Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HMGCR | acat1 | ENSXETP00000039220 | ENSXETP00000040870 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 0.692 |
| HMGCR | acat2 | ENSXETP00000039220 | ENSXETP00000010125 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.540 |
| HMGCR | dhdds | ENSXETP00000039220 | ENSXETP00000037669 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Alkyl transferase; Belongs to the UPP synthase family. | 0.560 |
| HMGCR | fdps | ENSXETP00000039220 | ENSXETP00000034629 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.865 |
| HMGCR | fntb | ENSXETP00000039220 | ENSXETP00000049363 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | 0.436 |
| HMGCR | ggps1 | ENSXETP00000039220 | ENSXETP00000046271 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Protocadherin 8; Belongs to the FPP/GGPP synthase family. | 0.796 |
| HMGCR | hmgcs1 | ENSXETP00000039220 | ENSXETP00000037965 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.999 |
| HMGCR | idi1 | ENSXETP00000039220 | ENSXETP00000007983 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | DNA replication ATP-dependent helicase/nuclease DNA2. | 0.881 |
| HMGCR | mvd | ENSXETP00000039220 | ENSXETP00000046279 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.829 |
| HMGCR | mvk | ENSXETP00000039220 | ENSXETP00000032734 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.996 |
| HMGCR | nus1 | ENSXETP00000039220 | ENSXETP00000027518 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | PTPRF interacting protein, binding protein 2 (liprin beta 2). | 0.560 |
| HMGCR | pdss1 | ENSXETP00000039220 | ENSXETP00000047799 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.550 |
| HMGCR | pdss2 | ENSXETP00000039220 | ENSXETP00000035282 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Hydroxysteroid 11-beta-dehydrogenase 1-like protein; Belongs to the FPP/GGPP synthase family. | 0.550 |
| ICMT | fnta | ENSXETP00000021007 | ENSXETP00000037503 | Protein-S-isoprenylcysteine O-methyltransferase. | Zinc finger CCHC-type containing 17. | 0.746 |
| ICMT | fntb | ENSXETP00000021007 | ENSXETP00000049363 | Protein-S-isoprenylcysteine O-methyltransferase. | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | 0.527 |
| ICMT | mvd | ENSXETP00000021007 | ENSXETP00000046279 | Protein-S-isoprenylcysteine O-methyltransferase. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.499 |
| ICMT | mvk | ENSXETP00000021007 | ENSXETP00000032734 | Protein-S-isoprenylcysteine O-methyltransferase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.519 |
| ICMT | rce1 | ENSXETP00000021007 | ENSXETP00000010275 | Protein-S-isoprenylcysteine O-methyltransferase. | RCE1 homolog, prenyl protein peptidase (S. cerevisiae). | 0.974 |
| ICMT | zmpste24 | ENSXETP00000021007 | ENSXETP00000028951 | Protein-S-isoprenylcysteine O-methyltransferase. | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. | 0.974 |
| acat1 | HMGCR | ENSXETP00000040870 | ENSXETP00000039220 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.692 |
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