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entpd5 entpd5 nme3 nme3 nme2 nme2 nt5c2 nt5c2 nt5c1a nt5c1a Uckl1 Uckl1 uck2 uck2 dctpp1 dctpp1 ctps2 ctps2 cmpk1 cmpk1 dck.1 dck.1 nt5c3a nt5c3a dctd dctd rrm2b rrm2b LOC100485794 LOC100485794 Cda Cda upp1 upp1 cmpk2 cmpk2 CAD CAD ctps1 ctps1 nt5c3b nt5c3b hexb-2 hexb-2 entpd3 entpd3 NT5E NT5E nt5m nt5m pnp pnp tk1 tk1 ENTPD6 ENTPD6 cant1 cant1 dck.2 dck.2 upb1 upb1 UCK1 UCK1 dhodh dhodh entpd8 entpd8 tk2 tk2 upp2 upp2 tymp tymp nme6 nme6 entpd1 entpd1 rrm2.2 rrm2.2 rrm2.1 rrm2.1 dtymk dtymk tyms tyms NT5C1A NT5C1A rrm1 rrm1 dpyd dpyd entpd4 entpd4 dut-2 dut-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
entpd5Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (428 aa)
nme3SRY-box 8; Belongs to the NDK family. (188 aa)
nme2Nucleoside diphosphate kinase. (204 aa)
nt5c2Cytosolic purine 5'-nucleotidase; May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides (By similarity). (638 aa)
nt5c1aUncharacterized protein. (430 aa)
Uckl1Uncharacterized protein. (176 aa)
uck2Uridine-cytidine kinase 2; Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor (By similarity). (261 aa)
dctpp1dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (158 aa)
ctps2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (599 aa)
cmpk1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (219 aa)
dck.1Dck protein. (265 aa)
nt5c3a5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (334 aa)
dctdCMP/dCMP-type deaminase domain-containing protein. (190 aa)
rrm2bUncharacterized protein. (416 aa)
LOC100485794PfkB domain-containing protein. (720 aa)
CdaCytidine deaminase. (118 aa)
upp1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (311 aa)
cmpk2Tripartite motif containing 2. (459 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (1995 aa)
ctps1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (602 aa)
nt5c3b5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (290 aa)
hexb-2Hexosaminidase B (beta polypeptide). (176 aa)
entpd3Progesterone receptor membrane component 1; Belongs to the GDA1/CD39 NTPase family. (510 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (582 aa)
nt5mPotassium channel, voltage gated shaker related subfamily A, member 1. (227 aa)
pnpPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (297 aa)
tk1Thymidine kinase. (262 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (469 aa)
cant1Calcium activated nucleotidase 1. (400 aa)
dck.2Dpy-19-like 4. (265 aa)
upb1LOC100145317 protein. (383 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (292 aa)
dhodhDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (411 aa)
entpd8Forkhead box protein C2; Belongs to the GDA1/CD39 NTPase family. (478 aa)
tk2Kinectin 1. (279 aa)
upp2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (316 aa)
tympThymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (513 aa)
nme6Nucleoside diphosphate kinase 6; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (179 aa)
entpd1NEDD4 binding protein 2-like 1; Belongs to the GDA1/CD39 NTPase family. (536 aa)
rrm2.2Collagen, type VI, alpha 6. (447 aa)
rrm2.1Uncharacterized protein. (397 aa)
dtymkDeoxythymidylate kinase (Thymidylate kinase). (216 aa)
tymsCytochrome b-245, beta polypeptide. (308 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (364 aa)
rrm1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (786 aa)
dpydDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1028 aa)
entpd4Novel protein similar to cornifelin; Belongs to the GDA1/CD39 NTPase family. (621 aa)
dut-2dUTPase domain-containing protein. (212 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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