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hes5.4 | Uncharacterized protein. (159 aa) | ||||
dvl3 | Segment polarity protein dishevelled homolog DVL-3; Involved in the signal transduction pathway mediated by multiple Wnt genes (By similarity). Required during ciliogenesis for the docking of basal bodies to the apical plasma membrane (By similarity); Belongs to the DSH family. (713 aa) | ||||
ep300 | Suv3 like RNA helicase. (2493 aa) | ||||
dtx1 | Rhomboid domain containing 2. (623 aa) | ||||
hes4 | Transcription factor HES-4; Transcriptional repressor. Binds DNA on N-box motifs: 5'- CACNAG-3'. Promotes floor plate development and prechordal plate development. Required for lens development as early as the stage of lens field formation, partly through regulation of gene expression of the cell cycle inhibitor cdknx/p27(xic1). Required for formation of the neural crest downstream of multiple signaling pathways, and acts at the neural plate border via both DNA-binding dependent and independent mechanisms. Also acts via repressor-dependent and repressor-independent mechanisms in early [...] (281 aa) | ||||
hey2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1. (335 aa) | ||||
aqp11-2 | Aquaporin 11. (994 aa) | ||||
LOC101731574 | Bromo domain-containing protein. (84 aa) | ||||
psen1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (464 aa) | ||||
numb | PID domain-containing protein. (654 aa) | ||||
notch2 | FTO alpha-ketoglutarate dependent dioxygenase. (2455 aa) | ||||
hes1 | Transcription factor HES-1; Transcriptional repressor of a subset of early mesodermal genes including myod1 and t/bra. Binds DNA on N-box motifs: 5'-CACNAG- 3'. Acts as a negative regulator of myogenesis, mediating Notch signaling to repress expression of myod1 (By similarity). (267 aa) | ||||
dtx3 | Dtx3 protein. (353 aa) | ||||
hes5.10 | Similar to hes5 (Hairy and enhancer of split 5 (Drosophila)). (166 aa) | ||||
hes5.9 | LOC733709 protein. (155 aa) | ||||
heatr6 | BHLH domain-containing protein. (85 aa) | ||||
hes5.7 | Growth arrest specific 2. (150 aa) | ||||
hes5.5 | BHLH domain-containing protein. (263 aa) | ||||
hes5.3 | Uncharacterized protein. (160 aa) | ||||
jag1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) | ||||
dlc | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (642 aa) | ||||
hdac2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) | ||||
psen2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (451 aa) | ||||
rfng | Beta-1,3-N-acetylglucosaminyltransferase. (364 aa) | ||||
lfng | Beta-1,3-N-acetylglucosaminyltransferase. (372 aa) | ||||
NUMBL | NUMB like endocytic adaptor protein. (607 aa) | ||||
dtx2 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (592 aa) | ||||
dtx3-2 | Advillin. (212 aa) | ||||
psenen | Presenilin enhancer 2 homolog (C. elegans). (101 aa) | ||||
ovos2-3 | Alpha-2-macroglobulin like 1 pseudogene. (2368 aa) | ||||
ncor2 | EPH receptor A4. (2455 aa) | ||||
dll1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (740 aa) | ||||
dvl1 | Uncharacterized protein. (707 aa) | ||||
atxn1l | BICD family-like cargo adapter 2. (698 aa) | ||||
CIR1 | Corepressor interacting with RBPJ, 1. (559 aa) | ||||
LOC101733898 | Uncharacterized protein. (189 aa) | ||||
MAML3 | Mastermind like transcriptional coactivator 3. (1088 aa) | ||||
maml1 | Protein phosphatase methylesterase 1. (1030 aa) | ||||
adam17 | Monooxygenase, DBH-like 2, pseudogene. (834 aa) | ||||
CTBP2 | C-terminal binding protein 2. (1010 aa) | ||||
snw1 | Kelch repeat and BTB domain-containing protein 8. (549 aa) | ||||
aph1a | Regulator of G-protein signaling 9-binding protein B. (247 aa) | ||||
Notch4 | ANK_REP_REGION domain-containing protein. (168 aa) | ||||
ctbp2l | Mitogen-activated protein kinase kinase kinase 10; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (481 aa) | ||||
atxn1 | Polymerase (RNA) II subunit H. (792 aa) | ||||
ctbp1 | Leucine zipper, putative tumor suppressor family member 3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (482 aa) | ||||
KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (806 aa) | ||||
notch1 | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2535 aa) | ||||
NOTCH3 | Notch receptor 3. (2413 aa) | ||||
hdac1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (486 aa) | ||||
DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (679 aa) | ||||
hey1 | Hairy/enhancer-of-split related with YRPW motif protein 1; Downstream effector of Notch signaling. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Acts as a suppressor of neurogenesis by antagonizing proneural gene function. Functions during floorplate development. Plays a role in pronephros formation in the inhibition of distal tubule and duct cell fates and the promotion of glomus and proximal tubule formation (By similarity). (300 aa) |