STRINGSTRING
gtf2e1.2 gtf2e1.2 taf13 taf13 taf5 taf5 tbpl2 tbpl2 gtf2a1 gtf2a1 tbp tbp ccnh ccnh taf7 taf7 tbpl1 tbpl1 gtf2f2 gtf2f2 gtf2h1 gtf2h1 gtf2e2 gtf2e2 gtf2e1 gtf2e1 taf12 taf12 gtf2h3 gtf2h3 TAF2 TAF2 taf15 taf15 taf1 taf1 taf8 taf8 taf5l taf5l ercc2 ercc2 gtf2a2 gtf2a2 mnat1 mnat1 gtf2h2 gtf2h2 TAF6L TAF6L gtf2a1l gtf2a1l TAF3 TAF3 TAF9 TAF9 ercc3 ercc3 gtf2b gtf2b TAF4B TAF4B gtf2h4 gtf2h4 taf11 taf11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gtf2e1.2General transcription factor IIE, polypeptide 1, alpha 56kDa, gene 2. (421 aa)
taf13Sorting and assembly machinery component 50 homolog. (144 aa)
taf5Myeloid-associated differentiation marker homolog. (777 aa)
tbpl2TATA box-binding protein-like protein 2; TATA box-binding transcription factor. Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis. Required for gastrulation. Regulates a large subset of genes that are ventrally expressed (By similarity). Binds to a subset of promoters. (322 aa)
gtf2a1General transcription factor IIA, 1. (367 aa)
tbpTATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis (By similarity). Binds to the promoters of select genes. (298 aa)
ccnhSAFB-like, transcription modulator; Belongs to the cyclin family. (323 aa)
taf7TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa. (349 aa)
tbpl1TATA box-binding protein-like protein 1; Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box. Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis. Particularly regulates genes that have a role in catabolism (By similarity). (186 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (264 aa)
gtf2h1E3 ubiquitin-protein ligase rnf168. (595 aa)
gtf2e2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (288 aa)
gtf2e1General transcription factor IIE, polypeptide 1, alpha 56kDa. (435 aa)
taf12Microtubule associated serine/threonine kinase 1. (218 aa)
gtf2h3Uncharacterized protein. (307 aa)
TAF2TATA-box binding protein associated factor 2. (1191 aa)
taf15Uncharacterized protein. (501 aa)
taf1Transcription initiation factor TFIID subunit. (1949 aa)
taf8Transcription initiation factor TFIID subunit 8; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription (By similarity). (297 aa)
taf5lRelaxin family peptide receptor 3. (588 aa)
ercc2Epoxide hydrolase 3. (760 aa)
gtf2a2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
gtf2h2General transcription factor IIH subunit. (403 aa)
TAF6LTATA-box binding protein associated factor 6 like. (574 aa)
gtf2a1lRegulator of G-protein signaling 5. (472 aa)
TAF3TATA-box binding protein associated factor 3. (929 aa)
TAF9TATA-box binding protein associated factor 9. (254 aa)
ercc3Uncharacterized protein. (806 aa)
gtf2bArginyl-tRNA synthetase 2, mitochondrial. (322 aa)
TAF4BTATA-box binding protein associated factor 4b. (892 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
taf11Cell division cycle 40. (254 aa)
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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