helicase family. (415 aa)
ddx39bEnolase superfamily member 1. (449 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1748 aa)
dhx8Ribosomal protein S15a. (1213 aa)
ddx10RNA helicase. (852 aa)
ddx6Probable ATP-dependent RNA helicase ddx6; ATP-dependent RNA helicase that is an integral component of messenger ribonucleoprotein complexes (mRNPs), storage particles that mask maternal mRNAs from the translational apparatus during oocyte maturation; Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. (486 aa)
DDX46DEAD-box helicase 46. (936 aa)
SMARCA4Uncharacterized protein. (1608 aa)
HLTFHelicase like transcription factor. (991 aa)
DHX30DExH-box helicase 30. (799 aa)
ATRXATRX chromatin remodeler. (2268 aa)
zranb3RE1 silencing transcription factor. (1081 aa)
DDX54ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (847 aa)
ddx11Carnitine O-acetyltransferase b. (899 aa)
DDX58DExD/H-box helicase 58. (921 aa)
tdrd9Protein phosphatase 4 regulatory subunit 1. (1346 aa)
recql4Integrator complex subunit 10. (1463 aa)
hellsUncharacterized protein. (840 aa)
ddx21Nuclear autoantigenic sperm protein (histone-binding). (758 aa)
ddx52Phosphorylase kinase, gamma 1 (muscle). (634 aa)
polqUncharacterized protein. (2671 aa)
ddx42Cullin 2. (937 aa)
FANCMFA complementation group M. (2232 aa)
smarca1Annexin A4. (1025 aa)
DDX31RNA helicase. (637 aa)
DHX36DEAH-box helicase 36. (1006 aa)
rad54bUncharacterized protein. (897 aa)
chd8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/tp53-mediated apoptosis by recruiting histone H1 and preventing p53/tp53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (ctnnb1) activity. Negatively regulates ctnnb1-targeted gene expression by being recruited specifically to the promoter regions of several ctnnb1 responsive [...] (2206 aa)
eif4a3.1Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the [...] (415 aa)
DHX38DEAH-box helicase 38. (1222 aa)
dhx9U4/U6 small nuclear ribonucleoprotein Prp31. (1257 aa)
ddx49Uncharacterized protein; Belongs to the DEAD box helicase family. (482 aa)
ddx5Uncharacterized protein; Belongs to the DEAD box helicase family. (618 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2075 aa)
LOC100145162Diphthamide biosynthesis 3. (2919 aa)
chd4SON DNA binding protein. (1889 aa)
ep400Motilin receptor. (2734 aa)
wrnCell death-inducing p53-target protein 1. (1432 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1364 aa)
MTREXMtr4 exosome RNA helicase. (1035 aa)
ddx4Polymerase (DNA directed), gamma 2, accessory subunit; Belongs to the DEAD box helicase family. (678 aa)
smarca5Methyltransferase like 6. (1049 aa)
smarcad1La ribonucleoprotein domain family member 4B; DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double- strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs. Required for the restoration of heterochromatin organization after replication (By similarity). (1004 aa)
eif4a2Myb/SANT-like DNA-binding domain-containing protein 4; Belongs to the DEAD box helicase family. (412 aa)
dhx35Uncharacterized protein. (704 aa)
ercc2Epoxide hydrolase 3. (760 aa)
ddx3xUncharacterized protein; Belongs to the DEAD box helicase family. (744 aa)
dhx15ATPase, Ca++ transporting, type 2C, member 1. (761 aa)
map1lc3a-2GIPC PDZ domain containing family member 1. (2206 aa)
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (760 aa)
clec3b-2Uncharacterized protein. (1371 aa)
DDX20DEAD-box helicase 20. (814 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2969 aa)
DDX24DEAD-box helicase 24; Belongs to the DEAD box helicase family. (794 aa)
dhx40Nudix hydrolase 21. (782 aa)
LOC101733299VPS52, GARP complex subunit. (343 aa)
dicer1Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] (1899 aa)
recql5Uncharacterized protein. (1035 aa)
psmb5-2Chromodomain helicase DNA binding protein 9. (2874 aa)
ddx25Cytochrome P450 family 24 subfamily A member 1. (479 aa)
ddx56GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase. (552 aa)
rcn3-2Reticulocalbin 3. (1383 aa)
ercc3Uncharacterized protein. (806 aa)
slc9a1-2Solute carrier family 9 member 1. (465 aa)
rad54lUncharacterized protein. (773 aa)
brip1PH domain and leucine rich repeat protein phosphatase 2. (1229 aa)
smarcal1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA (By similarity); Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (941 aa)
hfm1Probable ATP-dependent DNA helicase HFM1; Required for crossover formation and complete synapsis of homologous chromosomes during meiosis; Belongs to the helicase family. SKI2 subfamily. (1402 aa)
chd2Uncharacterized protein. (1765 aa)
IFIH1Interferon induced with helicase C domain 1. (992 aa)
INO80INO80 complex ATPase subunit. (1547 aa)
smarca2General transcription factor IIIC subunit 2. (1588 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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