STRINGSTRING
ALDH1B1 ALDH1B1 bcat2 bcat2 aox1 aox1 aldh16a1 aldh16a1 PCCB PCCB dbt dbt acat2 acat2 hadh hadh agxt2 agxt2 LOC100496394 LOC100496394 ACADM ACADM mmut mmut bckdha bckdha aldh6a1 aldh6a1 hibadh hibadh mccc1 mccc1 ehhadh ehhadh ACAD8 ACAD8 echs1 echs1 abat abat LOC100493336 LOC100493336 hsd17b10 hsd17b10 HMGCLL1 HMGCLL1 bckdhb bckdhb aacs aacs aldh9a1 aldh9a1 aldh2 aldh2 oxct1 oxct1 hmgcs1 hmgcs1 acads acads PCCA PCCA acadsb acadsb acat1 acat1 il4i1 il4i1 mccc2 mccc2 DLD DLD hmgcl hmgcl acaa1 acaa1 aldh7a1 aldh7a1 aox1-2 aox1-2 LOC100497391 LOC100497391 hadha hadha hadhb hadhb hibch hibch ivd ivd mcee mcee aldh3a2 aldh3a2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (517 aa)
bcat2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
aox1Aldehyde oxidase 1. (1321 aa)
aldh16a1Uncharacterized protein; Belongs to the aldehyde dehydrogenase family. (842 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (561 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (540 aa)
acat2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
hadhVPS41, HOPS complex subunit. (315 aa)
agxt2Recoverin, gene 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (508 aa)
LOC100496394Amine oxidase. (510 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (481 aa)
mmutCalmodulin regulated spectrin associated protein family member 3. (813 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (433 aa)
aldh6a1Toll like receptor 3. (548 aa)
hibadh3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (368 aa)
mccc1Heterochromatin protein 1, binding protein 3. (716 aa)
ehhadhTransmembrane protein 255A; Belongs to the enoyl-CoA hydratase/isomerase family. (727 aa)
ACAD8Acyl-CoA dehydrogenase family member 8. (427 aa)
echs1Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (287 aa)
abatLOC100158654 protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
LOC100493336FAD-binding PCMH-type domain-containing protein. (1106 aa)
hsd17b10Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (294 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (336 aa)
bckdhbChymotrypsin like elastase 2A. (398 aa)
aacsAcetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA. (727 aa)
aldh9a1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (527 aa)
aldh2Aldedh domain-containing protein. (502 aa)
oxct1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (546 aa)
hmgcs13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (545 aa)
acadsUncharacterized protein. (412 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (723 aa)
acadsbUncharacterized protein. (429 aa)
acat1Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] (470 aa)
il4i1Amine oxidase. (530 aa)
mccc2Uncharacterized protein. (566 aa)
DLDDihydrolipoyl dehydrogenase. (536 aa)
hmgclLayilin. (363 aa)
acaa1Neuroligin 3; Belongs to the thiolase-like superfamily. Thiolase family. (447 aa)
aldh7a1SMAD family member 7; Belongs to the aldehyde dehydrogenase family. (539 aa)
aox1-2Uncharacterized protein. (1322 aa)
LOC100497391LanC like 3. (582 aa)
hadhaUncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (771 aa)
hadhbTrifunctional enzyme subunit beta, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (470 aa)
hibch3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity); Belongs to the enoyl-CoA hydratase/isomerase family. (587 aa)
ivdUncharacterized protein. (441 aa)
mceeVOC domain-containing protein. (174 aa)
aldh3a2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (577 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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