STRINGSTRING
LOC100497276 LOC100497276 aldh5a1 aldh5a1 L2HGDH L2HGDH acat2 acat2 hadh hadh bdh1 bdh1 gad1.1 gad1.1 bdh2 bdh2 ehhadh ehhadh acsm3 acsm3 echs1 echs1 abat abat gad1.2 gad1.2 HMGCLL1 HMGCLL1 aacs aacs oxct1 oxct1 hmgcs1 hmgcs1 acads acads acat1 acat1 hmgcl hmgcl gad2 gad2 hadha hadha
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100497276Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (363 aa)
aldh5a1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (526 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase. (453 aa)
acat2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
hadhVPS41, HOPS complex subunit. (315 aa)
bdh1ATPase type 13A1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (346 aa)
gad1.1Matrix-remodelling-associated 5. (600 aa)
bdh2Neogenin 1. (280 aa)
ehhadhTransmembrane protein 255A; Belongs to the enoyl-CoA hydratase/isomerase family. (727 aa)
acsm3ATPase, class I, type 8B, member 4. (583 aa)
echs1Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (287 aa)
abatLOC100158654 protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
gad1.2Cadherin 22. (581 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (336 aa)
aacsAcetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA. (727 aa)
oxct1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (546 aa)
hmgcs13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (545 aa)
acadsUncharacterized protein. (412 aa)
acat1Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] (470 aa)
hmgclLayilin. (363 aa)
gad2Peptidoglycan recognition protein 1. (588 aa)
hadhaUncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (771 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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